Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Mammalian peptide chain termination. II. Codon specificity and GTPase activity of release factor.

Literature DB >> 5276771

Mammalian peptide chain termination. II. Codon specificity and GTPase activity of release factor.

Abstract

In vitro peptide chain termination with release factor preparations from rabbit reticulocytes, guinea pig liver, or Chinese hamster liver is directed with UAAA, UAGA, or UGAA, suggesting that UAA, UAG, and UGA are terminator condons for mammalian cells. Purified release factor from rabbit reticulocytes has ribosomaldependent GTPase activity, which is stimulated by UAAA. GTP hydrolysis appears requisite for in vitro peptide chain termination in mammals.

Entities: Chemical Species

Mesh：

Substances：

Year: 1971 PMID： 5276771 PMCID： PMC389002 DOI： 10.1073/pnas.68.3.619

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

23 in total

1. Synthesis of trinucleoside diphosphates with polynucleotide phosphorylase.

Authors: P Leder; M F Singer; R L Brimacombe
Journal: Biochemistry Date: 1965-08 Impact factor: 3.162

2. Release factors differing in specificity for terminator codons.

Authors: E Scolnick; R Tompkins; T Caskey; M Nirenberg
Journal: Proc Natl Acad Sci U S A Date: 1968-10 Impact factor: 11.205

3. The role of guanosine 5'-triphosphate in the initiation of peptide synthesis. 3. Binding of formylmethionyl-tRNA to ribosomes.

Authors: T Ohta; S Sarkar; R E Thach
Journal: Proc Natl Acad Sci U S A Date: 1967-10 Impact factor: 11.205

4. Demonstration of a guanosine triphosphate-dependent enzymatic binding of aminoacyl-ribonucleic acid to Escherichia coli ribosomes.

Authors: J M Ravel
Journal: Proc Natl Acad Sci U S A Date: 1967-06 Impact factor: 11.205

5. Studies on polynucleotides. LXXXIX. A study of amino acid incorporation in a reticulocyte cell-free protein-synthesizing system with polyribonucleotides with repeating nucleotide sequences used as messengers.

Authors: N K Gupta
Journal: J Biol Chem Date: 1968-10-10 Impact factor: 5.157

6. A simple method for the preparation of 32-P-labelled adenosine triphosphate of high specific activity.

Authors: I M Glynn; J B Chappell
Journal: Biochem J Date: 1964-01 Impact factor: 3.857

7. Guanosine 5'-triphosphatase activity of initiation factor f2.

Authors: D Kolakofsky; K F Dewey; J W Hershey; R E Thach
Journal: Proc Natl Acad Sci U S A Date: 1968-11 Impact factor: 11.205

8. Sequential translation of trinucleotide codons for the initiation and termination of protein synthesis.

Authors: C T Caskey; R Tompkins; E Scolnick; T Caryk; M Nirenberg
Journal: Science Date: 1968-10-04 Impact factor: 47.728

9. Fine structure of RNA codewords recognized by bacterial, amphibian, and mammalian transfer RNA.

Authors: R E Marshall; C T Caskey; M Nirenberg
Journal: Science Date: 1967-02-17 Impact factor: 47.728

10. Estimation of the molecular weights of proteins by Sephadex gel-filtration.

Authors: P Andrews
Journal: Biochem J Date: 1964-05 Impact factor: 3.766

17 in total

1. Cloning and expression of a mammalian peptide chain release factor with sequence similarity to tryptophanyl-tRNA synthetases.

Authors: C C Lee; W J Craigen; D M Muzny; E Harlow; C T Caskey
Journal: Proc Natl Acad Sci U S A Date: 1990-05 Impact factor: 11.205

2. Eukaryotic release factor 1 (eRF1) abolishes readthrough and competes with suppressor tRNAs at all three termination codons in messenger RNA.

Authors: G Drugeon; O Jean-Jean; L Frolova; X Le Goff; M Philippe; L Kisselev; A L Haenni
Journal: Nucleic Acids Res Date: 1997-06-15 Impact factor: 16.971

3. The requirement for ribosomal proteins L7 and L12 in peptide-chain termination.

Authors: N Brot; W P Tate; C T Caskey; H Weissbach
Journal: Proc Natl Acad Sci U S A Date: 1974-01 Impact factor: 11.205

Review 4. The mechanism of peptide chain termination.

Authors: W P Tate; C T Caskey
Journal: Mol Cell Biochem Date: 1974-12-20 Impact factor: 3.396

5. Structure and function of tryptophan tRNA from wheat germ.

Authors: K Ghosh; H P Ghosh
Journal: Nucleic Acids Res Date: 1984-06-25 Impact factor: 16.971

Review 6. Termination of protein synthesis.

Authors: M F Tuite; I Stansfield
Journal: Mol Biol Rep Date: 1994-05 Impact factor: 2.316