Literature DB >> 4589896

The requirement for ribosomal proteins L7 and L12 in peptide-chain termination.

N Brot, W P Tate, C T Caskey, H Weissbach.   

Abstract

Proteins L7 and L12 from 50S ribosomal subunits of Escherichia coli are required for peptidechain termination. This termination process is inhibited by thiostrepton. Since both thiostrepton-treated ribosomes and those depleted of L7 and L12 have a markedly reduced ability to form release factor.UA[(3)H]A.ribosome complexes, the binding of release factors to the ribosome appears to be the primary site of inhibition.

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Year:  1974        PMID： 4589896      PMCID： PMC387938          DOI： 10.1073/pnas.71.1.89

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  36 in total

1.  Inhibition by thiostrepton of the formation of a ribosome-bound guanine nucleotide complex.

Authors:  B Weisblum; V Demohn
Journal:  FEBS Lett       Date:  1970-12       Impact factor: 4.124

2.  Inability of E. coli ribosomes to interact simultaneously with the bacterial elongation factors EF Tu and EF G.

Authors:  D Richter
Journal:  Biochem Biophys Res Commun       Date:  1972-03-10       Impact factor: 3.575

3.  Reconstitution of a GTPase activity by a 50S ribosomal protein and E. coli.

Authors:  K Kischa; W Möller; G Stöffler
Journal:  Nat New Biol       Date:  1971-09-08

4.  Peptide chain termination. VII. The ribosomal and release factor requirements for peptide release.

Authors:  R K Tompkins; E M Scolnick; C T Caskey
Journal:  Proc Natl Acad Sci U S A       Date:  1970-03       Impact factor: 11.205

5.  Regulatory mechanisms and protein synthesis. X. Codon recognition on 30 S ribosomes.

Authors:  S Pestka; M Nirenberg
Journal:  J Mol Biol       Date:  1966-10-28       Impact factor: 5.469

6.  Peptide chain termination: effect of protein S on ribosomal binding of release factors.

Authors:  J L Goldstein; C T Caskey
Journal:  Proc Natl Acad Sci U S A       Date:  1970-10       Impact factor: 11.205

7.  Inhibition by thiopeptin of ribosomal functions associated with T and G factors.

Authors:  T Kinoshita; Y Liou; N Tanaka
Journal:  Biochem Biophys Res Commun       Date:  1971-08-20       Impact factor: 3.575

8.  Sequential translation of trinucleotide codons for the initiation and termination of protein synthesis.

Authors:  C T Caskey; R Tompkins; E Scolnick; T Caryk; M Nirenberg
Journal:  Science       Date:  1968-10-04       Impact factor: 47.728

9.  Mammalian peptide chain termination. II. Codon specificity and GTPase activity of release factor.

Authors:  A L Beaudet; C T Caskey
Journal:  Proc Natl Acad Sci U S A       Date:  1971-03       Impact factor: 11.205

10.  Inhibition by siomycin and thiostrepton of both aminoacyl-tRNA and factor G binding to ribosomes.

Authors:  J Modolell; B Cabrer; A Parmeggiani; D Vazquez
Journal:  Proc Natl Acad Sci U S A       Date:  1971-08       Impact factor: 11.205
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  19 in total

1.  Mutations in the GTPase center of Escherichia coli 23S rRNA indicate release factor 2-interactive sites.

Authors:  Wenbing Xu; Frances T Pagel; Emanuel J Murgola
Journal:  J Bacteriol       Date:  2002-02       Impact factor: 3.490

2.  Release factor RF-3 GTPase activity acts in disassembly of the ribosome termination complex.

Authors:  G Grentzmann; P J Kelly; S Laalami; M Shuda; M A Firpo; Y Cenatiempo; A Kaji
Journal:  RNA       Date:  1998-08       Impact factor: 4.942

3.  Mutations in RNAs of both ribosomal subunits cause defects in translation termination.

Authors:  A L Arkov; D V Freistroffer; M Ehrenberg; E J Murgola
Journal:  EMBO J       Date:  1998-03-02       Impact factor: 11.598

4.  Evolution of the protein stoichiometry in the L12 stalk of bacterial and organellar ribosomes.

Authors:  Iakov I Davydov; Ingo Wohlgemuth; Irena I Artamonova; Henning Urlaub; Alexander G Tonevitsky; Marina V Rodnina
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

5.  Ribosomal protein L7/L12 is required for GTPase translation factors EF-G, RF3, and IF2 to bind in their GTP state to 70S ribosomes.

Authors:  Markus A Carlson; Bassam G Haddad; Amanda J Weis; Colby S Blackwood; Catherine D Shelton; Michelle E Wuerth; Justin D Walter; Paul Clint Spiegel
Journal:  FEBS J       Date:  2017-04-10       Impact factor: 5.542

6.  Oxidation of the methionine residues of Escherichia coli ribosomal protein L12 decreases the protein's biological activity.

Authors:  P Caldwell; D C Luk; H Weissbach; N Brot
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

7.  Temperature-dependent variation in the extent of methylation of ribosomal proteins L7 and L12 in Escherichia coli.

Authors:  F N Chang
Journal:  J Bacteriol       Date:  1978-09       Impact factor: 3.490

8.  Genetic and biochemical characterization of a ribosomal mutant of Bacillus subtilis resistant to sporangiomycin.

Authors:  M Bazzicalupo; B Parisi; G Pirali; M Polsinelli; F Sala
Journal:  Antimicrob Agents Chemother       Date:  1975-12       Impact factor: 5.191

9.  Thiostrepton-resistant mutants of Bacillus subtilis: localization of resistance to the 50S subunit.

Authors:  S Pestka; D Weiss; R Vince; B Wienen; G Stöffler; I Smith
Journal:  Mol Gen Genet       Date:  1976-03-30

10.  Binding of thiostrepton to ribosomes from thiostrepton-sensitive and -resistant Bacillus subtilis strains.

Authors:  R Vince; D Weiss; J Gordon; G Howard; I Smith; S Pestka
Journal:  Antimicrob Agents Chemother       Date:  1976-04       Impact factor: 5.191
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