PURPOSE: We compared the accuracy of magnetic resonance imaging (MRI) measurements of pulsatile flow velocity in a small tube phantom using different spatial factors versus those obtained by intraluminal Doppler guidewire examination (as reference). MATERIALS AND METHODS: We generated pulsatile flow velocities averaging about 20-290 cm/sec in a tube of 4 mm diameter; we performed phase-contrast cine MRI on pixels measuring 1.00(2)-2.50(2) mm(2). We quantified spatial peak flow velocities of a single pixel and a cluster of five pixels and spatial mean velocities within regions of interest enclosing the entire lumen in the phantom's cross-section. Finally, we compared the measurements of temporally mean and maximum flow velocity with the Doppler measurements. RESULTS: Linear correlation was excellent between both measurements of spatial peak flow velocities in one pixel. The highest spatial resolution using spatial peak flow velocities of a single pixel allowed the most accurate MRI measurements of both temporally mean and maximum pulsatile flow velocity (r = 0.97 and 0.99, respectively: MRI measurement = 0.95x + 8.9 and 0.88x + 24.0 cm/s, respectively). Otherwise, MRI measurements were significantly underestimated at lower spatial resolutions. CONCLUSION: High spatial resolution allowed accurate MRI measurement of temporally mean and maximum pulsatile flow velocity at spatial peak velocities of one pixel.
PURPOSE: We compared the accuracy of magnetic resonance imaging (MRI) measurements of pulsatile flow velocity in a small tube phantom using different spatial factors versus those obtained by intraluminal Doppler guidewire examination (as reference). MATERIALS AND METHODS: We generated pulsatile flow velocities averaging about 20-290 cm/sec in a tube of 4 mm diameter; we performed phase-contrast cine MRI on pixels measuring 1.00(2)-2.50(2) mm(2). We quantified spatial peak flow velocities of a single pixel and a cluster of five pixels and spatial mean velocities within regions of interest enclosing the entire lumen in the phantom's cross-section. Finally, we compared the measurements of temporally mean and maximum flow velocity with the Doppler measurements. RESULTS: Linear correlation was excellent between both measurements of spatial peak flow velocities in one pixel. The highest spatial resolution using spatial peak flow velocities of a single pixel allowed the most accurate MRI measurements of both temporally mean and maximum pulsatile flow velocity (r = 0.97 and 0.99, respectively: MRI measurement = 0.95x + 8.9 and 0.88x + 24.0 cm/s, respectively). Otherwise, MRI measurements were significantly underestimated at lower spatial resolutions. CONCLUSION: High spatial resolution allowed accurate MRI measurement of temporally mean and maximum pulsatile flow velocity at spatial peak velocities of one pixel.
Authors: George P Chatzimavroudis; Haosen Zhang; Sandra S Halliburton; James R Moore; Orlando P Simonetti; Paulo R Schvartzman; Arthur E Stillman; Richard D White Journal: J Magn Reson Imaging Date: 2003-01 Impact factor: 4.813
Authors: William F Fearon; Mamoo Nakamura; David P Lee; Mehrdad Rezaee; Randall H Vagelos; Sharon A Hunt; Peter J Fitzgerald; Paul G Yock; Alan C Yeung Journal: Circulation Date: 2003-09-08 Impact factor: 29.690
Authors: E O Ofili; M J Kern; A J Labovitz; J A St Vrain; J Segal; F V Aguirre; R Castello Journal: J Am Coll Cardiol Date: 1993-02 Impact factor: 24.094
Authors: R F Wilson; D E Laughlin; P H Ackell; W M Chilian; M D Holida; C J Hartley; M L Armstrong; M L Marcus; C W White Journal: Circulation Date: 1985-07 Impact factor: 29.690
Authors: Bas Versluis; Marjolein H G Dremmen; Patty J Nelemans; Joachim E Wildberger; Geert-Willem Schurink; Tim Leiner; Walter H Backes Journal: PLoS One Date: 2012-03-08 Impact factor: 3.240