Literature DB >> 386136

Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone.

D V Goeddel, H L Heyneker, T Hozumi, R Arentzen, K Itakura, D G Yansura, M J Ross, G Miozzari, R Crea, P H Seeburg.   

Abstract

DNA coding for human growth hormone was constructed by using chemically synthesised DNA in conjunction with enzymatically prepared cDNA. This 'hybrid' gene was expressed in Escherichia coli under the control of the lac promoter. A polypeptide was produced having the size and immunological properties characteristic of mature human growth hormone.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 386136     DOI： 10.1038/281544a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  73 in total

Review 1.  'Molecular farming' of antibodies in plants.

Authors:  Stefan Schillberg; Rainer Fischer; Neil Emans
Journal:  Naturwissenschaften       Date:  2003-02-18

2.  Optimization of cell culture conditions for production of biologically active proteins.

Authors:  S Hosoi; H Miyaji; M Satoh; T Kurimoto; A Mihara; N Fujiyoshi; S Itoh; S Sato
Journal:  Cytotechnology       Date:  1991-01       Impact factor: 2.058

3.  Stabilizing peptide fusion for solving the stability and solubility problems of therapeutic proteins.

Authors:  Eui Nam Lee; Young Mok Kim; Hye Ja Lee; Sang Woo Park; Han Young Jung; Jae Myun Lee; Yong-Ho Ahn; Jongsun Kim
Journal:  Pharm Res       Date:  2005-09-22       Impact factor: 4.200

Review 4.  Recombinant DNA and surgery.

Authors:  J M Brown; A H Harken; J B Sharefkin
Journal:  Ann Surg       Date:  1990-08       Impact factor: 12.969

Review 5.  Growth hormone, 1988.

Authors:  M O Thorner; M L Vance
Journal:  J Clin Invest       Date:  1988-09       Impact factor: 14.808

6.  Proteolytic processing of foot-and-mouth disease virus polyproteins expressed in a cell-free system from clone-derived transcripts.

Authors:  V N Vakharia; M A Devaney; D M Moore; J J Dunn; M J Grubman
Journal:  J Virol       Date:  1987-10       Impact factor: 5.103

Review 7.  Growth hormone - past, present and future.

Authors:  Michael B Ranke; Jan M Wit
Journal:  Nat Rev Endocrinol       Date:  2018-03-16       Impact factor: 43.330

8.  Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes.

Authors:  R D Palmiter; R L Brinster; R E Hammer; M E Trumbauer; M G Rosenfeld; N C Birnberg; R M Evans
Journal:  Nature       Date:  1982-12-16       Impact factor: 49.962

9.  Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli.

Authors:  S Cabilly; A D Riggs; H Pande; J E Shively; W E Holmes; M Rey; L J Perry; R Wetzel; H L Heyneker
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

10.  Managing idiopathic short stature: role of somatropin (rDNA origin) for injection.

Authors:  J Paul Frindik; Stephen F Kemp
Journal:  Biologics       Date:  2010-06-24
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.