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Literature DB >> 19324675

Harnessing nature's toolbox: regulatory elements for synthetic biology.

Abstract

Synthetic biologists seek to engineer complex biological systems composed of modular elements. Achieving higher complexity in engineered biological organisms will require manipulating numerous systems of biological regulation: transcription; RNA interactions; protein signalling; and metabolic fluxes, among others. Exploiting the natural modularity at each level of biological regulation will promote the development of standardized tools for designing biological systems.

Mesh：

Substances：
Proteins
RNA

Year: 2009 PMID： 19324675 PMCID： PMC2843961 DOI： 10.1098/rsif.2008.0521.focus

Source DB: PubMed Journal: J R Soc Interface ISSN： 1742-5662 Impact factor: 4.118

100 in total

1. Regulation of gene expression in flux balance models of metabolism.

Authors: M W Covert; C H Schilling; B Palsson
Journal: J Theor Biol Date: 2001-11-07 Impact factor: 2.691

Review 2. Histidine kinases and response regulator proteins in two-component signaling systems.

Authors: A H West; A M Stock
Journal: Trends Biochem Sci Date: 2001-06 Impact factor: 13.807

3. Evolution of key cell signaling and adhesion protein families predates animal origins.

Authors: Nicole King; Christopher T Hittinger; Sean B Carroll
Journal: Science Date: 2003-07-18 Impact factor: 47.728

Review 4. Gene regulation by riboswitches.

Authors: Maumita Mandal; Ronald R Breaker
Journal: Nat Rev Mol Cell Biol Date: 2004-06 Impact factor: 94.444

5. Engineering modular protein interaction switches by sequence overlap.

Authors: Nathan A Sallee; Brian J Yeh; Wendell A Lim
Journal: J Am Chem Soc Date: 2007-03-24 Impact factor: 15.419

6. Synthetic ecosystems based on airborne inter- and intrakingdom communication.

Authors: Wilfried Weber; Marie Daoud-El Baba; Martin Fussenegger
Journal: Proc Natl Acad Sci U S A Date: 2007-06-05 Impact factor: 11.205

7. Modular decomposition of metabolic systems via null-space analysis.

Authors: Mark G Poolman; Cristiana Sebu; Michael K Pidcock; David A Fell
Journal: J Theor Biol Date: 2007-08-19 Impact factor: 2.691

8. A co-fermentation strategy to consume sugar mixtures effectively.

Authors: Mark A Eiteman; Sarah A Lee; Elliot Altman
Journal: J Biol Eng Date: 2008-02-27 Impact factor: 4.355

9. A synthetic Escherichia coli predator-prey ecosystem.

Authors: Frederick K Balagaddé; Hao Song; Jun Ozaki; Cynthia H Collins; Matthew Barnet; Frances H Arnold; Stephen R Quake; Lingchong You
Journal: Mol Syst Biol Date: 2008-04-15 Impact factor: 11.429

10. A fast, robust and tunable synthetic gene oscillator.

Authors: Jesse Stricker; Scott Cookson; Matthew R Bennett; William H Mather; Lev S Tsimring; Jeff Hasty
Journal: Nature Date: 2008-10-29 Impact factor: 49.962

16 in total

1. A Synthetic Gene Circuit for Self-Regulating Delivery of Biologic Drugs in Engineered Tissues.

Authors: Lara Pferdehirt; Alison K Ross; Jonathan M Brunger; Farshid Guilak
Journal: Tissue Eng Part A Date: 2019-05 Impact factor: 3.845

Review 2. Opportunities for microfluidic technologies in synthetic biology.

Authors: Shelly Gulati; Vincent Rouilly; Xize Niu; James Chappell; Richard I Kitney; Joshua B Edel; Paul S Freemont; Andrew J deMello
Journal: J R Soc Interface Date: 2009-05-27 Impact factor: 4.118

3. Synthetic biology: history, challenges and prospects.

Authors: Jim Haseloff; Jim Ajioka
Journal: J R Soc Interface Date: 2009-06-03 Impact factor: 4.118

4. Intramolecular arrangement of sensor and regulator overcomes relaxed specificity in hybrid two-component systems.

Authors: Guy E Townsend; Varsha Raghavan; Igor Zwir; Eduardo A Groisman
Journal: Proc Natl Acad Sci U S A Date: 2012-12-19 Impact factor: 11.205

Review 5. Parts plus pipes: synthetic biology approaches to metabolic engineering.

Authors: Patrick M Boyle; Pamela A Silver
Journal: Metab Eng Date: 2011-10-25 Impact factor: 9.783

6. Modularity of a carbon-fixing protein organelle.

Authors: Walter Bonacci; Poh K Teng; Bruno Afonso; Henrike Niederholtmeyer; Patricia Grob; Pamela A Silver; David F Savage
Journal: Proc Natl Acad Sci U S A Date: 2011-12-19 Impact factor: 11.205

7. A synthetic circuit for selectively arresting daughter cells to create aging populations.

Authors: Bruno Afonso; Pamela A Silver; Caroline M Ajo-Franklin
Journal: Nucleic Acids Res Date: 2010-02-11 Impact factor: 16.971

8. Avoiding transcription factor competition at promoter level increases the chances of obtaining oscillation.

Authors: Andreea Munteanu; Marco Constante; Mark Isalan; Ricard V Solé
Journal: BMC Syst Biol Date: 2010-05-17

9. Flipping DNA to generate and regulate microbial consortia.

Authors: Rohini Ramadas; Mukund Thattai
Journal: Genetics Date: 2009-10-26 Impact factor: 4.562

Review 10. Rewiring cells: synthetic biology as a tool to interrogate the organizational principles of living systems.

Authors: Caleb J Bashor; Andrew A Horwitz; Sergio G Peisajovich; Wendell A Lim
Journal: Annu Rev Biophys Date: 2010 Impact factor: 12.981