Literature DB >> 20961047

Circular logic: nonribosomal peptide-like macrocyclization with a ribosomal peptide catalyst.

John A McIntosh1, Charles R Robertson, Vinayak Agarwal, Satish K Nair, Grzegorz W Bulaj, Eric W Schmidt.   

Abstract

A protease from ribosomal peptide biosynthesis macrocyclizes diverse substrates, including those resembling nonribosomal peptide and hybrid polyketide-peptide products. The proposed mechanism is analogous to thioesterase-catalyzed chemistry, but the substrates are amide bonds rather than thioesters.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20961047      PMCID： PMC2975588          DOI： 10.1021/ja1067806

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  14 in total

Review 1.  Adding new chemistries to the genetic code.

Authors:  Chang C Liu; Peter G Schultz
Journal:  Annu Rev Biochem       Date:  2010       Impact factor: 23.643

Review 2.  How structural features influence the biomembrane permeability of peptides.

Authors:  P S Burton; R A Conradi; N F Ho; A R Hilgers; R T Borchardt
Journal:  J Pharm Sci       Date:  1996-12       Impact factor: 3.534

3.  Natural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidians.

Authors:  Mohamed S Donia; Brian J Hathaway; Sebastian Sudek; Margo G Haygood; M J Rosovitz; Jacques Ravel; Eric W Schmidt
Journal:  Nat Chem Biol       Date:  2006-11-05       Impact factor: 15.040

4.  Substrate specificity and scope of MvdD, a GRASP-like ligase from the microviridin biosynthetic gene cluster.

Authors:  Benjamin Philmus; Joshua P Guerrette; Thomas K Hemscheidt
Journal:  ACS Chem Biol       Date:  2009-06-19       Impact factor: 5.100

5.  A global assembly line for cyanobactins.

Authors:  Mohamed S Donia; Jacques Ravel; Eric W Schmidt
Journal:  Nat Chem Biol       Date:  2008-04-20       Impact factor: 15.040

Review 6.  Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds.

Authors:  John A McIntosh; Mohamed S Donia; Eric W Schmidt
Journal:  Nat Prod Rep       Date:  2009-04       Impact factor: 13.423

Review 7.  Macrocyclization strategies in polyketide and nonribosomal peptide biosynthesis.

Authors:  Florian Kopp; Mohamed A Marahiel
Journal:  Nat Prod Rep       Date:  2007-05-10       Impact factor: 13.423

8.  Two enzymes catalyze the maturation of a lasso peptide in Escherichia coli.

Authors:  Sophie Duquesne; Delphine Destoumieux-Garzón; Séverine Zirah; Christophe Goulard; Jean Peduzzi; Sylvie Rebuffat
Journal:  Chem Biol       Date:  2007-07

9.  Chemoenzymatic route to macrocyclic hybrid peptide/polyketide-like molecules.

Authors:  Rahul M Kohli; Martin D Burke; Junhua Tao; Christopher T Walsh
Journal:  J Am Chem Soc       Date:  2003-06-18       Impact factor: 15.419

10.  Using marine natural products to discover a protease that catalyzes peptide macrocyclization of diverse substrates.

Authors:  Jaeheon Lee; John McIntosh; Brian J Hathaway; Eric W Schmidt
Journal:  J Am Chem Soc       Date:  2009-02-18       Impact factor: 15.419
View more
  51 in total

1.  Linking chemistry and genetics in the growing cyanobactin natural products family.

Authors:  Mohamed S Donia; Eric W Schmidt
Journal:  Chem Biol       Date:  2011-04-22

2.  Metabolic model for diversity-generating biosynthesis.

Authors:  Ma Diarey Tianero; Elizabeth Pierce; Shrinivasan Raghuraman; Debosmita Sardar; John A McIntosh; John R Heemstra; Zachary Schonrock; Brett C Covington; J Alan Maschek; James E Cox; Brian O Bachmann; Baldomero M Olivera; Duane E Ruffner; Eric W Schmidt
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-01       Impact factor: 11.205

3.  Enzymatic N- and C-Protection in Cyanobactin RiPP Natural Products.

Authors:  Debosmita Sardar; Yue Hao; Zhenjian Lin; Maho Morita; Satish K Nair; Eric W Schmidt
Journal:  J Am Chem Soc       Date:  2017-02-15       Impact factor: 15.419

Review 4.  Various mechanisms in cyclopeptide production from precursors synthesized independently of non-ribosomal peptide synthetases.

Authors:  Wenyan Xu; Liling Li; Liangcheng Du; Ninghua Tan
Journal:  Acta Biochim Biophys Sin (Shanghai)       Date:  2011-07-14       Impact factor: 3.848

5.  Molecular basis for the broad substrate selectivity of a peptide prenyltransferase.

Authors:  Yue Hao; Elizabeth Pierce; Daniel Roe; Maho Morita; John A McIntosh; Vinayak Agarwal; Thomas E Cheatham; Eric W Schmidt; Satish K Nair
Journal:  Proc Natl Acad Sci U S A       Date:  2016-11-21       Impact factor: 11.205

6.  Directing Biosynthesis: Practical Supply of Natural and Unnatural Cyanobactins.

Authors:  D Sardar; M D Tianero; E W Schmidt
Journal:  Methods Enzymol       Date:  2016-03-16       Impact factor: 1.600

7.  Three ring posttranslational circuses: insertion of oxazoles, thiazoles, and pyridines into protein-derived frameworks.

Authors:  Christopher T Walsh; Steven J Malcolmson; Travis S Young
Journal:  ACS Chem Biol       Date:  2012-01-17       Impact factor: 5.100

8.  Expanding the chemical space of synthetic cyclic peptides using a promiscuous macrocyclase from prenylagaramide biosynthesis.

Authors:  Snigdha Sarkar; Wenjia Gu; Eric W Schmidt
Journal:  ACS Catal       Date:  2020-06-17       Impact factor: 13.084

Review 9.  Biosynthetic Proteases That Catalyze the Macrocyclization of Ribosomally Synthesized Linear Peptides.

Authors:  Chayanid Ongpipattanakul; Satish K Nair
Journal:  Biochemistry       Date:  2018-03-27       Impact factor: 3.162

Review 10.  Revealing nature's synthetic potential through the study of ribosomal natural product biosynthesis.

Authors:  Kyle L Dunbar; Douglas A Mitchell
Journal:  ACS Chem Biol       Date:  2013-01-08       Impact factor: 5.100
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.