Literature DB >> 18675483

Engineering microbial consortia: a new frontier in synthetic biology.

Katie Brenner1, Lingchong You, Frances H Arnold.   

Abstract

Microbial consortia are ubiquitous in nature and are implicated in processes of great importance to humans, from environmental remediation and wastewater treatment to assistance in food digestion. Synthetic biologists are honing their ability to program the behavior of individual microbial populations, forcing the microbes to focus on specific applications, such as the production of drugs and fuels. Given that microbial consortia can perform even more complicated tasks and endure more changeable environments than monocultures can, they represent an important new frontier for synthetic biology. Here, we review recent efforts to engineer synthetic microbial consortia, and we suggest future applications.

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Year:  2008        PMID: 18675483     DOI: 10.1016/j.tibtech.2008.05.004

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  204 in total

1.  Application of phosphate solubilizing bacteria in immobilization of Pb and Cd in soil.

Authors:  Zhimin Yuan; Honghong Yi; Tianqi Wang; Yiyue Zhang; Xiaozhe Zhu; Jun Yao
Journal:  Environ Sci Pollut Res Int       Date:  2017-08-04       Impact factor: 4.223

Review 2.  Dynamics in the mixed microbial concourse.

Authors:  Edwin H Wintermute; Pamela A Silver
Journal:  Genes Dev       Date:  2010-12-01       Impact factor: 11.361

3.  Distributed biological computation with multicellular engineered networks.

Authors:  Sergi Regot; Javier Macia; Núria Conde; Kentaro Furukawa; Jimmy Kjellén; Tom Peeters; Stefan Hohmann; Eulàlia de Nadal; Francesc Posas; Ricard Solé
Journal:  Nature       Date:  2010-12-08       Impact factor: 49.962

Review 4.  Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms.

Authors:  Marnix H Medema; Rainer Breitling; Roel Bovenberg; Eriko Takano
Journal:  Nat Rev Microbiol       Date:  2010-12-29       Impact factor: 60.633

5.  Design of a bistable switch to control cellular uptake.

Authors:  Diego A Oyarzún; Madalena Chaves
Journal:  J R Soc Interface       Date:  2015-12-06       Impact factor: 4.118

6.  SYNTHETIC BIOLOGY. Emergent genetic oscillations in a synthetic microbial consortium.

Authors:  Ye Chen; Jae Kyoung Kim; Andrew J Hirning; Krešimir Josić; Matthew R Bennett
Journal:  Science       Date:  2015-08-28       Impact factor: 47.728

Review 7.  Foundations for the design and implementation of synthetic genetic circuits.

Authors:  Adrian L Slusarczyk; Allen Lin; Ron Weiss
Journal:  Nat Rev Genet       Date:  2012-05-18       Impact factor: 53.242

Review 8.  Engineering microbial systems to explore ecological and evolutionary dynamics.

Authors:  Yu Tanouchi; Robert P Smith; Lingchong You
Journal:  Curr Opin Biotechnol       Date:  2012-02-04       Impact factor: 9.740

Review 9.  Harnessing nature's toolbox: regulatory elements for synthetic biology.

Authors:  Patrick M Boyle; Pamela A Silver
Journal:  J R Soc Interface       Date:  2009-03-04       Impact factor: 4.118

Review 10.  Understanding and Engineering Distributed Biochemical Pathways in Microbial Communities.

Authors:  Xinyun Cao; Joshua J Hamilton; Ophelia S Venturelli
Journal:  Biochemistry       Date:  2018-11-20       Impact factor: 3.162

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