Literature DB >> 3340060

Cytotoxic effects of a leukocidin from Fusobacterium necrophorum on bovine hepatic cells.

T Ishii1, M Kanoe, T Inoue, K Kai, H Blobel.   

Abstract

Cytotoxic effects of a leukocidin from Fusobacterium necrophorum were demonstrated on bovine hepatic cells. The cytotoxic response was dose-dependent and could be inhibited by homologous antiserum. Scanning electron microscopy revealed damaged hepatic cell surface. These findings indicated a pathogenic role of the leukocidin in F. necrophorum infections.

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Year:  1988        PMID： 3340060     DOI： 10.1007/bf00190308

Source DB:  PubMed          Journal:  Med Microbiol Immunol        ISSN： 0300-8584            Impact factor:   3.402


  10 in total

1.  Staphylococcal leucocidins.

Authors:  G P GLADSTONE; W E VAN HEYNINGEN
Journal:  Br J Exp Pathol       Date:  1957-04

2.  Partial characterization of leukocidin from Fusobacterium necrophorum.

Authors:  M Kanoe; T Ishii; K Mizutani; H Blobel
Journal:  Zentralbl Bakteriol Mikrobiol Hyg A       Date:  1986-04

3.  Meningitis caused by Fusobacterium necrophorum.

Authors:  A Tärnvik; G Sundqvist; L Gothefors; H Gustafsson
Journal:  Eur J Clin Microbiol       Date:  1986-06       Impact factor: 3.267

4.  Correlations between leukocidin production and virulence of two isolates of Fusobacterium necrophorum.

Authors:  J E Coyle-Dennis; L H Lauerman
Journal:  Am J Vet Res       Date:  1979-02       Impact factor: 1.156

5.  Sphaerophorus necrophorus. A study of 23 strains.

Authors:  B Aalbaek
Journal:  Acta Vet Scand       Date:  1971       Impact factor: 1.695

6.  Effects of Fusobacterium necrophorum leukotoxin on rabbit peritoneal macrophages in vitro.

Authors:  W H Fales; J F Warner; G W Teresa
Journal:  Am J Vet Res       Date:  1977-04       Impact factor: 1.156

7.  Effects of Clostridium difficile toxin on tissue-cultured cells.

Authors:  S T Donta; S J Shaffer
Journal:  J Infect Dis       Date:  1980-02       Impact factor: 5.226

8.  Cytotoxicity of endotoxin in vitro. Effects on macrophages from normal guinea pigs.

Authors:  R W Kessel; W Braun
Journal:  Aust J Exp Biol Med Sci       Date:  1965-08

9.  The pathogenic synergy of Fusiformis necrophorus and Corynebacterium pyogenes. I. Influence of the leucocidal exotoxin of F. necrophorus.

Authors:  D S Roberts
Journal:  Br J Exp Pathol       Date:  1967-12

10.  Comparative in vitro leukotoxin production of three bovine strains of Fusobacterium necrophorum.

Authors:  C M Scanlan; J N Berg; W H Fales
Journal:  Am J Vet Res       Date:  1982-08       Impact factor: 1.156
  10 in total

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