The role of joint receptors in human kinaesthesia when intramuscular receptors cannot contribute.

1. Kinaesthetic acuity was tested at the distal interphalangeal joint of the middle finger when the hand was postured so that the joint was effectively disengaged from its muscular attachments. Subjects were required to detect the direction of 5 deg movements applied at different angular velocities from a mid-position under control conditions, after intra-articular injection of a plasma expander and after intra-articular injection of a local anaesthetic. 2. Kinaesthetic performance was enhanced after the injection of a plasma expander and deteriorated after injection of local anaesthetic. This deterioration could not be explained by spread of the local anaesthesic from the injection site on the dorsum of the joint. 3. The results suggest that the discharge of joint receptors can produce perceived signals of joint movement. Under normal conditions these receptors may duplicate the kinaesthetic input from muscle spindle endings.