Literature DB >> 16612057

How do women decide? Accepting or declining BRCA1/2 testing in a nationwide clinical sample in the United States.

Pamela Sankar1, Paul Root Wolpe, Nora L Jones, Mildred Cho.   

Abstract

OBJECTIVE: To examine the role of the practitioner, informed consent, and genetic counseling in genetic testing decisions and to assess their relative influence on women's decision to have clinical BRCA1/2 testing.
METHODS: Qualitative study using in-depth open-ended interviews with 68 women who had considered clinical BRCA1/2 testing.
RESULTS: Slightly less than half of the women who had considered BRCA1/2 testing were found to have had a clear and preexisting desire to test or not to test, irrespective of practitioner attitude or advice.
CONCLUSION: The decision to accept or decline genetic testing is the result of a complex process that goes beyond interactions between health care providers and patients, indicating a caution against exclusive reliance on informed consent or counseling encounters.

Entities:  

Mesh:

Year:  2006        PMID: 16612057      PMCID: PMC1317096          DOI: 10.1159/000091484

Source DB:  PubMed          Journal:  Community Genet        ISSN: 1422-2795


  20 in total

1.  Evaluation of nurses and genetic counselors as providers of education about breast cancer susceptibility testing.

Authors:  B A Bernhardt; G Geller; T Doksum; S A Metz
Journal:  Oncol Nurs Forum       Date:  2000 Jan-Feb       Impact factor: 2.172

2.  Psychosocial factors predicting BRCA1/BRCA2 testing decisions in members of hereditary breast and ovarian cancer families.

Authors:  B B Biesecker; N Ishibe; D W Hadley; T R Giambarresi; R G Kase; C Lerman; J P Struewing
Journal:  Am J Med Genet       Date:  2000-08-14

3.  Factors associated with decisions about clinical BRCA1/2 testing.

Authors:  K Armstrong; K Calzone; J Stopfer; G Fitzgerald; J Coyne; B Weber
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2000-11       Impact factor: 4.254

4.  Genetic testing for a BRCA1 mutation: prophylactic surgery and screening behavior in women 2 years post testing.

Authors:  Jeffrey R Botkin; Ken R Smith; Robert T Croyle; Bonnie J Baty; Jean E Wylie; Debra Dutson; Anna Chan; Heidi A Hamann; Caryn Lerman; Jamie McDonald; Vickie Venne; John H Ward; Elaine Lyon
Journal:  Am J Med Genet A       Date:  2003-04-30       Impact factor: 2.802

5.  Statement of the American Society of Clinical Oncology: genetic testing for cancer susceptibility, Adopted on February 20, 1996.

Authors: 
Journal:  J Clin Oncol       Date:  1996-05       Impact factor: 44.544

6.  Predictors of cognitive appraisals following genetic testing for BRCA1 and BRCA2 mutations.

Authors:  Chanita Hughes Halbert; Marc D Schwartz; Lari Wenzel; Steven Narod; Beth N Peshkin; David Cella; Caryn Lerman
Journal:  J Behav Med       Date:  2004-08

7.  Early adoption of BRCA1/2 testing: who and why.

Authors:  Katrina Armstrong; Janet Weiner; Barbara Weber; David A Asch
Journal:  Genet Med       Date:  2003 Mar-Apr       Impact factor: 8.822

8.  BRCA1 testing in families with hereditary breast-ovarian cancer. A prospective study of patient decision making and outcomes.

