Literature DB >> 6172384

Production of antitoxins to two toxins of Clostridium difficile and immunological comparison of the toxins by cross-neutralization studies.

J M Libby, T D Wilkins.   

Abstract

We prepared antitoxins specific for each of two toxins of Clostridium difficile and used these to demonstrate that the toxins are immunologically distinct.

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Year:  1982        PMID: 6172384      PMCID: PMC351042          DOI: 10.1128/iai.35.1.374-376.1982

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  13 in total

1.  Effects of Clostridium difficile toxin on tissue-cultured cells.

Authors:  S T Donta; S J Shaffer
Journal:  J Infect Dis       Date:  1980-02       Impact factor: 5.226

2.  Clinical and laboratory observations in Clostridium difficile colitis.

Authors:  J G Bartlett; N S Taylor; T Chang; J Dzink
Journal:  Am J Clin Nutr       Date:  1980-11       Impact factor: 7.045

3.  Production of Clostridium difficile antitoxin.

Authors:  M Ehrich; R L Van Tassell; J M Libby; T D Wilkins
Journal:  Infect Immun       Date:  1980-06       Impact factor: 3.441

4.  Clindamycin-associated colitis due to a toxin-producing species of Clostridium in hamsters.

Authors:  J G Bartlett; A B Onderdonk; R L Cisneros; D L Kasper
Journal:  J Infect Dis       Date:  1977-11       Impact factor: 5.226

5.  Colitis induced by Clostridium difficile.

Authors:  J G Bartlett; T Chang; N S Taylor; A B Onderdonk
Journal:  Rev Infect Dis       Date:  1979 Mar-Apr

6.  Prevention of clindamycin-induced colitis in hamsters by Clostridium sordellii antitoxin.

Authors:  M Allo; J Silva; R Fekety; G D Rifkin; H Waskin
Journal:  Gastroenterology       Date:  1979-02       Impact factor: 22.682

Review 7.  Diarrhea and colitis associated with antimicrobial therapy in man and animals.

Authors:  W L George; R D Rolfe; V L Sutter; S M Finegold
Journal:  Am J Clin Nutr       Date:  1979-01       Impact factor: 7.045

8.  Clindamycin-induced enterocolitis in hamsters as a model of pseudomembranous colitis in patients.

Authors:  T W Chang; J G Bartlett; S L Gorbach; A B Onderdonk
Journal:  Infect Immun       Date:  1978-05       Impact factor: 3.441

9.  Purification and characterization of Clostridium difficile toxin.

Authors:  R D Rolfe; S M Finegold
Journal:  Infect Immun       Date:  1979-07       Impact factor: 3.441

10.  Mucosal damage mediated by clostridial toxin in experimental clindamycin-associated colitis.

Authors:  G D Abrams; M Allo; G D Rifkin; R Fekety; J Silva
Journal:  Gut       Date:  1980-06       Impact factor: 23.059

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  31 in total

1.  Development and evaluation of an ovine antibody-based platform for treatment of Clostridium difficile infection.

Authors:  April Roberts; Joanna McGlashan; Ibrahim Al-Abdulla; Roger Ling; Harriet Denton; Steve Green; Ruth Coxon; John Landon; Clifford Shone
Journal:  Infect Immun       Date:  2011-12-05       Impact factor: 3.441

2.  Monoclonal antibodies specific for Clostridium difficile toxin B and their use in immunoassays.

Authors:  F Müller; C Stiegler; U Hadding
Journal:  J Clin Microbiol       Date:  1992-06       Impact factor: 5.948

Review 3.  Toxigenic clostridia.

Authors:  C L Hatheway
Journal:  Clin Microbiol Rev       Date:  1990-01       Impact factor: 26.132

Review 4.  Vaccines against Clostridium difficile.

Authors:  Rosanna Leuzzi; Roberto Adamo; Maria Scarselli
Journal:  Hum Vaccin Immunother       Date:  2014-03-17       Impact factor: 3.452

5.  Characterization of toxins A and B of Clostridium difficile with monoclonal antibodies.

Authors:  D M Lyerly; C J Phelps; J Toth; T D Wilkins
Journal:  Infect Immun       Date:  1986-10       Impact factor: 3.441

Review 6.  Update on pseudomembranous colitis.

Authors:  J Silva
Journal:  West J Med       Date:  1989-12

7.  Mechanisms of protection against Clostridium difficile infection by the monoclonal antitoxin antibodies actoxumab and bezlotoxumab.

Authors:  Zhiyong Yang; Jeremy Ramsey; Therwa Hamza; Yongrong Zhang; Shan Li; Harris G Yfantis; Dong Lee; Lorraine D Hernandez; Wolfgang Seghezzi; Jamie M Furneisen; Nicole M Davis; Alex G Therien; Hanping Feng
Journal:  Infect Immun       Date:  2014-12-08       Impact factor: 3.441

8.  Enzyme immunoassay for detection of antibody to toxins A and B of Clostridium difficile.

Authors:  R P Viscidi; R H Yolken; B E Laughon; J G Bartlett
Journal:  J Clin Microbiol       Date:  1983-08       Impact factor: 5.948

9.  Evaluation of the usefulness of counterimmunoelectrophoresis for diagnosis of Clostridium difficile-associated colitis in clinical specimens.

Authors:  T C Wu; J C Fung
Journal:  J Clin Microbiol       Date:  1983-04       Impact factor: 5.948

10.  Binding kinetics of Clostridium difficile toxins A and B to intestinal brush border membranes from infant and adult hamsters.

Authors:  R D Rolfe
Journal:  Infect Immun       Date:  1991-04       Impact factor: 3.441

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