PURPOSE: To determine if small hypoattenuating renal masses can be characterized as simple cysts or renal cell carcinomas on contrast-enhanced computed tomography (CT). MATERIALS AND METHODS: We retrospectively identified 20 small (<or=1.5 cm) hypoattenuating renal masses seen on contrast enhanced CT, consisting of 14 simple cysts and six renal cell carcinomas. Three independent readers recorded subjective visual impression (five-point scale from 1=definitely fluid to 5=definitely solid), CT attenuation, border (well circumscribed or ill defined), and shape (ovoid or irregular) for each lesion. RESULTS: The overall area under the receiver operator characteristic curves for subjective visual impression, CT attenuation, border, and shape were 0.97, 0.82, 0.59, and 0.55, respectively. Using dichotomized ratings (1-2=cyst and 3-5=carcinoma), subjective impression had a sensitivity and specificity of 100% and 79-100%, respectively, for the diagnosis of renal cell carcinoma. Using a threshold of 50 Hounsfield Units (HU) or more, CT attenuation had a sensitivity and specificity of 100% and 43-64%, respectively. CONCLUSION: Small hypoattenuating renal masses can be characterized with reasonable accuracy by subjective impression and CT attenuation; lesions that appear solid on visual inspection or have an attenuation value of 50 HU or more are likely to be renal cell carcinoma.
PURPOSE: To determine if small hypoattenuating renal masses can be characterized as simple cysts or renal cell carcinomas on contrast-enhanced computed tomography (CT). MATERIALS AND METHODS: We retrospectively identified 20 small (<or=1.5 cm) hypoattenuating renal masses seen on contrast enhanced CT, consisting of 14 simple cysts and six renal cell carcinomas. Three independent readers recorded subjective visual impression (five-point scale from 1=definitely fluid to 5=definitely solid), CT attenuation, border (well circumscribed or ill defined), and shape (ovoid or irregular) for each lesion. RESULTS: The overall area under the receiver operator characteristic curves for subjective visual impression, CT attenuation, border, and shape were 0.97, 0.82, 0.59, and 0.55, respectively. Using dichotomized ratings (1-2=cyst and 3-5=carcinoma), subjective impression had a sensitivity and specificity of 100% and 79-100%, respectively, for the diagnosis of renal cell carcinoma. Using a threshold of 50 Hounsfield Units (HU) or more, CT attenuation had a sensitivity and specificity of 100% and 43-64%, respectively. CONCLUSION: Small hypoattenuating renal masses can be characterized with reasonable accuracy by subjective impression and CT attenuation; lesions that appear solid on visual inspection or have an attenuation value of 50 HU or more are likely to be renal cell carcinoma.
Authors: Cedela Abdulla; Mannudeep K Kalra; Sanjay Saini; Michael M Maher; Aamir Ahmad; Elkan Halpern; Stuart G Silverman Journal: AJR Am J Roentgenol Date: 2002-12 Impact factor: 3.959
Authors: Joan P Heneghan; Audrey L Spielmann; Douglas H Sheafor; Mark A Kliewer; David M DeLong; Rendon C Nelson Journal: J Comput Assist Tomogr Date: 2002 Jan-Feb Impact factor: 1.826
Authors: Andrew D Rule; Kewalee Sasiwimonphan; John C Lieske; Mira T Keddis; Vicente E Torres; Terri J Vrtiska Journal: Am J Kidney Dis Date: 2012-03-06 Impact factor: 8.860
Authors: Felix Y Yap; Bino A Varghese; Steven Y Cen; Darryl H Hwang; Xiaomeng Lei; Bhushan Desai; Christopher Lau; Lindsay L Yang; Austin J Fullenkamp; Simin Hajian; Marielena Rivas; Megha Nayyar Gupta; Brian D Quinn; Manju Aron; Mihir M Desai; Monish Aron; Assad A Oberai; Inderbir S Gill; Vinay A Duddalwar Journal: Eur Radiol Date: 2020-08-15 Impact factor: 5.315