Literature DB >> 21654934

Progress in electron-multiplying CCD (EMCCD) based, high-resolution, high-sensitivity x-ray detector for fluoroscopy and radiography.

Andrew T Kuhls1, Girijesh Yadava, Vikas Patel, Daniel R Bednarek, Stephen Rudin.   

Abstract

A new high-resolution, high-sensitivity, low-noise x-ray detector based on EMCCDs has been developed. The EMCCD detector module consists of a 1kx1k, 8μm pixel EMCCD camera coupled to a CsI(Tl) scintillating phosphor via a fiber optic taper (FOT). Multiple modules can be used to provide the desired field-of-view (FOV). The detector is capable of acquisitions over 30fps. The EMCCD's variable gain of up to 2000x for the pixel signal enables high sensitivity for fluoroscopic applications. With a 3:1 FOT, the detector can operate with a 144μm effective pixel size, comparable to current flat-panel detectors. Higher resolutions of 96 and 48μm pixel size can also be achieved with various binning modes. The detector MTFs and DQEs were calculated using a linear-systems analysis. The zero frequency DQE was calculated to be 59% at 74 kVp. The DQE for the 144μm pixel size was shown to exhibit quantum-noise limited behavior down to ~0.1μR using a conservative 30x gain. At this low exposure, gains above 30x showed limited improvements in DQE suggesting such increased gains may not be necessary. For operation down to 48μm pixel sizes, the detector instrumentation noise equivalent exposure (INEE), defined as the exposure where the instrumentation noise equals the quantum-noise, was <0.1μR for a 20x gain. This new technology may provide improvements over current flat-panel detectors for applications such as fluoroscopy and angiography requiring high frame rates, resolution, dynamic range and sensitivity while maintaining essentially no lag and very low INEE. Initial images from a prototype detector are also presented.

Year:  2007        PMID: 21654934      PMCID: PMC3108196          DOI: 10.1117/12.713140

Source DB:  PubMed          Journal:  Proc SPIE Int Soc Opt Eng        ISSN: 0277-786X


  13 in total

1.  Analysis of the detective quantum efficiency of a developmental detector for digital mammography.

Authors:  M B Williams; P U Simoni; L Smilowitz; M Stanton; W Phillips; A Stewart
Journal:  Med Phys       Date:  1999-11       Impact factor: 4.071

2.  Imaging performance of amorphous selenium based flat-panel detectors for digital mammography: characterization of a small area prototype detector.

Authors:  Wei Zhao; W G Ji; Anne Debrie; J A Rowlands
Journal:  Med Phys       Date:  2003-02       Impact factor: 4.071

3.  Micro-angiography for neuro-vascular imaging. II. Cascade model analysis.

Authors:  Arundhuti Ganguly; Stephen Rudin; Daniel R Bednarek; Kenneth R Hoffmann
Journal:  Med Phys       Date:  2003-11       Impact factor: 4.071

4.  Photon-counting versus an integrating CCD-based gamma camera: important consequences for spatial resolution.

Authors:  Freek J Beekman; Gerralt A de Vree
Journal:  Phys Med Biol       Date:  2005-05-25       Impact factor: 3.609

5.  New light-amplifier-based detector designs for high spatial resolution and high sensitivity CBCT mammography and fluoroscopy.

Authors:  Stephen Rudin; Andrew T Kuhls; Girijesh K Yadava; Gaurav C Josan; Ye Wu; Ravishankar N Chityala; Hussain S Rangwala; N Ciprian Ionita; Kenneth R Hoffmann; Daniel R Bednarek
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2006-12-02

6.  A survey of fluoroscopic exposure rates: AAPM Task Group No. 11 Report.

Authors:  J M Boone; D E Pfeiffer; K J Strauss; R P Rossi; P J Lin; J S Shepard; B J Conway
Journal:  Med Phys       Date:  1993 May-Jun       Impact factor: 4.071

7.  Energy and angular dependence of x-ray absorption and its effect on radiographic response in screen--film systems.

Authors:  H P Chan; K Doi
Journal:  Phys Med Biol       Date:  1983-05       Impact factor: 3.609

8.  Effects of characteristic x rays on the noise power spectra and detective quantum efficiency of photoconductive x-ray detectors.

Authors:  W Zhao; W G Ji; J A Rowlands
Journal:  Med Phys       Date:  2001-10       Impact factor: 4.071

9.  Microangiographic Image Guided Localization of a New Asymmetric Stent for Treatment of Cerebral Aneurysms.

Authors:  Ciprian N Ionita; Stephen Rudin; Kenneth R Hoffmann; Daniel R Bednarek
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2005

10.  X-ray imaging performance of structured cesium iodide scintillators.

Authors:  Wei Zhao; Goran Ristic; J A Rowlands
Journal:  Med Phys       Date:  2004-09       Impact factor: 4.071

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  15 in total

1.  A method for the determination of the two-dimensional MTF of digital radiography systems using only the noise response.

Authors:  Andrew Kuhls-Gilcrist; Daniel R Bednarek; Stephen Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2010-03-23

2.  Investigation of Noise and Contrast Sensitivity of an Electron Multiplying Charge-Coupled Device (EMCCD) based Cone Beam Micro-CT System.

Authors:  Sumukh Bysani Krishnakumar; Alexander R Podgorsak; Sv Setlur Nagesh; Amit Jain; Stephen Rudin; Daniel R Bednarek; Ciprian N Ionita
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2016-03-25

3.  LabVIEW Graphical User Interface for a New High Sensitivity, High Resolution Micro-Angio-Fluoroscopic and ROI-CBCT System.

Authors:  C Keleshis; Cn Ionita; G Yadava; V Patel; Dr Bednarek; Kr Hoffmann; A Verevkin; S Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2008

4.  Distortion, Orientation, and Translation Corrections of Tiled EMCCD Detectors for the New Solid State X-ray Image Intensifier (SSXII).

Authors:  Hidab Hamwi; Joseph W Lee; Kenneth R Hoffmann; Stephen Rudin; Aleksandr Verevkin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2008

5.  The Solid-State X-Ray Image Intensifier (SSXII): An EMCCD-Based X-Ray Detector.

Authors:  Andrew Kuhls-Gilcrist; Girijesh Yadava; Vikas Patel; Amit Jain; Daniel R Bednarek; Stephen Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2008

6.  The Solid State X-ray Image Intensifier (SSXII) in Single Photon Counting (SPC) mode.

Authors:  Andrew Kuhls-Gilcrist; Amit Jain; Daniel R Bednarek; Stephen Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2010-03-22

7.  Accurate MTF measurement in digital radiography using noise response.

Authors:  Andrew Kuhls-Gilcrist; Amit Jain; Daniel R Bednarek; Kenneth R Hoffmann; Stephen Rudin
Journal:  Med Phys       Date:  2010-02       Impact factor: 4.071

8.  Measuring the presampled MTF from a reduced number of flat-field images using the Noise Response (NR) method.

Authors:  Andrew Kuhls-Gilcrist; Amit Jain; Daniel R Bednarek; Stephen Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2011-03-01

9.  Real-time implementation of distortion corrections for a tiled EMCCD-based Solid State X-ray Image Intensifier (SSXII).

Authors:  C Keleshis; Kr Hoffmann; J Lee; H Hamwi; W Wang; Cn Ionita; Dr Bednarek; A Verevkin; S Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2009-01-01

10.  Endovascular image-guided interventions (EIGIs).

Authors:  Stephen Rudin; Daniel R Bednarek; Kenneth R Hoffmann
Journal:  Med Phys       Date:  2008-01       Impact factor: 4.071

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