Literature DB >> 399329

Hepatitis B virus genes and their expression in E. coli.

M Pasek, T Goto, W Gilbert, B Zink, H Schaller, P MacKay, G Leadbetter, K Murray.   

Abstract

A composite DNA sequence of regions of hepatitis B virus, determined from a series of recombinant plasmids, reveals the genes for the surface antigen and the core antigen of the virus. The sequence of the core antigen shows it to be a DNA binding protein. The core antigen gene is expressed in Escherichia coli and when injected into rabbits the bacterial product induces antibodies which react with core antigen isolated from human sources.

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Year:  1979        PMID： 399329     DOI： 10.1038/282575a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  208 in total

1.  Differential formation of disulfide linkages in the core antigen of extracellular and intracellular hepatitis B virus core particles.

Authors:  K S Jeng; C P Hu; C M Chang
Journal:  J Virol       Date:  1991-07       Impact factor: 5.103

2.  Tight clustering of human hepatitis B virus integration sites in hepatomas near a triple-stranded region.

Authors:  C Shih; K Burke; M J Chou; J B Zeldis; C S Yang; C S Lee; K J Isselbacher; J R Wands; H M Goodman
Journal:  J Virol       Date:  1987-11       Impact factor: 5.103

3.  Transcriptional trans-activating function of hepatitis B virus.

Authors:  J S Twu; R H Schloemer
Journal:  J Virol       Date:  1987-11       Impact factor: 5.103

4.  Complete nucleotide sequence of the polymerase 3 gene of human influenza virus A/WSN/33.

Authors:  J S Kaptein; D P Nayak
Journal:  J Virol       Date:  1982-04       Impact factor: 5.103

5.  Hepatitis B virus core antigen: synthesis in Escherichia coli and application in diagnosis.

Authors:  S Stahl; P MacKay; M Magazin; S A Bruce; K Murray
Journal:  Proc Natl Acad Sci U S A       Date:  1982-03       Impact factor: 11.205

6.  Hepatitis B core antigen synthesised in Escherichia coli: its use for antibody screening in patients attending a clinic for sexually transmitted diseases.

Authors:  B J Cohen; P A Litton; P P Mortimer; P Simmons
Journal:  J Hyg (Lond)       Date:  1984-10

7.  Distinct requirements for primary sequence in the 5'- and 3'-part of a bulge in the hepatitis B virus RNA encapsidation signal revealed by a combined in vivo selection/in vitro amplification system.

Authors:  A Rieger; M Nassal
Journal:  Nucleic Acids Res       Date:  1995-10-11       Impact factor: 16.971

8.  Definition of a minimal optimal cytotoxic T-cell epitope within the hepatitis B virus nucleocapsid protein.

Authors:  A Bertoletti; F V Chisari; A Penna; S Guilhot; L Galati; G Missale; P Fowler; H J Schlicht; A Vitiello; R C Chesnut
Journal:  J Virol       Date:  1993-04       Impact factor: 5.103

9.  Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B.

Authors:  C Boni; A Bertoletti; A Penna; A Cavalli; M Pilli; S Urbani; P Scognamiglio; R Boehme; R Panebianco; F Fiaccadori; C Ferrari
Journal:  J Clin Invest       Date:  1998-09-01       Impact factor: 14.808

Review 10.  Revisiting Hepatitis B Virus: Challenges of Curative Therapies.

Authors:  Jianming Hu; Ulrike Protzer; Aleem Siddiqui
Journal:  J Virol       Date:  2019-09-30       Impact factor: 5.103
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