Literature DB >> 35186362

A time-based single transmission-line readout with position multiplexing.

Minseok Yi1,2,3, Jae Sung Lee1,2,3,4,5.   

Abstract

We developed a time-based single-transmission-line readout method for time-of-flight positron emission tomography (PET) detectors. The 2D position of a silicon photomultiplier (SiPM) array was encoded in the upper and lower widths of a specially prepared L-shaped tag pulse followed by the original scintillation signal. A PET detector setup was configured using a 4 × 4 array of LSO crystals optically coupled one-to-one to a 4 × 4 SiPM array. Two pulse width modulator circuits were employed per SiPM anode signal channel and a total of 32 width-modulated digital pulses were summed and merged with a delayed common-cathode signal. The final output was analyzed using timestamps crossing two-level threshold voltages. All 16 crystals were clearly separated on a positioning map. The average energy and coincidence time resolutions were 15.0 ± 1.1% and 288.7 ± 29.3 ps after proper correction process, respectively. A 3D position decoding capability was also shown by the remarkable discrimination performance in a phoswich PET detector setup (LSO and LGSO), resulting from well-preserved scintillation signals. The proposed method enables a time-based single-channel readout with 3D gamma ray interaction position decoding capability without compromising on detector performance. This method provides gamma ray energy and arrival time information as well as 2D and depthwise interaction positions of the phoswich detectors through one channel readout. Thus, channels can be reduced by at least 4-5 times compared to typically employed charge-sharing-based position multiplexing method; this significantly reduces the burden of data acquisition on the PET system. © Korean Society of Medical and Biological Engineering 2022.

Entities:  

Keywords:  Depth-of-interaction; Position multiplexing; SiPM (silicon photomultiplier); TOF-PET

Year:  2022        PMID: 35186362      PMCID: PMC8825911          DOI: 10.1007/s13534-022-00215-1

Source DB:  PubMed          Journal:  Biomed Eng Lett        ISSN: 2093-9868


  26 in total

1.  Time-based signal sampling using sawtooth-shaped threshold.

Authors:  Guen Bae Ko; Jae Sung Lee
Journal:  Phys Med Biol       Date:  2019-06-20       Impact factor: 3.609

2.  Highly Integrated FPGA-Only Signal Digitization Method Using Single-Ended Memory Interface Input Receivers for Time-of-Flight PET Detectors.

Authors:  Jun Yeon Won; Jae Sung Lee
Journal:  IEEE Trans Biomed Circuits Syst       Date:  2018-08-15       Impact factor: 3.833

3.  Compact pulse width modulation circuitry for silicon photomultiplier readout.

Authors:  M F Bieniosek; P D Olcott; C S Levin
Journal:  Phys Med Biol       Date:  2013-07-08       Impact factor: 3.609

4.  Development of small-animal PET prototype using silicon photomultiplier (SiPM): initial results of phantom and animal imaging studies.

Authors:  Sun Il Kwon; Jae Sung Lee; Hyun Suk Yoon; Mikiko Ito; Guen Bae Ko; Jae Yeon Choi; Sung-Hyuk Lee; In Chan Song; Jae Min Jeong; Dong Soo Lee; Seong Jong Hong
Journal:  J Nucl Med       Date:  2011-03-18       Impact factor: 10.057

Review 5.  Application of silicon photomultipliers to positron emission tomography.

Authors:  Emilie Roncali; Simon R Cherry
Journal:  Ann Biomed Eng       Date:  2011-02-15       Impact factor: 3.934

6.  Comparator-less PET data acquisition system using single-ended memory interface input receivers of FPGA.

Authors:  Jun Yeon Won; Guen Bae Ko; Kyeong Yun Kim; Haewook Park; Seungeun Lee; Jeong-Whan Son; Jae Sung Lee
Journal:  Phys Med Biol       Date:  2020-04-03       Impact factor: 3.609

7.  A CMOS ASIC Design for SiPM Arrays.

Authors:  Samrat Dey; Lushon Banks; Shaw-Pin Chen; Wenbin Xu; Thomas K Lewellen; Robert S Miyaoka; Jacques C Rudell
Journal:  IEEE Trans Nucl Sci       Date:  2011-12       Impact factor: 1.679

8.  Continuous depth-of-interaction encoding using phosphor-coated scintillators.

Authors:  Huini Du; Yongfeng Yang; Jarek Glodo; Yibao Wu; Kanai Shah; Simon R Cherry
Journal:  Phys Med Biol       Date:  2009-03-03       Impact factor: 3.609

9.  Improved single photon time resolution for analog SiPMs with front end readout that reduces influence of electronic noise.

Authors:  Joshua W Cates; Stefan Gundacker; Etiennette Auffray; Paul Lecoq; Craig S Levin
Journal:  Phys Med Biol       Date:  2018-09-19       Impact factor: 3.609

10.  A digital phoswich detector using time-over-threshold for depth of interaction in PET.

Authors:  David L Prout; Zheng Gu; Max Shustef; Arion F Chatziioannou
Journal:  Phys Med Biol       Date:  2020-12-15       Impact factor: 3.609

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  1 in total

Review 1.  Silicon photomultiplier signal readout and multiplexing techniques for positron emission tomography: a review.

Authors:  Haewook Park; Minseok Yi; Jae Sung Lee
Journal:  Biomed Eng Lett       Date:  2022-07-16
  1 in total

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