| Literature DB >> 35386240 |
Nevhis Akıntürk1, Mehmet Zileli1, Onur Yaman2.
Abstract
Purpose: Adult spinal deformity incidence increases accordingly as the population ages. Even though surgery is the best option for the treatment, the complications due to surgery are pretty challenging. This study aims to review the complication rates of adult spinal deformity surgery.Entities:
Keywords: Adult spinal deformity; proximal junctional kyphosis; sagittal balance; spinal infection; spine surgery complications
Year: 2022 PMID: 35386240 PMCID: PMC8978850 DOI: 10.4103/jcvjs.jcvjs_159_21
Source DB: PubMed Journal: J Craniovertebr Junction Spine ISSN: 0974-8237
Figure 1Flowchart used for literature search
The articles classified according to level of evidence
| Level of evidence | Number of articles (total 79) |
|---|---|
| 2 | 2 |
| 3 | 58 |
| 4 | 19 |
The articles classified according to methodology
| Study design | Number of articles |
|---|---|
| Prospective, multicenter | 4 |
| Prospective | 4 |
| Retrospective | 48 |
| Retrospective, multicenter | 13 |
| Retrospective review of prospective database | 5 |
| Retrospective review of prospective database, multicenter | 5 |
Summary of the literature review
| Patient data | Values |
|---|---|
| Total number of patients | 26,207 |
| Mean age | 59.8 |
| Number of segments fused | 9.3 |
| Mean operation time (min) | 410.76 |
| Mean blood loss (mL) | 1592.72 |
| Mean follow-up time (months) | 28.85 |
| Total number of complications (%) | 9138/26,207 (34.8) |
| Total number of revision surgery* (%) | 2334/13,067 (17.8) |
*We included the series with 1 year or more follow-up times
Rates of some common complications after adult spinal deformity surgery
| Number of studies examined | Range of complications (%) | Average percentage of complications | |
|---|---|---|---|
| Systemic complications | 37 | 0.1-26 | 4.8 |
| Cardiac | 23 | 0.4-26 | 5.9 |
| Pulmonary | 32 | 0.1-26 | 7.6 |
| DVT | 24 | 0.1-11.5 | 2.9 |
| Renal | 13 | 0.3-7.8 | 2.1 |
| Delirium | 10 | 0.3-7.8 | 2.3 |
| Neurologic complications | 40 | 0.3-35.5 | 10.8 |
| Infection | 33 | 0.3-12.9 | 3.6 |
| Superficial | 23 | 0.3-8.5 | 2.8 |
| Deep | 28 | 0.5-12.9 | 4.1 |
| Implant failure | 59 | 0.7-62.5 | 15.3 |
| Screw loosening | 20 | 0.6-48.5 | 11.1 |
| Rod/screw breakage | 26 | 1.7-31.7 | 13.5 |
| PJK | 53 | 0.7-62.5 | 17.1 |
| DJK | 5 | 0.7-6.8 | 2.6 |
| Revision surgerya | 45 | 10.3-53.7 | 17.8 |
aOnly series with 1 year or more follow-ups were included. DVT: Deep vein thrombosis, PJK: Proximal junctional kyphosis, DJK: Distal junctional kyphosis
Some measures to avoid common complications after adult spinal deformity surgery
| Systemic complications |
| Cardiac |
| Prevent excessive bleeding, apply less invasive surgery |
| Assess cardiac functions meticulously |
| Pulmonary emboli and DVT |
| Use compression stockings |
| Renal |
| Avoid excessive bleeding and fluid replacement |
| Frailty |
| Prehabilitation for frail patients |
| Delirium |
| Treat depression, early mobilization after surgery, psychological support |
| Less corticosteroids, decrease delirium-inducing medications |
| Neurologic complications |
| Intraoperative neuromonitoring |
| Use microscope during decompression |
| Avoid screw malposition by intraoperative fluoroscopy, navigation, EMG monitoring |
| Infection |
| Shorten the operation time, provide less bleeding |
| Weight loss against high body mass index |
| Good regulation of diabetes |
| Repair dural tears, use dural sealants |
| Avoid using steroids |
| Replace blood in case of low hemoglobin level |
| Apply minimally invasive surgeries |
| Preoperative antiseptic dressing |
| Prophylactic antibiotics |
| Intraoperative irrigation of the operation site with saline and antibiotics |
| Implant failure |
| Screw loosening, pseudoarthrosis |
| Manage osteoporosis before surgery |
| Use appropriate amount of bone grafts |
| Achieve a good sagittal balance |
| Rod-screw breakage |
| Use multi-rod constructs |
| Proximal junctional kyphosis |
| Provide sagittal balance |
| Augment cranial level with prophylactic vertebroplasty |
| Use hooks, wires, or polyethylene tethers at the upper end |
| Avoid excessive SVA corrections and excessive lumbar lordosis |
| Avoid soft-tissue and facet joint damage at the UIV |
| Good selection of end vertebra |
| Try less rigid fixations, flexible rods, hybrid constructs |
| Distal junctional kyphosis, caudal ASD |
| Use iliac screws to increase the strength on caudal level |
| Add interbody fusion to L5-S1 level |
DVT: Deep vein thrombosis, SVA: Sagittal vertical axis, ASD: Adjacent segment disease, UIV: Upper instrumented vertebra