| Literature DB >> 4000938 |
S W Wang, A J Robins, R d'Andrea, J R Wells.
Abstract
Sequence analysis of an 8.4 kb fragment containing five chicken histone genes shows that an H4-H2A gene pair is duplicated and inverted around a central H3 gene. A left and right region, each of 2.1 kb are 97% homologous and the boundaries of homology coincide with ten base pair repeats. These boundary regions also contain highly conserved gene promoter elements, suggesting that interaction of transcriptional machinery with histone genes may be connected with recombination in promoter regions, resulting in the inverted duplication structure seen in this cluster.Entities:
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Year: 1985 PMID: 4000938 PMCID: PMC341078 DOI: 10.1093/nar/13.4.1369
Source DB: PubMed Journal: Nucleic Acids Res ISSN: 0305-1048 Impact factor: 16.971