Literature DB >> 22668563

Exposing exposure: automated anatomy-specific CT radiation exposure extraction for quality assurance and radiation monitoring.

Aaron Sodickson1, Graham I Warden, Cameron E Farkas, Ichiro Ikuta, Luciano M Prevedello, Katherine P Andriole, Ramin Khorasani.   

Abstract

PURPOSE: To develop and validate an informatics toolkit that extracts anatomy-specific computed tomography (CT) radiation exposure metrics (volume CT dose index and dose-length product) from existing digital image archives through optical character recognition of CT dose report screen captures (dose screens) combined with Digital Imaging and Communications in Medicine attributes.
MATERIALS AND METHODS: This institutional review board-approved HIPAA-compliant study was performed in a large urban health care delivery network. Data were drawn from a random sample of CT encounters that occurred between 2000 and 2010; images from these encounters were contained within the enterprise image archive, which encompassed images obtained at an adult academic tertiary referral hospital and its affiliated sites, including a cancer center, a community hospital, and outpatient imaging centers, as well as images imported from other facilities. Software was validated by using 150 randomly selected encounters for each major CT scanner manufacturer, with outcome measures of dose screen retrieval rate (proportion of correctly located dose screens) and anatomic assignment precision (proportion of extracted exposure data with correctly assigned anatomic region, such as head, chest, or abdomen and pelvis). The 95% binomial confidence intervals (CIs) were calculated for discrete proportions, and CIs were derived from the standard error of the mean for continuous variables. After validation, the informatics toolkit was used to populate an exposure repository from a cohort of 54 549 CT encounters; of which 29 948 had available dose screens.
RESULTS: Validation yielded a dose screen retrieval rate of 99% (597 of 605 CT encounters; 95% CI: 98%, 100%) and an anatomic assignment precision of 94% (summed DLP fraction correct 563 in 600 CT encounters; 95% CI: 92%, 96%). Patient safety applications of the resulting data repository include benchmarking between institutions, CT protocol quality control and optimization, and cumulative patient- and anatomy-specific radiation exposure monitoring.
CONCLUSION: Large-scale anatomy-specific radiation exposure data repositories can be created with high fidelity from existing digital image archives by using open-source informatics tools.

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Mesh:

Year:  2012        PMID: 22668563      PMCID: PMC3422099          DOI: 10.1148/radiol.12111822

Source DB:  PubMed          Journal:  Radiology        ISSN: 0033-8419            Impact factor:   11.105


  19 in total

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Journal:  Radiographics       Date:  2011-10-03       Impact factor: 5.333

2.  How effective is effective dose as a predictor of radiation risk?

Authors:  Cynthia H McCollough; Jodie A Christner; James M Kofler
Journal:  AJR Am J Roentgenol       Date:  2010-04       Impact factor: 3.959

3.  Patient-centric radiation dose monitoring in the electronic health record: what are some of the barriers and key next steps?

Authors:  Aaron Sodickson; Ramin Khorasani
Journal:  J Am Coll Radiol       Date:  2010-10       Impact factor: 5.532

Review 4.  Computed tomography--an increasing source of radiation exposure.

Authors:  David J Brenner; Eric J Hall
Journal:  N Engl J Med       Date:  2007-11-29       Impact factor: 91.245

5.  The 2007 Recommendations of the International Commission on Radiological Protection. ICRP publication 103.

Authors: 
Journal:  Ann ICRP       Date:  2007

6.  Automated extraction of radiation dose information for CT examinations.

Authors:  Tessa S Cook; Stefan Zimmerman; Andrew D A Maidment; Woojin Kim; William W Boonn
Journal:  J Am Coll Radiol       Date:  2010-11       Impact factor: 5.532

7.  CT dose index and patient dose: they are not the same thing.

Authors:  Cynthia H McCollough; Shuai Leng; Lifeng Yu; Dianna D Cody; John M Boone; Michael F McNitt-Gray
Journal:  Radiology       Date:  2011-05       Impact factor: 11.105

8.  ACR Dose Index Registry.

Authors:  Richard L Morin; Laura P Coombs; Mythreyi Bhargavan Chatfield
Journal:  J Am Coll Radiol       Date:  2011-04       Impact factor: 5.532

