Literature DB >> 20353260

Validation of a CFD methodology for positive displacement LVAD analysis using PIV data.

Richard B Medvitz1, Varun Reddy, Steve Deutsch, Keefe B Manning, Eric G Paterson.   

Abstract

Computational fluid dynamics (CFD) is used to asses the hydrodynamic performance of a positive displacement left ventricular assist device. The computational model uses implicit large eddy simulation direct resolution of the chamber compression and modeled valve closure to reproduce the in vitro results. The computations are validated through comparisons with experimental particle image velocimetry (PIV) data. Qualitative comparisons of flow patterns, velocity fields, and wall-shear rates demonstrate a high level of agreement between the computations and experiments. Quantitatively, the PIV and CFD show similar probed velocity histories, closely matching jet velocities and comparable wall-strain rates. Overall, it has been shown that CFD can provide detailed flow field and wall-strain rate data, which is important in evaluating blood pump performance.

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Year:  2009        PMID: 20353260      PMCID: PMC3607448          DOI: 10.1115/1.4000116

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  19 in total

1.  Fluid dynamics of a pediatric ventricular assist device.

Authors:  C Bachmann; G Hugo; G Rosenberg; S Deutsch; A Fontaine; J M Tarbell
Journal:  Artif Organs       Date:  2000-05       Impact factor: 3.094

2.  A reevaluation and discussion on the threshold limit for hemolysis in a turbulent shear flow.

Authors:  P C Lu; H C Lai; J S Liu
Journal:  J Biomech       Date:  2001-10       Impact factor: 2.712

3.  Flow mixing and fluid residence times in a model of a ventricular assist device.

Authors:  C S König; C Clark
Journal:  Med Eng Phys       Date:  2001-03       Impact factor: 2.242

4.  Diaphragm motion affects flow patterns in an artificial heart.

Authors:  Pramote Hochareon; Keefe B Manning; Arnold A Fontaine; Steven Deutsch; John M Tarbell
Journal:  Artif Organs       Date:  2003-12       Impact factor: 3.094

5.  Development and validation of a computational fluid dynamics methodology for simulation of pulsatile left ventricular assist devices.

Authors:  Richard B Medvitz; James W Kreider; Keefe B Manning; Arnold A Fontaine; Steven Deutsch; Eric G Paterson
Journal:  ASAIO J       Date:  2007 Mar-Apr       Impact factor: 2.872

6.  Local blood residence times in the Penn State artificial heart.

Authors:  D E Francischelli; J M Tarbell; D B Geselowitz
Journal:  Artif Organs       Date:  1991-06       Impact factor: 3.094

7.  Morphological, biochemical, and functional changes in human platelets subjected to shear stress.

Authors:  C H Brown; L B Leverett; C W Lewis; C P Alfrey; J D Hellums
Journal:  J Lab Clin Med       Date:  1975-09

8.  Bridge to heart transplantation: the Penn State experience.

Authors:  J A Magovern; J L Pennock; D B Campbell; W E Pae; W S Pierce; J A Waldhausen
Journal:  J Heart Transplant       Date:  1986 May-Jun

9.  In vivo testing of a completely implanted total artificial heart system.

Authors:  A J Snyder; G Rosenberg; W J Weiss; S K Ford; R A Nazarian; D L Hicks; J A Marlotte; O Kawaguchi; G A Prophet; J S Sapirstein
Journal:  ASAIO J       Date:  1993 Jul-Sep       Impact factor: 2.872

10.  Visualization and analysis of mural thrombogenesis on collagen, polyurethane and nylon.

Authors:  J A Hubbell; L V McIntire
Journal:  Biomaterials       Date:  1986-09       Impact factor: 12.479

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  10 in total

1.  Toward the Virtual Benchmarking of Pneumatic Ventricular Assist Devices: Application of a Novel Fluid-Structure Interaction-Based Strategy to the Penn State 12 cc Device.

Authors:  Alessandro Caimi; Francesco Sturla; Bryan Good; Marco Vidotto; Rachele De Ponti; Filippo Piatti; Keefe B Manning; Alberto Redaelli
Journal:  J Biomech Eng       Date:  2017-08-01       Impact factor: 2.097

2.  The Use of Fluid Mechanics to Predict Regions of Microscopic Thrombus Formation in Pulsatile VADs.

Authors:  Stephen R Topper; Michael A Navitsky; Richard B Medvitz; Eric G Paterson; Christopher A Siedlecki; Margaret J Slattery; Steven Deutsch; Gerson Rosenberg; Keefe B Manning
Journal:  Cardiovasc Eng Technol       Date:  2014-03-01       Impact factor: 2.495

3.  Numerical model of full-cardiac cycle hemodynamics in a total artificial heart and the effect of its size on platelet activation.

Authors:  Gil Marom; Wei-Che Chiu; Jessica R Crosby; Katrina J DeCook; Saurabh Prabhakar; Marc Horner; Marvin J Slepian; Danny Bluestein
Journal:  J Cardiovasc Transl Res       Date:  2014-10-30       Impact factor: 4.132

4.  Flow visualization of a pediatric ventricular assist device during stroke volume reductions related to weaning.

Authors:  Breigh N Roszelle; Steven Deutsch; William J Weiss; Keefe B Manning
Journal:  Ann Biomed Eng       Date:  2011-03-15       Impact factor: 3.934

5.  Platelet adhesion to polyurethane urea under pulsatile flow conditions.

Authors:  Michael A Navitsky; Joshua O Taylor; Alexander B Smith; Margaret J Slattery; Steven Deutsch; Christopher A Siedlecki; Keefe B Manning
Journal:  Artif Organs       Date:  2014-04-09       Impact factor: 3.094

6.  Validation of a non-conforming monolithic fluid-structure interaction method using phase-contrast MRI.

Authors:  Andreas Hessenthaler; Oliver Röhrle; David Nordsletten
Journal:  Int J Numer Method Biomed Eng       Date:  2017-02-16       Impact factor: 2.747

7.  Experiment for validation of fluid-structure interaction models and algorithms.

Authors:  A Hessenthaler; N R Gaddum; O Holub; R Sinkus; O Röhrle; D Nordsletten
Journal:  Int J Numer Method Biomed Eng       Date:  2017-01-27       Impact factor: 2.747

Review 8.  Innovative Modeling Techniques and 3D Printing in Patients with Left Ventricular Assist Devices: A Bridge from Bench to Clinical Practice.

Authors:  Rishi Thaker; Raquel Araujo-Gutierrez; Hernan G Marcos-Abdala; Tanushree Agrawal; Nadia Fida; Mahwash Kassi
Journal:  J Clin Med       Date:  2019-05-09       Impact factor: 4.241

9.  Device Thrombogenicity Emulation: An In Silico Predictor of In Vitro and In Vivo Ventricular Assist Device Thrombogenicity.

Authors:  Wei Che Chiu; Phat L Tran; Zain Khalpey; Eric Lee; Yi-Ren Woo; Marvin J Slepian; Danny Bluestein
Journal:  Sci Rep       Date:  2019-02-27       Impact factor: 4.379

10.  Methods for determination of stagnation in pneumatic ventricular assist devices.

Authors:  Damian Obidowski; Piotr Reorowicz; Dariusz Witkowski; Krzysztof Sobczak; Krzysztof Jóźwik
Journal:  Int J Artif Organs       Date:  2018-08-03       Impact factor: 1.595

  10 in total

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