Literature DB >> 3595565

Two highly polymorphic minisatellites from the pseudoautosomal region of the human sex chromosomes.

M C Simmler, C Johnsson, C Petit, F Rouyer, G Vergnaud, J Weissenbach.   

Abstract

Two pseudoautosomal loci DXYS15 and DXYS17 from the pairing region of the human sex chromosomes display a high variability with at least eight alleles each. The structural elements responsible for the polymorphisms have been isolated and sequenced. In both cases the variations result from DNA rearrangements occurring in tandemly repeated sequences (minisatellites) of 21-29 nucleotides for DXYS15 and 28-33 nucleotides for DXYS17. At reduced stringency, the DXYS15 minisatellite detects other hypervariable sequences located in other parts of the genome and hence represents a new family of minisatellites. In contrast to most other known hypervariable families, the DXYS15 hypervariable sequence displays a very high AT content.

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Year:  1987        PMID： 3595565      PMCID： PMC553490          DOI： 10.1002/j.1460-2075.1987.tb04846.x

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  32 in total

1.  Human-mouse cell hybrid with human multiple Y chromosomes.

Authors:  M Marcus; R Tantravahi; V G Dev; D A Miller; O J Miller
Journal:  Nature       Date:  1976-07-01       Impact factor: 49.962

2.  A hypervariable region 3' to the human apolipoprotein B gene.

Authors:  T J Knott; S C Wallis; R J Pease; L M Powell; J Scott
Journal:  Nucleic Acids Res       Date:  1986-11-25       Impact factor: 16.971

3.  Highly variable regions of DNA flank the human alpha globin genes.

Authors:  D R Higgs; S E Goodbourn; J S Wainscoat; J B Clegg; D J Weatherall
Journal:  Nucleic Acids Res       Date:  1981-09-11       Impact factor: 16.971

4.  The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene.

Authors:  N J Proudfoot; A Gil; T Maniatis
Journal:  Cell       Date:  1982-12       Impact factor: 41.582

5.  Variation in the sequence and modification state of the human insulin gene flanking regions.

Authors:  A Ullrich; T J Dull; A Gray; J A Philips; S Peter
Journal:  Nucleic Acids Res       Date:  1982-04-10       Impact factor: 16.971

6.  Structure of chi hotspots of generalized recombination.

Authors:  G R Smith; S M Kunes; D W Schultz; A Taylor; K L Triman
Journal:  Cell       Date:  1981-05       Impact factor: 41.582

7.  The highly polymorphic region near the human insulin gene is composed of simple tandemly repeating sequences.

Authors:  G I Bell; M J Selby; W J Rutter
Journal:  Nature       Date:  1982-01-07       Impact factor: 49.962

8.  A highly polymorphic locus in human DNA.

Authors:  A R Wyman; R White
Journal:  Proc Natl Acad Sci U S A       Date:  1980-11       Impact factor: 11.205

9.  Genetic homology and crossing over in the X and Y chromosomes of Mammals.

Authors:  P S Burgoyne
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

10.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205
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  22 in total

1.  Characterization of a low copy repetitive element S232 involved in the generation of frequent deletions of the distal short arm of the human X chromosome.

Authors:  X M Li; P H Yen; L J Shapiro
Journal:  Nucleic Acids Res       Date:  1992-03-11       Impact factor: 16.971

2.  A new Rett syndrome family consistent with X-linked inheritance expands the X chromosome exclusion map.

Authors:  N C Schanen; E J Dahle; F Capozzoli; V A Holm; H Y Zoghbi; U Francke
Journal:  Am J Hum Genet       Date:  1997-09       Impact factor: 11.025

3.  Pseudoautosomal repeat displays higher variability in blacks than in Caucasians.

Authors:  G A Rappold; A Henke; M Pohlschmid; T H Huisman
Journal:  Hum Genet       Date:  1992-03       Impact factor: 4.132

4.  Simple repeat sequences on the human Y chromosome are equally polymorphic as their autosomal counterparts.

Authors:  L Roewer; J Arnemann; N K Spurr; K H Grzeschik; J T Epplen
Journal:  Hum Genet       Date:  1992-06       Impact factor: 4.132

Review 5.  Potential genetic functions of tandem repeated DNA sequence blocks in the human genome are based on a highly conserved "chromatin folding code".

Authors:  P Vogt
Journal:  Hum Genet       Date:  1990-03       Impact factor: 4.132

6.  A VNTR immediately adjacent to the human pseudoautosomal telomere.

Authors:  C F Inglehearn; H J Cooke
Journal:  Nucleic Acids Res       Date:  1990-02-11       Impact factor: 16.971

7.  An unusual wheat insertion sequence (WIS1) lies upstream of an alpha-amylase gene in hexaploid wheat, and carries a "minisatellite" array.

Authors:  R A Martienssen; D C Baulcombe
Journal:  Mol Gen Genet       Date:  1989-06

8.  Human satellite-III DNA: an example of a "macrosatellite" polymorphism.

Authors:  C Fowler; R Drinkwater; J Skinner; L Burgoyne
Journal:  Hum Genet       Date:  1988-07       Impact factor: 4.132

9.  Probe walking: development of novel probes for DNA fingerprinting.

Authors:  K Washio; S Misawa; S Ueda
Journal:  Hum Genet       Date:  1989-10       Impact factor: 4.132

10.  Individual specific DNA fingerprints from a hypervariable region probe: alpha-globin 3'HVR.

Authors:  S J Fowler; P Gill; D J Werrett; D R Higgs
Journal:  Hum Genet       Date:  1988-06       Impact factor: 4.132
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