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Literature DB >> 17172548

MED-EL Cochlear implants: state of the art and a glimpse into the future.

Ingeborg Hochmair¹, Peter Nopp, Claude Jolly, Marcus Schmidt, Hansjörg Schösser, Carolyn Garnham, Ilona Anderson.

Abstract

Cochlear implantation is an accepted treatment method for adults and children with severe to profound hearing loss. Confidence in technology has led to changes in individuals who can receive a cochlear implant and changes in expected benefit with a cochlear implant. This article describes the research and development activities at MED-EL, which make possible the implementation of new speech-coding strategies as well as the application of acoustic and electric stimulation via a combined speech processor in MED-EL devices. Research on benefits from bilateral cochlear implantation and electric-acoustic stimulation are also reviewed. Finally, the potential of drug delivery systems is considered as a way to improve cochlear implant outcomes, and results from preliminary evaluations of a hybrid cochlear implant system with drug delivery capabilities are reported.

Entities: Disease Species

Mesh：

Year: 2006 PMID： 17172548 PMCID： PMC4111377 DOI： 10.1177/1084713806296720

Source DB: PubMed Journal: Trends Amplif ISSN： 1084-7138

47 in total

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Journal: Nature Date: 2002-03-07 Impact factor: 49.962

2. [Benefit of bilateral cochlear implantation on congenital prelingually deafened Chinese-speaking children].

Authors: Weijia Kong; Lisheng Yu; You Xu; Jianxin Yue; Xingao Xiong; Lixin Zhu; Jiade Duan
Journal: Lin Chuang Er Bi Yan Hou Ke Za Zhi Date: 2003-10

3. Substance distribution in a cochlea model using different pump rates for cochlear implant drug delivery electrode prototypes.

Authors: Gerrit Paasche; Lars Bögel; Martin Leinung; Thomas Lenarz; Timo Stöver
Journal: Hear Res Date: 2005-12-07 Impact factor: 3.208

4. Single-channel versus bilateral multichannel cochlear implant results: a case report.

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Journal: Ear Hear Date: 1991-12 Impact factor: 3.570

5. Drug delivery to the cochlea after implantation: consideration of the risk factors.

Authors: C Garnham; G Reetz; C Jolly; J Miller; A Salt; F Beal
Journal: Cochlear Implants Int Date: 2005-09

6. A novel microperfusion system for the long-term local supply of drugs to the inner ear: implantation and function in the rat model.

Authors: M Praetorius; A Limberger; M Müller; R Lehner; B Schick; H P Zenner; P Plinkert; M Knipper
Journal: Audiol Neurootol Date: 2001 Sep-Oct Impact factor: 1.854

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Journal: J Acoust Soc Am Date: 1989-10 Impact factor: 1.840

8. Superiority of bilateral cochlear implantation over unilateral cochlear implantation in tone discrimination in chinese patients.

Authors: Dennis Kin-Kwok Au; Yau Hui; William Ignace Wei
Journal: Am J Otolaryngol Date: 2003 Jan-Feb Impact factor: 1.808

9. Psychophysical and speech perception studies: a case report on a binaural cochlear implant subject.

Authors: R J van Hoesel; Y C Tong; R D Hollow; G M Clark
Journal: J Acoust Soc Am Date: 1993-12 Impact factor: 1.840

10. Binaural cochlear implants.

Authors: J D Green; D M Mills; B A Bell; W M Luxford; L L Tonokawa
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41 in total

1. Effect of multi-electrode configuration on sensitivity to interaural timing differences in bilateral cochlear-implant users.

Authors: Alan Kan; Heath G Jones; Ruth Y Litovsky
Journal: J Acoust Soc Am Date: 2015-12 Impact factor: 1.840

2. AAV-Mediated Neurotrophin Gene Therapy Promotes Improved Survival of Cochlear Spiral Ganglion Neurons in Neonatally Deafened Cats: Comparison of AAV2-hBDNF and AAV5-hGDNF.

Authors: Patricia A Leake; Stephen J Rebscher; Chantale Dore'; Omar Akil
Journal: J Assoc Res Otolaryngol Date: 2019-06-20

Review 3. Principles of local drug delivery to the inner ear.

Authors: Alec N Salt; Stefan K Plontke
Journal: Audiol Neurootol Date: 2009-11-16 Impact factor: 1.854

Review 4. Importance of cochlear health for implant function.

Authors: Bryan E Pfingst; Ning Zhou; Deborah J Colesa; Melissa M Watts; Stefan B Strahl; Soha N Garadat; Kara C Schvartz-Leyzac; Cameron L Budenz; Yehoash Raphael; Teresa A Zwolan
Journal: Hear Res Date: 2014-09-28 Impact factor: 3.208

5. Perception of pure tones and iterated rippled noise for normal hearing and cochlear implant users.

Authors: Richard T Penninger; Wade W Chien; Patpong Jiradejvong; Emily Boeke; Courtney L Carver; Charles J Limb
Journal: Trends Amplif Date: 2013-03

6. Improving speech perception in noise with current focusing in cochlear implant users.

Authors: Arthi G Srinivasan; Monica Padilla; Robert V Shannon; David M Landsberger
Journal: Hear Res Date: 2013-03-01 Impact factor: 3.208

Review 7. Intracochlear drug delivery systems.

Authors: Jeffrey T Borenstein
Journal: Expert Opin Drug Deliv Date: 2011-05-26 Impact factor: 6.648