Literature DB >> 21850045

Advances in prenatal screening: the ethical dimension.

Antina de Jong1, Wybo J Dondorp, Suzanna G M Frints, Christine E M de Die-Smulders, Guido M W R de Wert.   

Abstract

Prenatal screening strategies are undergoing rapid changes owing to the introduction of new testing techniques. The overall tendency is towards broadening the scope of prenatal testing through increasingly sensitive ultrasound scans and genome-wide molecular tests. In addition, non-invasive prenatal diagnosis is likely to be introduced in the near future. These developments raise important ethical questions concerning meaningful reproductive choice, the autonomy rights of future children, equity of access and the proportionality of testing.

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Year:  2011        PMID: 21850045     DOI: 10.1038/nrg3036

Source DB:  PubMed          Journal:  Nat Rev Genet        ISSN: 1471-0056            Impact factor:   53.242


  41 in total

1.  Practice guidelines for performance of the routine mid-trimester fetal ultrasound scan.

Authors:  L J Salomon; Z Alfirevic; V Berghella; C Bilardo; E Hernandez-Andrade; S L Johnsen; K Kalache; K-Y Leung; G Malinger; H Munoz; F Prefumo; A Toi; W Lee
Journal:  Ultrasound Obstet Gynecol       Date:  2011-01       Impact factor: 7.299

Review 2.  Non-invasive prenatal diagnosis by fetal nucleic acid analysis in maternal plasma: the coming of age.

Authors:  Rossa W K Chiu; Y M Dennis Lo
Journal:  Semin Fetal Neonatal Med       Date:  2010-11-12       Impact factor: 3.926

3.  Maternal plasma DNA sequencing reveals the genome-wide genetic and mutational profile of the fetus.

Authors:  Y M Dennis Lo; K C Allen Chan; Hao Sun; Eric Z Chen; Peiyong Jiang; Fiona M F Lun; Yama W Zheng; Tak Y Leung; Tze K Lau; Charles R Cantor; Rossa W K Chiu
Journal:  Sci Transl Med       Date:  2010-12-08       Impact factor: 17.956

4.  Diagnostic utility of array-based comparative genomic hybridization (aCGH) in a prenatal setting.

Authors:  Idit Maya; Bella Davidov; Liron Gershovitz; Yael Zalzstein; Ellen Taub; Justine Coppinger; Lisa G Shaffer; Mordechai Shohat
Journal:  Prenat Diagn       Date:  2010-12       Impact factor: 3.050

Review 5.  The use of cell-free fetal nucleic acids in maternal blood for non-invasive prenatal diagnosis.

Authors:  Caroline F Wright; Hilary Burton
Journal:  Hum Reprod Update       Date:  2008-10-22       Impact factor: 15.610

Review 6.  Time to reconsider our approach to echogenic intracardiac focus and choroid plexus cysts.

Authors:  Michael Bethune
Journal:  Aust N Z J Obstet Gynaecol       Date:  2008-04       Impact factor: 2.100

7.  Non-invasive prenatal testing: ethical issues explored.

Authors:  Antina de Jong; Wybo J Dondorp; Christine E M de Die-Smulders; Suzanne G M Frints; Guido M W R de Wert
Journal:  Eur J Hum Genet       Date:  2009-12-02       Impact factor: 4.246

8.  Fetal-specific DNA methylation ratio permits noninvasive prenatal diagnosis of trisomy 21.

Authors:  Elisavet A Papageorgiou; Alex Karagrigoriou; Evdokia Tsaliki; Voula Velissariou; Nigel P Carter; Philippos C Patsalis
Journal:  Nat Med       Date:  2011-03-06       Impact factor: 53.440

9.  Serious genetic disorders: can or should they be defined?

Authors:  Dorothy C Wertz; Bartha Maria Knoppers
Journal:  Am J Med Genet       Date:  2002-02-15

10.  Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study.

Authors:  Rossa W K Chiu; Ranjit Akolekar; Yama W L Zheng; Tak Y Leung; Hao Sun; K C Allen Chan; Fiona M F Lun; Attie T J I Go; Elizabeth T Lau; William W K To; Wing C Leung; Rebecca Y K Tang; Sidney K C Au-Yeung; Helena Lam; Yu Y Kung; Xiuqing Zhang; John M G van Vugt; Ryoko Minekawa; Mary H Y Tang; Jun Wang; Cees B M Oudejans; Tze K Lau; Kypros H Nicolaides; Y M Dennis Lo
Journal:  BMJ       Date:  2011-01-11
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  37 in total

1.  A new era in prenatal testing: are we prepared?

Authors:  Dagmar Schmitz
Journal:  Med Health Care Philos       Date:  2013-08

2.  Microarrays as a diagnostic tool in prenatal screening strategies: ethical reflection.

Authors:  Antina de Jong; Wybo J Dondorp; Merryn V E Macville; Christine E M de Die-Smulders; Jan M M van Lith; Guido M W R de Wert
Journal:  Hum Genet       Date:  2014-02       Impact factor: 4.132

3.  Benefits, challenges and ethical principles associated with implementing noninvasive prenatal testing: a Delphi study.

Authors:  Charles Dupras; Stanislav Birko; Aliya Affdal; Hazar Haidar; Marie-Eve Lemoine; Vardit Ravitsky
Journal:  CMAJ Open       Date:  2018-10-31

4.  Will the introduction of non-invasive prenatal testing for Down's syndrome undermine informed choice?

Authors:  Caroline Silcock; Lih-Mei Liao; Melissa Hill; Lyn S Chitty
Journal:  Health Expect       Date:  2014-02-20       Impact factor: 3.377

5.  Old Questions, New Paradigms: Ethical, Legal, and Social Complications of Noninvasive Prenatal Testing.

Authors:  Marsha Michie; Megan Allyse
Journal:  AJOB Empir Bioeth       Date:  2015-01-01

Review 6.  The perspective from EASAC and FEAM on direct-to-consumer genetic testing for health-related purposes.

Authors:  Robin Fears; Volker ter Meulen
Journal:  Eur J Hum Genet       Date:  2012-11-21       Impact factor: 4.246

7.  To know or not to know the genomic sequence of a fetus.

Authors:  Christian Netzer; Dagmar Schmitz; Wolfram Henn
Journal:  Nat Rev Genet       Date:  2012-09-04       Impact factor: 53.242

Review 8.  Ethical, legal, social, and policy implications of behavioral genetics.

Authors:  Colleen M Berryessa; Mildred K Cho
Journal:  Annu Rev Genomics Hum Genet       Date:  2013-02-28       Impact factor: 8.929

9.  Best ethical practices for clinicians and laboratories in the provision of noninvasive prenatal testing.

Authors:  M A Allyse; L C Sayres; M Havard; J S King; H T Greely; L Hudgins; J Taylor; M E Norton; M K Cho; D Magnus; K E Ormond
Journal:  Prenat Diagn       Date:  2013-05-21       Impact factor: 3.050

10.  Should I Perform Genetic Testing? A Qualitative Look into the Decision Making Considerations of Religious Israeli Undergraduate Students.

Authors:  Merav Siani; Orit Ben-Zvi Assaraf
Journal:  J Genet Couns       Date:  2016-03-15       Impact factor: 2.537

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