9.  Exposure to low-dose ionizing radiation from medical imaging procedures.

Authors:  Reza Fazel; Harlan M Krumholz; Yongfei Wang; Joseph S Ross; Jersey Chen; Henry H Ting; Nilay D Shah; Khurram Nasir; Andrew J Einstein; Brahmajee K Nallamothu
Journal:  N Engl J Med       Date:  2009-08-27       Impact factor: 91.245

10.  Recurrent CT, cumulative radiation exposure, and associated radiation-induced cancer risks from CT of adults.

Authors:  Aaron Sodickson; Pieter F Baeyens; Katherine P Andriole; Luciano M Prevedello; Richard D Nawfel; Richard Hanson; Ramin Khorasani
Journal:  Radiology       Date:  2009-04       Impact factor: 11.105

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  12 in total

1.  Multidetector CT radiation dose optimisation in adults: short- and long-term effects of a clinical audit.

Authors:  Denis Tack; Andreas Jahnen; Sarah Kohler; Nico Harpes; Viviane De Maertelaer; Carlo Back; Pierre Alain Gevenois
Journal:  Eur Radiol       Date:  2013-08-29       Impact factor: 5.315

2.  Prioritizing examination-centered over patient-centered dose reduction: a hazard of institutional "benchmarking".

Authors:  Jonathan D Eisenberg; Michael E Gilmore; Mannudeep K Kalra; Chung Yin Kong; Pari V Pandharipande
Journal:  AJR Am J Roentgenol       Date:  2014-05       Impact factor: 3.959

3.  The fisherman's cards: how to address past and future radiation exposures in clinical decision making.

Authors:  Jonathan D Eisenberg; Sarah O Lewin; Pari V Pandharipande
Journal:  AJR Am J Roentgenol       Date:  2014-02       Impact factor: 3.959

4.  Age- and gender-specific estimates of cumulative CT dose over 5 years using real radiation dose tracking data in children.

Authors:  Eunsol Lee; Hyun Woo Goo; Jae-Yeong Lee
Journal:  Pediatr Radiol       Date:  2015-03-24

5.  Journal club: How radiation exposure histories influence physician imaging decisions: a multicenter radiologist survey study.

Authors:  Pari V Pandharipande; Jonathan D Eisenberg; Laura L Avery; Martin L Gunn; Stella K Kang; Alec J Megibow; Ekin A Turan; H Benjamin Harvey; Chung Yin Kong; Emily C Dowling; Elkan F Halpern; Karen Donelan; G Scott Gazelle
Journal:  AJR Am J Roentgenol       Date:  2013-06       Impact factor: 3.959

6.  Open-Source Radiation Exposure Extraction Engine (RE3) with Patient-Specific Outlier Detection.

Authors:  Samuel J Weisenthal; Les Folio; William Kovacs; Ari Seff; Vana Derderian; Ronald M Summers; Jianhua Yao
Journal:  J Digit Imaging       Date:  2016-08       Impact factor: 4.056

7.  The feasibility of a regional CTDIvol to estimate organ dose from tube current modulated CT exams.

Authors:  Maryam Khatonabadi; Hyun J Kim; Peiyun Lu; Kyle L McMillan; Chris H Cagnon; John J DeMarco; Michael F McNitt-Gray
Journal:  Med Phys       Date:  2013-05       Impact factor: 4.071

8.  Estimating patient dose from x-ray tube output metrics: automated measurement of patient size from CT images enables large-scale size-specific dose estimates.

Authors:  Ichiro Ikuta; Graham I Warden; Katherine P Andriole; Ramin Khorasani; Aaron Sodickson
Journal:  Radiology       Date:  2013-10-28       Impact factor: 11.105

9.  CT dose survey in adults: what sample size for what precision?

Authors:  Stephen Taylor; Alain Van Muylem; Nigel Howarth; Pierre Alain Gevenois; Denis Tack
Journal:  Eur Radiol       Date:  2016-04-05       Impact factor: 5.315

Review 10.  Radiation protection perspective to recurrent medical imaging: what is known and what more is needed?

Authors:  Jenia Vassileva; Ola Holmberg
Journal:  Br J Radiol       Date:  2021-06-23       Impact factor: 3.629

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