Authors:  C Lerman; S Narod; K Schulman; C Hughes; A Gomez-Caminero; G Bonney; K Gold; B Trock; D Main; J Lynch; C Fulmore; C Snyder; S J Lemon; T Conway; P Tonin; G Lenoir; H Lynch
Journal:  JAMA       Date:  1996-06-26       Impact factor: 56.272

9.  American Society of Clinical Oncology policy statement update: genetic testing for cancer susceptibility.

Authors: 
Journal:  J Clin Oncol       Date:  2003-04-11       Impact factor: 44.544

10.  Interest in BRCA1/2 testing in a primary care population.

Authors:  Katrina Armstrong; Barbara Weber; Peter A Ubel; Carmen Guerra; J Sanford Schwartz
Journal:  Prev Med       Date:  2002-06       Impact factor: 4.018

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  18 in total

1.  Young Women's Perceptions Regarding Communication with Healthcare Providers About Breast Cancer, Risk, and Prevention.

Authors:  Natasha Buchanan Lunsford; Karena F Sapsis; Betsy Smither; Jennifer Reynolds; Ben Wilburn; Temeika Fairley
Journal:  J Womens Health (Larchmt)       Date:  2017-05-04       Impact factor: 2.681

2.  Motivators for participation in a whole-genome sequencing study: implications for translational genomics research.

Authors:  Flavia M Facio; Stephanie Brooks; Johanna Loewenstein; Susannah Green; Leslie G Biesecker; Barbara B Biesecker
Journal:  Eur J Hum Genet       Date:  2011-07-06       Impact factor: 4.246

3.  Exploring the views of parents regarding dietary habits of their young cancer-surviving children.

Authors:  Jennifer Cohen; Claire E Wakefield; Linda C Tapsell; Karen Walton; Catharine A K Fleming; Richard J Cohn
Journal:  Support Care Cancer       Date:  2014-08-17       Impact factor: 3.603

4.  Recognizing BRCA gene mutation risk subsequent to breast cancer diagnosis in southwestern Ontario.

Authors:  Meredith Vanstone; Winsion Chow; Laura Lester; Peter Ainsworth; Jeff Nisker; Muriel Brackstone
Journal:  Can Fam Physician       Date:  2012-05       Impact factor: 3.275

5.  Attitudes of patients with cancer about personalized medicine and somatic genetic testing.

Authors:  Stacy W Gray; Katherine Hicks-Courant; Christopher S Lathan; Levi Garraway; Elyse R Park; Jane C Weeks
Journal:  J Oncol Pract       Date:  2012-08-07       Impact factor: 3.840

6.  Risk information exposure and direct-to-consumer genetic testing for BRCA mutations among women with a personal or family history of breast or ovarian cancer.

Authors:  Stacy W Gray; Cristin O'Grady; Lauren Karp; Daniel Smith; J Sanford Schwartz; Robert C Hornik; Katrina Armstrong
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2009-03-24       Impact factor: 4.254

7.  What Black Women Know and Want to Know About Counseling and Testing for BRCA1/2.

Authors:  Inez Adams; Juleen Christopher; Karen Patricia Williams; Vanessa B Sheppard
Journal:  J Cancer Educ       Date:  2015-06       Impact factor: 2.037

8.  Underutilization of BRCA1/2 testing to guide breast cancer treatment: black and Hispanic women particularly at risk.

Authors:  Douglas E Levy; Stacey D Byfield; Catherine B Comstock; Judy E Garber; Sapna Syngal; William H Crown; Alexandra E Shields
Journal:  Genet Med       Date:  2011-04       Impact factor: 8.822

9.  What is in a cause? Exploring the relationship between genetic cause and felt stigma.

Authors:  Pamela Sankar; Mildred K Cho; Paul Root Wolpe; Cynthia Schairer
Journal:  Genet Med       Date:  2006-01       Impact factor: 8.822

10.  Knowledge, Attitudes, Willingness to Pay, and Patient Preferences About Genetic Testing and Subsequent Risk Management for Cancer Prevention.

Authors:  Fangjian Guo; Jacqueline M Hirth; Erika L Fuchs; Leslie E Cofie; Veronica Brown; Yong-Fang Kuo; Maria E Fernandez; Abbey B Berenson
Journal:  J Cancer Educ       Date:  2022-04       Impact factor: 2.037

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