Literature DB >> 16557096

The 50cc Penn State left ventricular assist device: a parametric study of valve orientation flow dynamics.

James W Kreider1, Keefe B Manning, Leslie A Oley, Arnold A Fontaine, Steven Deutsch.   

Abstract

We investigated the flow fields associated with the Bjork-Shiley Monostrut mechanical heart valve in the mitral position of the 50 cc Penn State left ventricular assist device. The valve orientation was adjusted whereby flow field data was collected using planar particle image velocimetry. The mitral valve was rotated from 0 to 45 degrees, in 15-degree increments. For each valve orientation, measurements were made in three planes (3, 5, and 8 mm from the front wall) parallel to the device pusher plate. Penetration of the inlet jet was affected by the valve orientation with more intense and longer duration wall washing motion occurring at 45 degrees. As a result, the 45-degree mitral valve orientation is recommended to help prevent areas of thrombus deposition. Valve orientation is an important aspect of assist device design.

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Year:  2006        PMID: 16557096     DOI: 10.1097/01.mat.0000199750.89636.77

Source DB:  PubMed          Journal:  ASAIO J        ISSN: 1058-2916            Impact factor:   2.872


  10 in total

1.  A fluid dynamics study in a 50 cc pulsatile ventricular assist device: influence of heart rate variability.

Authors:  Jason C Nanna; Michael A Navitsky; Stephen R Topper; Steven Deutsch; Keefe B Manning
Journal:  J Biomech Eng       Date:  2011-10       Impact factor: 2.097

2.  Flow visualization for different port angles of a pulsatile ventricular assist device.

Authors:  Eiki Akagawa; Hwansung Lee; Eisuke Tatsumi; Akihiko Homma; Tomonori Tsukiya; Yoshiyuki Taenaka
Journal:  J Artif Organs       Date:  2011-10-30       Impact factor: 1.731

3.  Effects of mechanical valve orifice direction on the flow pattern in a ventricular assist device.

Authors:  Eiki Akagawa; Hwansung Lee; Eisuke Tatsumi; Akihiko Homma; Tomonori Tsukiya; Nobumasa Katagiri; Yukihide Kakuta; Tomohiro Nishinaka; Toshihide Mizuno; Kei Ota; Rei Kansaku; Yoshiyuki Taenaka
Journal:  J Artif Organs       Date:  2007-06-20       Impact factor: 1.731

Review 4.  Biomechanics.

Authors:  Masahiro Nishida
Journal:  J Artif Organs       Date:  2009-03-29       Impact factor: 1.731

5.  Validation of a CFD methodology for positive displacement LVAD analysis using PIV data.

Authors:  Richard B Medvitz; Varun Reddy; Steve Deutsch; Keefe B Manning; Eric G Paterson
Journal:  J Biomech Eng       Date:  2009-11       Impact factor: 2.097

6.  Flow field study comparing design iterations of a 50 cc left ventricular assist device.

Authors:  Jason C Nanna; Jennifer A Wivholm; Steven Deutsch; Keefe B Manning
Journal:  ASAIO J       Date:  2011 Sep-Oct       Impact factor: 2.872

7.  The Use of Fluid Mechanics to Predict Regions of Microscopic Thrombus Formation in Pulsatile VADs.

Authors:  Stephen R Topper; Michael A Navitsky; Richard B Medvitz; Eric G Paterson; Christopher A Siedlecki; Margaret J Slattery; Steven Deutsch; Gerson Rosenberg; Keefe B Manning
Journal:  Cardiovasc Eng Technol       Date:  2014-03-01       Impact factor: 2.495

8.  A thrombus susceptibility comparison of two pulsatile Penn State 50 cc left ventricular assist device designs.

Authors:  Michael A Navitsky; Steven Deutsch; Keefe B Manning
Journal:  Ann Biomed Eng       Date:  2012-07-24       Impact factor: 3.934

9.  Flow visualization of three-dimensionality inside the 12 cc Penn State pulsatile pediatric ventricular assist device.

Authors:  Breigh N Roszelle; Steven Deutsch; Keefe B Manning
Journal:  Ann Biomed Eng       Date:  2010-02       Impact factor: 3.934

10.  Platelet adhesion to polyurethane urea under pulsatile flow conditions.

Authors:  Michael A Navitsky; Joshua O Taylor; Alexander B Smith; Margaret J Slattery; Steven Deutsch; Christopher A Siedlecki; Keefe B Manning
Journal:  Artif Organs       Date:  2014-04-09       Impact factor: 3.094

  10 in total

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