Literature DB >> 817664

Binding of thiostrepton to ribosomes from thiostrepton-sensitive and -resistant Bacillus subtilis strains.

R Vince, D Weiss, J Gordon, G Howard, I Smith, S Pestka.   

Abstract

Binding of [(35)S]thiostrepton to ribosomes from thiostrepton-sensitive and -resistant strains of Bacillus subtilis was studied. Ribosomes from thiostrepton-resistant strains bound relatively little thiostrepton compared with ribosomes from thiostrepton-sensitive B. subtilis. In addition, ribosomes from revertant strains that were obtained as thiostrepton-sensitive revertants from thiostrepton-resistant strains bound [(35)S]thiostrepton similarly to ribosomes from the sensitive parental strain.

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Year:  1976        PMID: 817664      PMCID: PMC429595          DOI: 10.1128/AAC.9.4.665

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  22 in total

1.  Modes of action of erythromycin and thiostrepton as inhibitors of protein synthesis.

Authors:  Michael Cannon; Kay Burns
Journal:  FEBS Lett       Date:  1971-10-15       Impact factor: 4.124

2.  Inhibition by thiostrepton of the formation of a ribosome-bound guanine nucleotide complex.

Authors:  B Weisblum; V Demohn
Journal:  FEBS Lett       Date:  1970-12       Impact factor: 4.124

3.  Thiostrepton: a ribosomal inhibitor of translocation.

Authors:  S Pestka
Journal:  Biochem Biophys Res Commun       Date:  1970-08-11       Impact factor: 3.575

4.  Relation between the ribosomal sites involved in initiation and elongation of polypeptide chains. Evidence for two guanosine triphosphatase sites.

Authors:  A H Lockwood; U Maitra
Journal:  J Biol Chem       Date:  1974-01-25       Impact factor: 5.157

Review 5.  Inhibitors of ribosome functions.

Authors:  S Pestka
Journal:  Annu Rev Microbiol       Date:  1971       Impact factor: 15.500

6.  Inhibition by thiopeptin of ribosomal functions associated with T and G factors.

Authors:  T Kinoshita; Y Liou; N Tanaka
Journal:  Biochem Biophys Res Commun       Date:  1971-08-20       Impact factor: 3.575

7.  Effect of siomycin on the acceptor site of Escherichia coli ribosomes.

Authors:  S Watanabe; K Tanaka
Journal:  Biochem Biophys Res Commun       Date:  1971-11-05       Impact factor: 3.575

8.  Identification of a ribosomal protein necessary for thiostrepton binding to Escherichia coli ribosomes.

Authors:  J H Highland; G A Howard; E Ochsner; R Hasenbank; J Gordon; G Stöffler
Journal:  J Biol Chem       Date:  1975-02-10       Impact factor: 5.157

9.  Thiostrepton-resistant mutants of Bacillus subtilis: localization of resistance to the 50S subunit.

Authors:  S Pestka; D Weiss; R Vince; B Wienen; G Stöffler; I Smith
Journal:  Mol Gen Genet       Date:  1976-03-30

10.  Inhibition by siomycin and thiostrepton of both aminoacyl-tRNA and factor G binding to ribosomes.

Authors:  J Modolell; B Cabrer; A Parmeggiani; D Vazquez
Journal:  Proc Natl Acad Sci U S A       Date:  1971-08       Impact factor: 11.205

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  2 in total

1.  Thiostrepton-resistant mutants exhibit relaxed synthesis of RNA.

Authors:  I Smith; P Paress; S Pestka
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

2.  Thiostrepton-resistant mutants of Bacillus subtilis: localization of resistance to the 50S subunit.

Authors:  S Pestka; D Weiss; R Vince; B Wienen; G Stöffler; I Smith
Journal:  Mol Gen Genet       Date:  1976-03-30
  2 in total

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