Literature DB >> 19763251

Component analysis of a new Solid State X-ray Image Intensifier (SSXII) using photon transfer and Instrumentation Noise Equivalent Exposure (INEE) measurements.

Andrew Kuhls-Gilcrist1, Daniel R Bednarek, Stephen Rudin.   

Abstract

The SSXII is a novel x-ray imager designed to improve upon the performance limitations of conventional dynamic radiographic/fluoroscopic imagers related to resolution, charge-trapping, frame-rate, and instrumentation-noise. The SSXII consists of a CsI:Tl phosphor coupled via a fiber-optic taper (FOT) to an electron-multiplying CCD (EMCCD). To facilitate investigational studies, initial designs enable interchangeability of such imaging components. Measurements of various component and configuration characteristics enable an optimization analysis with respect to overall detector performance. Photon transfer was used to characterize the EMCCD performance including ADC sensitivity, read-noise, full-well capacity and quantum efficiency. X-ray sensitivity was measured using RQA x-ray spectra. Imaging components were analyzed in terms of their MTF and transmission efficiency. The EMCCD was measured to have a very low effective read-noise of less than 1 electron rms at modest EMCCD gains, which is more than two orders-of-magnitude less than flat panel (FPD) and CMOS-based detectors. The variable signal amplification from 1 to 2000 times enables selectable sensitivities ranging from 8.5 (168) to over 15k (300k) electrons per incident x-ray photon with (without) a 4:1 FOT; these sensitivities could be readily increased with further component optimization. MTF and DQE measurements indicate the SSXII performance is comparable to current state-of-the-art detectors at low spatial frequencies and far exceeds them at higher spatial frequencies. The instrumentation noise equivalent exposure (INEE) was measured to be less than 0.3 μR out to 10 cycles/mm, which is substantially better than FPDs. Component analysis suggests that these improvements can be substantially increased with further detector optimization.

Entities:  

Year:  2009        PMID: 19763251      PMCID: PMC2745170          DOI: 10.1117/12.813957

Source DB:  PubMed          Journal:  Proc SPIE Int Soc Opt Eng        ISSN: 0277-786X


  14 in total

1.  Image quality in two phosphor-based flat panel digital radiographic detectors.

Authors:  Ehsan Samei
Journal:  Med Phys       Date:  2003-07       Impact factor: 4.071

2.  Intercomparison of methods for image quality characterization. II. Noise power spectrum.

Authors:  James T Dobbins; Ehsan Samei; Nicole T Ranger; Ying Chen
Journal:  Med Phys       Date:  2006-05       Impact factor: 4.071

3.  Performance of a high fill factor, indirect detection prototype flat-panel imager for mammography.

Authors:  Youcef El-Mohri; Larry E Antonuk; Qihua Zhao; Yi Wang; Yixin Li; Hong Du; Amit Sawant
Journal:  Med Phys       Date:  2007-01       Impact factor: 4.071

4.  Characterization of noise sources for two generations of computed radiography systems using powder and crystalline photostimulable phosphors.

Authors:  Alistair Mackenzie; Ian D Honey
Journal:  Med Phys       Date:  2007-08       Impact factor: 4.071

5.  A practical exposure-equivalent metric for instrumentation noise in x-ray imaging systems.

Authors:  G K Yadava; A T Kuhls-Gilcrist; S Rudin; V K Patel; K R Hoffmann; D R Bednarek
Journal:  Phys Med Biol       Date:  2008-08-22       Impact factor: 3.609

6.  Implementation of a high-sensitivity Micro-Angiographic Fluoroscope (HS-MAF) for in-vivo endovascular image guided interventions (EIGI) and region-of-interest computed tomography (ROI-CT).

Authors:  C N Ionita; C Keleshis; V Patel; G Yadava; K R Hoffmann; D R Bednarek; A Jain; S Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2008

7.  The Solid-State X-Ray Image Intensifier (SSXII): An EMCCD-Based X-Ray Detector.

Authors:  Andrew Kuhls-Gilcrist; Girijesh Yadava; Vikas Patel; Amit Jain; Daniel R Bednarek; Stephen Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2008

8.  New light-amplifier-based detector designs for high spatial resolution and high sensitivity CBCT mammography and fluoroscopy.

