BACKGROUND: The objective of this study was to determine how subjects responded to alarms for hypo- and hyperglycemia while they were sleeping. RESEARCH DESIGN AND METHODS: Twenty subjects with type 1 diabetes (4-17 years old) were admitted to a clinical research center for approximately 24 h. Each subject wore two GlucoWatch G2 Biographers (GW2B) (Cygnus, Inc., Redwood City, CA) and was videotaped using an infrared camera from 9 p.m. to 7 a.m. The videotapes were reviewed to determine if the GW2B alarms were audible on the tape and to document the subject's response to the alarms. Because many alarms can occur surrounding a change in blood glucose, GW2B alarm "events" are defined as a one or more alarms separated from previous alarms by more than 30 min. RESULTS: Downloaded data from the biographers identified 240 individual alarms, 75% of which occurred while the subject was sleeping. Of the 240 alarms 68% were audible on the videotape. Subjects awoke to 29% of individual alarms and to 66% of alarm events. Subjects 4-6 years old responded to 17% of alarms, 7-11 year olds responded to 20% of alarms, adolescents responded to 53% of alarms, and parents responded to 37% of alarms. Subjects awoke to 40% of the first alarm during the night, but to only 28% of subsequent alarms. There were 11 events when the glucose was confirmed to be < or = 70 mg/dL, and in each case the subject was awoken. Fifty-five percent of alarm events occurred when there was no hypo- or hyperglycemia confirmed by a reference glucose value. CONCLUSIONS: Subjects awoke to 29% of individual alarms and to 66% of alarm events. Subjects awoke during all alarm events when hypoglycemia was confirmed, but there was a high incidence of false alarms.
BACKGROUND: The objective of this study was to determine how subjects responded to alarms for hypo- and hyperglycemia while they were sleeping. RESEARCH DESIGN AND METHODS: Twenty subjects with type 1 diabetes (4-17 years old) were admitted to a clinical research center for approximately 24 h. Each subject wore two GlucoWatch G2 Biographers (GW2B) (Cygnus, Inc., Redwood City, CA) and was videotaped using an infrared camera from 9 p.m. to 7 a.m. The videotapes were reviewed to determine if the GW2B alarms were audible on the tape and to document the subject's response to the alarms. Because many alarms can occur surrounding a change in blood glucose, GW2B alarm "events" are defined as a one or more alarms separated from previous alarms by more than 30 min. RESULTS: Downloaded data from the biographers identified 240 individual alarms, 75% of which occurred while the subject was sleeping. Of the 240 alarms 68% were audible on the videotape. Subjects awoke to 29% of individual alarms and to 66% of alarm events. Subjects 4-6 years old responded to 17% of alarms, 7-11 year olds responded to 20% of alarms, adolescents responded to 53% of alarms, and parents responded to 37% of alarms. Subjects awoke to 40% of the first alarm during the night, but to only 28% of subsequent alarms. There were 11 events when the glucose was confirmed to be < or = 70 mg/dL, and in each case the subject was awoken. Fifty-five percent of alarm events occurred when there was no hypo- or hyperglycemia confirmed by a reference glucose value. CONCLUSIONS: Subjects awoke to 29% of individual alarms and to 66% of alarm events. Subjects awoke during all alarm events when hypoglycemia was confirmed, but there was a high incidence of false alarms.
Authors: H Peter Chase; Mary D Roberts; Clare Wightman; Georgeanna Klingensmith; Satish K Garg; Michelle Van Wyhe; Shashi Desai; Wesley Harper; Margarita Lopatin; Miroslaw Bartkowiak; Janet Tamada; Richard C Eastman Journal: Pediatrics Date: 2003-04 Impact factor: 7.124
Authors: Laura M Gandrud; Helen U Paguntalan; M Michelle Van Wyhe; Betsy L Kunselman; Amy D Leptien; Darrell M Wilson; Richard C Eastman; Bruce A Buckingham Journal: Pediatrics Date: 2004-01 Impact factor: 7.124
Authors: Fraser Cameron; Darrell M Wilson; Bruce A Buckingham; Hasmik Arzumanyan; Paula Clinton; H Peter Chase; John Lum; David M Maahs; Peter M Calhoun; B Wayne Bequette Journal: J Diabetes Sci Technol Date: 2012-09-01
Authors: Eyal Dassau; Fraser Cameron; Hyunjin Lee; B Wayne Bequette; Howard Zisser; Lois Jovanovic; H Peter Chase; Darrell M Wilson; Bruce A Buckingham; Francis J Doyle Journal: Diabetes Care Date: 2010-06 Impact factor: 17.152
Authors: Bruce Buckingham; H Peter Chase; Eyal Dassau; Erin Cobry; Paula Clinton; Victoria Gage; Kimberly Caswell; John Wilkinson; Fraser Cameron; Hyunjin Lee; B Wayne Bequette; Francis J Doyle Journal: Diabetes Care Date: 2010-03-03 Impact factor: 19.112