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Literature DB >> 26236041

A System Calibration and Fast Iterative Reconstruction Method for Next-Generation SPECT Imagers.

Brian W Miller¹, Roel Van Holen², Harrison H Barrett¹, Lars R Furenlid¹.

Abstract

Recently, high-resolution gamma cameras have been developed with detectors containing > 105-106 elements. Single-photon emission computed tomography (SPECT) imagers based on these detectors usually also have a large number of voxel bins and therefore face memory storage issues for the system matrix when performing fast tomographic reconstructions using iterative algorithms. To address these issues, we have developed a method that parameterizes the detector response to a point source and generates the system matrix on the fly during MLEM or OSEM on graphics hardware. The calibration method, interpolation of coefficient data, and reconstruction results are presented in the context of a recently commissioned small-animal SPECT imager, called FastSPECT III.

Entities: Chemical Disease Gene Species

Keywords: Calibration; graphics processing units (GPUs); high-performance computing; image reconstruction; ordered-subset expectation maximization (OSEM); single-photon emission computed tomography (SPECT); system matrix

Year: 2012 PMID： 26236041 PMCID： PMC4520546 DOI： 10.1109/TNS.2012.2198243

Source DB: PubMed Journal: IEEE Trans Nucl Sci ISSN： 0018-9499 Impact factor: 1.679

11 in total

1. FastSPECT II: A Second-Generation High-Resolution Dynamic SPECT Imager.

Authors: Lars R Furenlid; Donald W Wilson; Yi-Chun Chen; Hyunki Kim; Philip J Pietraski; Michael J Crawford; Harrison H Barrett
Journal: IEEE Trans Nucl Sci Date: 2004-06 Impact factor: 1.679

2. A Task-Based Approach to Adaptive and Multimodality Imaging: Computation techniques are proposed for figures-of-merit to establish feasibility and optimize use of multiple imaging systems for disease diagnosis and treatment-monitoring.

Authors: Eric Clarkson; Matthew A Kupinski; Harrison H Barrett; Lars Furenlid
Journal: Proc IEEE Inst Electr Electron Eng Date: 2008-03 Impact factor: 10.961

A System Calibration and Fast Iterative Reconstruction Method for Next-Generation SPECT Imagers.

1. FastSPECT II: A Second-Generation High-Resolution Dynamic SPECT Imager.

2. A Task-Based Approach to Adaptive and Multimodality Imaging: Computation techniques are proposed for figures-of-merit to establish feasibility and optimize use of multiple imaging systems for disease diagnosis and treatment-monitoring.

3. Adaptive SPECT.

4. A prototype instrument for single pinhole small animal adaptive SPECT imaging.

5. System calibration and statistical image reconstruction for ultra-high resolution stationary pinhole SPECT.

6. Recent advances in BazookaSPECT: Real-time data processing and the development of a gamma-ray microscope.

7. A stationary hemispherical SPECT imager for three-dimensional brain imaging.

8. System Integration of FastSPECT III, a Dedicated SPECT Rodent-Brain Imager Based on BazookaSPECT Detector Technology.

9. Design and Validation of an Adaptive SPECT System: AdaptiSPECT.

10. High-resolution, anamorphic, adaptive small-animal SPECT imaging with silicon double-sided strip detectors.

1. A SPECT imager with synthetic collimation.

2. High-Resolution Anamorphic SPECT Imaging.

3. Design and performance of a small-animal imaging system using synthetic collimation.

4. Performance evaluation of small-animal multipinhole μSPECT scanners for mouse imaging.

5. Molecular Imaging in the College of Optical Sciences - An Overview of Two Decades of Instrumentation Development.