Literature DB >> 6164931

[Prospects and limitations of genetic engineering].

W Klingmüller.   

Abstract

Examples for genetic engineering are the transfer of nuclei between cells of higher animals and the introduction of heterologous DNA into bacteria by means of plasmids. The former approach will help to establish new ways in animal breeding, the latter provides bacterial cells that produce proteins of medical importance. The moral justification of related studies in man is still open, but the possible risks of gene technology can be coped with by adhering to proper safety regulations.

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Year:  1981        PMID: 6164931     DOI: 10.1007/BF01047248

Source DB:  PubMed          Journal:  Naturwissenschaften        ISSN: 0028-1042


  11 in total

1.  Gentic engineering for practical application.

Authors:  W Klingmüller
Journal:  Naturwissenschaften       Date:  1979-04

2.  Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone.

Authors:  D V Goeddel; H L Heyneker; T Hozumi; R Arentzen; K Itakura; D G Yansura; M J Ross; G Miozzari; R Crea; P H Seeburg
Journal:  Nature       Date:  1979-10-18       Impact factor: 49.962

3.  Molecular biology: suffering from shock.

Authors: 
Journal:  Nature       Date:  1979-04-12       Impact factor: 49.962

4.  Expression in Escherichia coli of chemically synthesized genes for human insulin.

Authors:  D V Goeddel; D G Kleid; F Bolivar; H L Heyneker; D G Yansura; R Crea; T Hirose; A Kraszewski; K Itakura; A D Riggs
Journal:  Proc Natl Acad Sci U S A       Date:  1979-01       Impact factor: 11.205

5.  Expression of cloned beta-endorphin gene sequences by Escherichia coli.

Authors:  J Shine; I Fettes; N C Lan; J L Roberts; J D Baxter
Journal:  Nature       Date:  1980-06-12       Impact factor: 49.962

6.  Synthesis in E. coli of a polypeptide with human leukocyte interferon activity.

Authors:  S Nagata; H Taira; A Hall; L Johnsrud; M Streuli; J Ecsödi; W Boll; K Cantell; C Weissmann
Journal:  Nature       Date:  1980-03-27       Impact factor: 49.962

7.  Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin.

Authors:  K Itakura; T Hirose; R Crea; A D Riggs; H L Heyneker; F Bolivar; H W Boyer
Journal:  Science       Date:  1977-12-09       Impact factor: 47.728

8.  Human leukocyte interferon produced by E. coli is biologically active.

Authors:  D V Goeddel; E Yelverton; A Ullrich; H L Heyneker; G Miozzari; W Holmes; P H Seeburg; T Dull; L May; N Stebbing; R Crea; S Maeda; R McCandliss; A Sloma; J M Tabor; M Gross; P C Familletti; S Pestka
Journal:  Nature       Date:  1980-10-02       Impact factor: 49.962

9.  Influenza antigenic determinants are expressed from haemagglutinin genes cloned in Escherichia coli.

Authors:  J S Emtage; W C Tacon; G H Catlin; B Jenkins; A G Porter; N H Carey
Journal:  Nature       Date:  1980-01-10       Impact factor: 49.962

10.  Hepatitis B virus genes and their expression in E. coli.

Authors:  M Pasek; T Goto; W Gilbert; B Zink; H Schaller; P MacKay; G Leadbetter; K Murray
Journal:  Nature       Date:  1979-12-06       Impact factor: 49.962

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