Stefaan Vandenberghe1, Nicolas A Karakatsanis2, Maya Abi Akl3,4, Jens Maebe3, Suleman Surti5, Rudi A Dierckx6, Daniel A Pryma5, Sadek A Nehmeh2, Othmane Bouhali4, Joel S Karp5. 1. Medical Image and Signal Processing, Ghent University, Corneel Heymans Laan 10, 9000, Ghent, Belgium. stefaan.vandenberghe@ugent.be. 2. Weill Cornell Medical College, Cornell University, NY, USA. 3. Medical Image and Signal Processing, Ghent University, Corneel Heymans Laan 10, 9000, Ghent, Belgium. 4. Science Program, Texas A&M University at Qatar, Doha, Qatar. 5. Department of Radiology, University of Pennsylvania, Philadelphia, USA. 6. Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Abstract
PURPOSE: Total body positron emission tomography (TB-PET) has recently been introduced in nuclear medicine departments. There is a large interest in these systems, but for many centers, the high acquisition cost makes it very difficult to justify their current operational budget. Here, we propose medium-cost long axial FOV scanners as an alternative. METHODS: Several medium-cost long axial FOV designs are described with their advantages and drawbacks. We describe their potential for higher throughput, more cost-effective scanning, a larger group of indications, and novel research opportunities. The wider spread of TB-PET can also lead to the fast introduction of new tracers (at a low dose), new methodologies, and optimized workflows. CONCLUSIONS: A medium-cost TB-PET would be positioned between the current standard PET-CT and the full TB-PET systems in investment but recapitulate most advantages of full TB-PET. These systems could be more easily justified financially in a standard academic or large private nuclear medicine department and still have ample research options.
PURPOSE: Total body positron emission tomography (TB-PET) has recently been introduced in nuclear medicine departments. There is a large interest in these systems, but for many centers, the high acquisition cost makes it very difficult to justify their current operational budget. Here, we propose medium-cost long axial FOV scanners as an alternative. METHODS: Several medium-cost long axial FOV designs are described with their advantages and drawbacks. We describe their potential for higher throughput, more cost-effective scanning, a larger group of indications, and novel research opportunities. The wider spread of TB-PET can also lead to the fast introduction of new tracers (at a low dose), new methodologies, and optimized workflows. CONCLUSIONS: A medium-cost TB-PET would be positioned between the current standard PET-CT and the full TB-PET systems in investment but recapitulate most advantages of full TB-PET. These systems could be more easily justified financially in a standard academic or large private nuclear medicine department and still have ample research options.
Authors: Nicolas A Karakatsanis; Martin A Lodge; Abdel K Tahari; Y Zhou; Richard L Wahl; Arman Rahmim Journal: Phys Med Biol Date: 2013-09-30 Impact factor: 3.609
Authors: George A Prenosil; Hasan Sari; Markus Fürstner; Ali Afshar-Oromieh; Kuangyu Shi; Axel Rominger; Michael Hentschel Journal: J Nucl Med Date: 2021-07-22 Impact factor: 10.057
Authors: Benjamin A Spencer; Eric Berg; Jeffrey P Schmall; Negar Omidvari; Edwin K Leung; Yasser G Abdelhafez; Songsong Tang; Zilin Deng; Yun Dong; Yang Lv; Jun Bao; Weiping Liu; Hongdi Li; Terry Jones; Ramsey D Badawi; Simon R Cherry Journal: J Nucl Med Date: 2020-10-02 Impact factor: 10.057
Authors: Joel S Karp; Varsha Viswanath; Michael J Geagan; Gerd Muehllehner; Austin R Pantel; Michael J Parma; Amy E Perkins; Jeffrey P Schmall; Matthew E Werner; Margaret E Daube-Witherspoon Journal: J Nucl Med Date: 2019-06-21 Impact factor: 11.082
Authors: Austin R Pantel; Varsha Viswanath; Margaret E Daube-Witherspoon; Jacob G Dubroff; Gerd Muehllehner; Michael J Parma; Daniel A Pryma; Erin K Schubert; David A Mankoff; Joel S Karp Journal: J Nucl Med Date: 2019-09-27 Impact factor: 11.082