Authors:  Stephen Rudin; Andrew T Kuhls; Girijesh K Yadava; Gaurav C Josan; Ye Wu; Ravishankar N Chityala; Hussain S Rangwala; N Ciprian Ionita; Kenneth R Hoffmann; Daniel R Bednarek
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2006-12-02

9.  New microangiography system development providing improved small vessel imaging, increased contrast to noise ratios, and multi-view 3D reconstructions.

Authors:  Andrew T Kuhls; Vikas Patel; Ciprian Ionita; Peter B Noël; Alan M Walczak; Hussain S Rangwala; Kenneth R Hoffmann; Stephen Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2006

10.  Endovascular image-guided interventions (EIGIs).

Authors:  Stephen Rudin; Daniel R Bednarek; Kenneth R Hoffmann
Journal:  Med Phys       Date:  2008-01       Impact factor: 4.071

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  12 in total

1.  EMCCD-based high resolution dynamic x-ray detector for neurovascular interventions.

Authors:  P Sharma; S N Swetadri Vasan; A Jain; A Panse; A H Titus; A N Cartwright; D R Bednarek; S Rudin
Journal:  Conf Proc IEEE Eng Med Biol Soc       Date:  2011

2.  A method for the determination of the two-dimensional MTF of digital radiography systems using only the noise response.

Authors:  Andrew Kuhls-Gilcrist; Daniel R Bednarek; Stephen Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2010-03-23

3.  Dose Reduction Technique Using a Combination of a Region of Interest (ROI) Material X-Ray Attenuator and Spatially Different Temporal Filtering for Fluoroscopic Interventions.

Authors:  S N Swetadri Vasan; A Panse; A Jain; P Sharma; Ciprian N Ionita; A H Titus; A N Cartwright; D R Bednarek; S Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2012-02-23

4.  The Solid State X-ray Image Intensifier (SSXII) in Single Photon Counting (SPC) mode.

Authors:  Andrew Kuhls-Gilcrist; Amit Jain; Daniel R Bednarek; Stephen Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2010-03-22

5.  Accurate MTF measurement in digital radiography using noise response.

Authors:  Andrew Kuhls-Gilcrist; Amit Jain; Daniel R Bednarek; Kenneth R Hoffmann; Stephen Rudin
Journal:  Med Phys       Date:  2010-02       Impact factor: 4.071

6.  Measuring the presampled MTF from a reduced number of flat-field images using the Noise Response (NR) method.

Authors:  Andrew Kuhls-Gilcrist; Amit Jain; Daniel R Bednarek; Stephen Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2011-03-01

7.  Performance Trade-Off Analysis Comparing Different Front-End Configurations for a Digital X-ray Imager.

Authors:  Andrew Kuhls-Gilcrist; Amit Jain; Daniel R Bednarek; Stephen Rudin
Journal:  IEEE Nucl Sci Symp Conf Rec (1997)       Date:  2010-10-30

8.  Quantum Performance Analysis of an EMCCD-based X-ray Detector Using Photon Transfer Technique.

Authors:  Bin Qu; Andrew T Kuhls-Gilcrist; Ying Huang; Weiyuan Wang; Alexander N Cartwright; Albert H Titus; Daniel R Bednarek; Stephen Rudin
Journal:  IEEE Nucl Sci Symp Conf Rec (1997)       Date:  2010-10-30

9.  Component Level Modular Design of a Solid State X-ray Image Intensifier for an M×N Array.

Authors:  Ying Huang; Bin Qu; Prateek Sharma; Andrew Kuhls-Gilcrist; Weiyuan Wang; Albert H Titus; Alexander N Cartwright; Daniel R Bednarek; Stephen Rudin
Journal:  IEEE Nucl Sci Symp Conf Rec (1997)       Date:  2010-10-30

10.  Evaluation of intracranial aneurysm coil embolization in phantoms and patients using a high-resolution Microangiographic Fluoroscope (MAF).

Authors:  Ciprian N Ionita; Amit Jain; Brendan Loughran; Swetadri Vasan S N; Daniel R Bednarek; Elad Levy; Adnan H Siddiqui; Kenneth V Snyder; L N Hopkins; Stephen Rudin
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2012-03-02
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