Literature DB >> 25801905

Age- and gender-specific estimates of cumulative CT dose over 5 years using real radiation dose tracking data in children.

Eunsol Lee1, Hyun Woo Goo, Jae-Yeong Lee.   

Abstract

BACKGROUND: It is necessary to develop a mechanism to estimate and analyze cumulative radiation risks from multiple CT exams in various clinical scenarios in children.
OBJECTIVE: To identify major contributors to high cumulative CT dose estimates using actual dose-length product values collected for 5 years in children.
MATERIALS AND METHODS: Between August 2006 and July 2011 we reviewed 26,937 CT exams in 13,803 children. Among them, we included 931 children (median age 3.5 years, age range 0 days-15 years; M:F = 533:398) who had 5,339 CT exams. Each child underwent at least three CT scans and had accessible radiation dose reports. Dose-length product values were automatically extracted from DICOM files and we used recently updated conversion factors for age, gender, anatomical region and tube voltage to estimate CT radiation dose. We tracked the calculated CT dose estimates to obtain a 5-year cumulative value for each child. The study population was divided into three groups according to the cumulative CT dose estimates: high, ≥30 mSv; moderate, 10-30 mSv; and low, <10 mSv. We reviewed clinical data and CT protocols to identify major contributors to high and moderate cumulative CT dose estimates.
RESULTS: Median cumulative CT dose estimate was 5.4 mSv (range 0.5-71.1 mSv), and median number of CT scans was 4 (range 3-36). High cumulative CT dose estimates were most common in children with malignant tumors (57.9%, 11/19). High frequency of CT scans was attributed to high cumulative CT dose estimates in children with ventriculoperitoneal shunt (35 in 1 child) and malignant tumors (range 18-49). Moreover, high-dose CT protocols, such as multiphase abdomen CT (median 4.7 mSv) contributed to high cumulative CT dose estimates even in children with a low number of CT scans.
CONCLUSION: Disease group, number of CT scans, and high-dose CT protocols are major contributors to higher cumulative CT dose estimates in children.

Entities:  

Mesh:

Year:  2015        PMID: 25801905     DOI: 10.1007/s00247-015-3331-y

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN: 0301-0449


  45 in total

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