OBJECTIVE: The aim of this study was to test the feasibility of time-resolved computed tomography angiography (TR-CTA) for use in the lower leg. METHODS: Fifty-nine patients with suspected peripheral arterial occlusive disease were examined with a standard CTA (S-CTA) of the lower run-off and with an additional TR-CTA of the calves (12 phases; 2.5 s/phase, 80 kV, 120 mAs, volume of contrast medium 50 mL, flow rate 5.0 mL/s). For seven lower-leg artery segments, arterial contrast and the presence of venous overlay were tested for S-CTA and TR-CTA. Stenoses were classified on a three-point scale separately for S-CTA and TR-CTA, and diagnostic confidence for stenosis assessment was evaluated for both datasets. Contrast arrival times and HU values were evaluated in patients with asymmetric proximal stenoses. RESULTS: TR-CTA resulted in significantly higher contrast enhancement (P < 0.0001) and less venous overlay as compared to S-CTA (P < 0.05). Diagnostic confidence for stenosis rating was significantly higher in TR-CTA (P < 0.0001). Asymmetric proximal stenoses lead to significantly delayed and diminished contrast enhancement on the stenotic side. CONCLUSION: TR-CTA of the calves is feasible and provides higher enhancement and higher diagnostic confidence as compared to monophasic CTA of the lower legs.
OBJECTIVE: The aim of this study was to test the feasibility of time-resolved computed tomography angiography (TR-CTA) for use in the lower leg. METHODS: Fifty-nine patients with suspected peripheral arterial occlusive disease were examined with a standard CTA (S-CTA) of the lower run-off and with an additional TR-CTA of the calves (12 phases; 2.5 s/phase, 80 kV, 120 mAs, volume of contrast medium 50 mL, flow rate 5.0 mL/s). For seven lower-leg artery segments, arterial contrast and the presence of venous overlay were tested for S-CTA and TR-CTA. Stenoses were classified on a three-point scale separately for S-CTA and TR-CTA, and diagnostic confidence for stenosis assessment was evaluated for both datasets. Contrast arrival times and HU values were evaluated in patients with asymmetric proximal stenoses. RESULTS: TR-CTA resulted in significantly higher contrast enhancement (P < 0.0001) and less venous overlay as compared to S-CTA (P < 0.05). Diagnostic confidence for stenosis rating was significantly higher in TR-CTA (P < 0.0001). Asymmetric proximal stenoses lead to significantly delayed and diminished contrast enhancement on the stenotic side. CONCLUSION: TR-CTA of the calves is feasible and provides higher enhancement and higher diagnostic confidence as compared to monophasic CTA of the lower legs.
Authors: Trung D Bui; Dmitri Gelfand; Steven Whipple; Samuel E Wilson; Roy M Fujitani; Robert Conroy; Hanh Pham; Ian L Gordon Journal: Vasc Endovascular Surg Date: 2005 Nov-Dec Impact factor: 1.089
Authors: Thorsten R C Johnson; Bernhard Krauss; Martin Sedlmair; Michael Grasruck; Herbert Bruder; Dominik Morhard; Christian Fink; Sabine Weckbach; Miriam Lenhard; Bernhard Schmidt; Thomas Flohr; Maximilian F Reiser; Christoph R Becker Journal: Eur Radiol Date: 2006-12-07 Impact factor: 5.315
Authors: Oliver A Meissner; Johannes Rieger; Christof Weber; Uwe Siebert; Bernd Steckmeier; Maximilian F Reiser; Stefan O Schoenberg Journal: Radiology Date: 2005-02-16 Impact factor: 11.105
Authors: Horst R Portugaller; Helmut Schoellnast; Klaus A Hausegger; Kurt Tiesenhausen; Wilfried Amann; Andrea Berghold Journal: Eur Radiol Date: 2004-04-28 Impact factor: 5.315
Authors: Phillip M Young; Petrice M Mostardi; James F Glockner; Terri R Vrtiska; Thanila Macedo; Clifton R Haider; Stephen J Riederer Journal: J Vasc Interv Radiol Date: 2013-03 Impact factor: 3.464
Authors: S Soga; B Pomahac; N Wake; K Schultz; R F Prior; K Kumamaru; M L Steigner; D Mitsouras; J Signorelli; E M Bueno; D S Enterline; F J Rybicki Journal: AJNR Am J Neuroradiol Date: 2012-08-09 Impact factor: 3.825
Authors: Ali Adibi; Mayil S Krishnam; Sumudu Dissanayake; Adam N Plotnik; Kiyarash Mohajer; Cesar Arellano; Stefan G Ruehm Journal: Eur Radiol Date: 2014-05-08 Impact factor: 5.315
Authors: Zsolt Szucs-Farkas; Boglarka Megyeri; Andreas Christe; Peter Vock; Johannes T Heverhagen; Sebastian T Schindera Journal: Eur Radiol Date: 2014-05-28 Impact factor: 5.315
Authors: Petrice M Mostardi; Clifton R Haider; James F Glockner; Phillip M Young; Stephen J Riederer Journal: Clin Anat Date: 2011-01-12 Impact factor: 2.414
Authors: C Schabel; M N Bongers; D Ketelsen; R Syha; C Thomas; G Homann; M Notohamiprodjo; K Nikolaou; F Bamberg Journal: Radiologe Date: 2015-04 Impact factor: 0.635
Authors: Thomas Werncke; Kristina Imeen Ringe; Christian von Falck; Martin Kruschewski; Frank Wacker; Bernhard Christian Meyer Journal: PLoS One Date: 2015-04-02 Impact factor: 3.240
Authors: Barbora Horehledova; Casper Mihl; Gianluca Milanese; Rutger Brans; Nienke G Eijsvoogel; Babs M F Hendriks; Joachim E Wildberger; Marco Das Journal: Cardiovasc Intervent Radiol Date: 2018-05-22 Impact factor: 2.740