Literature DB >> 6245152

Effects of Clostridium difficile toxin on tissue-cultured cells.

S T Donta, S J Shaffer.   

Abstract

A partially purified toxin of Clostridium difficile induced similar morphologic changes in three different tissue-cultured mammalian cell lines. The morphologic changes were not associated with biochemical changes indentical to those caused by the enterotoxins of Vibrio cholerae and Escherichia coli. Although the mechanisms responsible for the noncytotoxic morphologic effects remain to be delineated, the toxin appears to exert its effects by directly affecting membrane constituents.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6245152     DOI： 10.1093/infdis/141.2.218

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   5.226


  21 in total

1.  Use of pulsed-field gel electrophoresis for investigation of an outbreak of Clostridium difficile infection among geriatric patients.

Authors:  D Talon; P Bailly; M Delmée; M Thouverez; B Mulin; M Iehl-Robert; V Cailleaux; Y Michel-Briand
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1995-11       Impact factor: 3.267

2.  Cytotoxic effects of a leukocidin from Fusobacterium necrophorum on bovine hepatic cells.

Authors:  T Ishii; M Kanoe; T Inoue; K Kai; H Blobel
Journal:  Med Microbiol Immunol       Date:  1988       Impact factor: 3.402

3.  Effects of Clostridium difficile toxins A and B in rabbit small and large intestine in vivo and on cultured cells in vitro.

Authors:  A A Lima; D M Lyerly; T D Wilkins; D J Innes; R L Guerrant
Journal:  Infect Immun       Date:  1988-03       Impact factor: 3.441

4.  Nutritional aspects of cytotoxin production by Clostridium difficile.

Authors:  D P Osgood; N P Wood; J F Sperry
Journal:  Appl Environ Microbiol       Date:  1993-12       Impact factor: 4.792

5.  Production of antitoxins to two toxins of Clostridium difficile and immunological comparison of the toxins by cross-neutralization studies.

Authors:  J M Libby; T D Wilkins
Journal:  Infect Immun       Date:  1982-01       Impact factor: 3.441

6.  Clostridium difficile toxin-induced intestinal secretion in rabbit ileum in vitro.

Authors:  S Hughes; G Warhurst; L A Turnberg; N B Higgs; L G Giugliano; B S Drasar
Journal:  Gut       Date:  1983-02       Impact factor: 23.059

7.  Biological activities of toxins A and B of Clostridium difficile.

Authors:  D M Lyerly; D E Lockwood; S H Richardson; T D Wilkins
Journal:  Infect Immun       Date:  1982-03       Impact factor: 3.441

8.  Investigation of an outbreak of Clostridium difficile infection in a general hospital by numerical analysis of protein patterns by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

Authors:  M Costas; B Holmes; S L On; M Ganner; M C Kelly; S K Nath
Journal:  J Clin Microbiol       Date:  1994-03       Impact factor: 5.948

9.  Relative frequency of Clostridium difficile in patients with diarrheal disease.

Authors:  P H Gilligan; L R McCarthy; V M Genta
Journal:  J Clin Microbiol       Date:  1981-07       Impact factor: 5.948

10.  Detection of Clostridium difficile toxin with McCoy cell monolayers and cell suspensions and comparison with HeLa cell assay.

Authors:  A C Maniar; H Chubb; T J Louie; T W Williams; W Forsyth; J C Wilt
Journal:  J Clin Microbiol       Date:  1984-02       Impact factor: 5.948
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.