Literature DB >> 7715569

The 200-MeV proton therapy project at the Paul Scherrer Institute: conceptual design and practical realization.

E Pedroni1, R Bacher, H Blattmann, T Böhringer, A Coray, A Lomax, S Lin, G Munkel, S Scheib, U Schneider.   

Abstract

The new proton therapy facility is being assembled at the Paul Scherrer Institute (PSI). The beam delivered by the PSI sector cyclotron can be split and brought into a new hall where it is degraded from 590 MeV down to an energy in the range of 85-270 MeV. A new beam line following the degrader is used to clean the low-energetic beam in phase space and momentum band. The analyzed beam is then injected into a compact isocentric gantry, where it is applied to the patient using a new dynamic treatment modality, the so-called spot-scanning technique. This technique will permit full three-dimensional conformation of the dose to the target volume to be realized in a routine way without the need for individualized patient hardware like collimators and compensators. By combining the scanning of the focused pencil beam within the beam optics of the gantry and by mounting the patient table eccentrically on the gantry, the diameter of the rotating structure has been reduced to only 4 m. In the article the degrees of freedom available on the gantry to apply the beam to the patient (with two rotations for head treatments) are also discussed. The devices for the positioning of the patient on the gantry (x rays and proton radiography) and outside the treatment room (the patient transporter system and the modified mechanics of the computer tomograph unit) are briefly presented. The status of the facility and first experimental results are introduced for later reference.

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Year:  1995        PMID: 7715569     DOI: 10.1118/1.597522

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  68 in total

1.  Initial experience of using an active beam delivery technique at PSI.

Authors:  E Pedroni; T Böhringer; A Coray; E Egger; M Grossmann; S Lin; A Lomax; G Goitein; W Roser; B Schaffner
Journal:  Strahlenther Onkol       Date:  1999-06       Impact factor: 3.621

2.  An MCNPX Monte Carlo model of a discrete spot scanning proton beam therapy nozzle.

Authors:  Gabriel O Sawakuchi; Dragan Mirkovic; Luis A Perles; Narayan Sahoo; X Ron Zhu; George Ciangaru; Kazumichi Suzuki; Michael T Gillin; Radhe Mohan; Uwe Titt
Journal:  Med Phys       Date:  2010-09       Impact factor: 4.071

3.  Adjustment of the lateral and longitudinal size of scanned proton beam spots using a pre-absorber to optimize penumbrae and delivery efficiency.

Authors:  Uwe Titt; Dragan Mirkovic; Gabriel O Sawakuchi; Luis A Perles; Wayne D Newhauser; Phillip J Taddei; Radhe Mohan
Journal:  Phys Med Biol       Date:  2010-11-12       Impact factor: 3.609

4.  Four-dimensional radiotherapeutic dose calculation using biomechanical respiratory motion description.

Authors:  Petru Manescu; Hamid Ladjal; Joseph Azencot; Michael Beuve; Etienne Testa; Behzad Shariat
Journal:  Int J Comput Assist Radiol Surg       Date:  2013-09-01       Impact factor: 2.924

5.  Radiotherapy in ophthalmology : 2004 Jules Gonin lecture of the Retina Research Foundation.

Authors:  Leonidas Zografos
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2006-07       Impact factor: 3.117

6.  Quality assurance evaluation of spot scanning beam proton therapy with an anthropomorphic prostate phantom.

Authors:  K Iqbal; M Gillin; P A Summers; S Dhanesar; K A Gifford; S A Buzdar
Journal:  Br J Radiol       Date:  2013-09-18       Impact factor: 3.039

7.  Comparison of intensity modulated x-ray therapy and intensity modulated proton therapy for selective subvolume boosting: a phantom study.

Authors:  R T Flynn; D L Barbee; T R Mackie; R Jeraj
Journal:  Phys Med Biol       Date:  2007-10-01       Impact factor: 3.609

8.  Intensity modulated proton therapy.

Authors:  H M Kooy; C Grassberger
Journal:  Br J Radiol       Date:  2015-05-27       Impact factor: 3.039

9.  Evaluation of energy deposition and secondary particle production in proton therapy of brain using a slab head phantom.

Authors:  Sayyed Bijan Jia; Mohammad Hadi Hadizadeh; Ali Asghar Mowlavi; Mahdy Ebrahimi Loushab
Journal:  Rep Pract Oncol Radiother       Date:  2014-05-01

10.  Heavy-ion conformal irradiation in the shallow-seated tumor therapy terminal at HIRFL.

Authors:  Qiang Li; Zhongying Dai; Zheng Yan; Xiaodong Jin; Xinguo Liu; Guoqing Xiao
Journal:  Med Biol Eng Comput       Date:  2007-09-19       Impact factor: 2.602

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