Digital mammography imaging: breast tomosynthesis and advanced applications.

This article discusses recent developments in advanced derivative technologies associated with digital mammography. Digital breast tomosynthesis, its principles, development, and early clinical trials, are reviewed. Contrast-enhanced digital mammography and combined imaging systems with digital mammography and ultrasound are also discussed. Although all these methods are currently research programs, they hold promise for improving cancer detection and characterization if early results are confirmed by clinical trials.