| Literature DB >> 24473369 |
Alfred Tuley1, Yane-Shih Wang, Xinqiang Fang, Yadagiri Kurra, Yohannes H Rezenom, Wenshe R Liu.
Abstract
Thirteen novel non-canonical amino acids were synthesized and tested for suppression of an amber codon using a mutant pyrrolysyl-tRNA synthetase-tRNA(Pyl)(CUA) pair. Suppression was observed with varied efficiencies. One non-canonical amino acid in particular contains an azide that can be applied for site-selective protein labeling.Entities:
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Year: 2014 PMID: 24473369 PMCID: PMC4011397 DOI: 10.1039/c3cc49068h
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222