Audit of outcomes following attendance at the City West drive-through IOP glaucoma clinic during the COVID-19 pandemic.

BACKGROUND: Glaucoma is the leading cause of irreversible blindness globally. During the COVID-19 pandemic, an enforced reduction in capacity resulted in the deferral of routine outpatient appointments for glaucoma patients. AIM: This study analyses patient outcomes following the establishment of a drive-through intra-ocular pressure (IOP) clinic during the COVID-19 pandemic to alleviate increased pressure on the tertiary glaucoma services at Royal Victoria Eye and Ear Hospital (RVEEH) and Mater Misericordiae University Hospital (MMUH) between August 2020 and June 2021.
METHODS: A 1-lane driveway system was established in a marquee on the grounds of City West hotel. IOPs were measured in patients' cars using a hand held iCare100 tonometer. Results were reviewed by a consultant ophthalmologist. At hospital follow-up clinic visits, IOP was measured using the Goldmann applanation tonometer (GAT).
RESULTS: Three hundred one patients of a total of 672 who attended the drive-through clinic have subsequently attended a designated hospital follow-up appointment. In this cohort, the mean drive-through iCare IOP of 19.4 mmHg ± 6.0 was significantly higher (< 0.005) than the mean GAT IOP at the pre-drive through clinic visit (16.3 mmHg ± 3.7) and the post drive-through hospital follow-up visit (17.2 mmHg ± 4.1). Two hundred twenty-six (75%) patients did not need any treatment change, 53 (18%) required eye drop medication changes, 10 (3%) underwent a laser procedure, 4(1%) required surgical intervention, and 8 (3%) were discharged. When patient outcomes were analysed according to IOP grade assigned at the drive-through clinic, those with an iCare IOP < 21 were significantly less likely to require a treatment change. The cohort with iCare IOP ≥ 30 were significantly more likely to have a laser or surgical intervention.
CONCLUSION: The implementation of a drive-through IOP clinic was a safe and effective way to monitor glaucoma patients during COVID-19, and identify those at high risk of poor IOP control or requiring a change in treatment.

Introduction

Glaucoma is the second leading cause of blindness in Ireland after age-related macular degeneration (ARMD), accounting for 12% of registrations with the National Council for the Blind in Ireland (NCBI) in 2003 [1]. In 2020, glaucoma was reported as the leading cause of preventable blindness in the United Kingdom (UK), accounting for almost one-third of new vision impairment certifications [2]. This was due to a relative decrease in registrations caused by ARMD and diabetic eye disease.

In 2017, the British Ophthalmological Surveillance unit found that up to 22 people per month suffered permanent and severe vision loss as a consequence of delayed follow-up due to insufficient capacity within hospital eye services [3]. The most common diagnosis in this group was glaucoma [4]. This finding led to recommendations specific to the subspecialty of glaucoma for clinical pathway redesign. National guidance has been issued regarding the use of ‘virtual’ glaucoma clinics to increase capacity [5]. Virtual clinics have been implemented in centres across the UK [6-9]. Fifty percent of respondents to a UK national survey of clinical leads carried out in 2016 were already utilising glaucoma virtual clinics, with a further 21.4% planning to establish ones. The majority of those running virtual clinics used this model of care for ‘lower risk’ patients such as ocular hypertensives and glaucoma suspects. [9] Remote decision-making using data collected from glaucoma patients has been shown to be both safe and efficient [8].

In Ireland, the National Care Plan for Ophthalmology aims for 80% of glaucoma patients to be managed in the primary care eye setting, but states that glaucoma as a disease lends itself to tele-medicine, virtual clinics and obtaining an expert opinion from a distant location is generally possible [10]. To date, one centre in Ireland has implemented a virtual glaucoma service. With the establishment of the first Community Eyecare centres in 2020, led by consultant medical ophthalmologists, plans to extend such clinics into the community are at an advanced stage and links to the tertiary glaucoma services and the expertise of a glaucoma consultant will be available.

The provision of safe and effective glaucoma care even prior to the COVID-19 pandemic was challenging. Increased virtual services were becoming the recommended method of monitoring. During the pandemic, an enforced reduction in capacity resulted in the deferral of routine outpatient appointments. Our literature review revealed strategies adopted to minimise the impact of delayed care worldwide. Some form of telehealth/telemedicine has been adopted in ophthalmological centres in the USA, UK, India, Hong Kong, and Singapore in response to the pandemic [11-15] subspecialties of medical retina, paediatric ophthalmology, neuro-ophthalmology, and glaucoma [14, 16–18]. Specific to glaucoma care, Bommakanti et al. developed a flexible and scalable scoring algorithm for patients with glaucoma that considers glaucoma severity and progression risk versus the presence of high-risk features for morbidity from COVID-19, using information from a large data repository. This facilitated the triage, postponing and rescheduling of ophthalmic appointments [19].

Drive-through IOP clinics were utilised for glaucoma patients in two centres in the USA and in Belfast during the pandemic [20, 21]. Shah et al. compared subjects that received E-health visits versus subjects that received E-health visits with a drive-through IOP check. The rate of intervention was significantly higher in the group that received an IOP check [21].

Our aims with this study are to describe the establishment of a drive-through satellite IOP clinic in Dublin, Ireland, during the COVID-19 pandemic, and to determine patient outcomes in terms of IOP measurement and change in treatment following review back in the hospital setting. This was done to relieve pressure on the tertiary glaucoma services at the Royal Victoria Eye and Ear Hospital (RVEEH) and Mater Misericordiae University Hospital (MMUH).

Methods

This retrospective audit examined all MMUH and RVEEH glaucoma patients that attended the City West IOP drive-through clinic initiative between August 2020 and June 2021 who were subsequently followed up in a face-to-face hospital outpatient clinic setting.

Patient selection

Medical records of MMUH (PatientCentre) and RVEEH (Electronic Patient Record system Medisight or Docman) patients who normally attended outpatient glaucoma clinics in both tertiary referral centres, and whose appointments were either cancelled or delayed due to COVID-19 were reviewed by an ophthalmologist. Information pertaining to each patients diagnosis, last clinic IOP, and current treatment regimen were recorded. All patients deemed eligible then received a phone invitation to attend City West drive-through IOP clinic, and those that agreed to attend were subsequently sent an appointment letter and information leaflet by post, which contained written instructions detailing what the drive-through clinic process entailed.

Patients who attended CW drive through IOP clinic and who were included in this audit had a range of diagnoses, including ocular hypertension (OHT), primary open angle glaucoma (POAG), normal tension glaucoma (NTG), angle closure glaucoma (ACG), secondary glaucoma, and glaucoma suspects.

City West IOP clinic process

A 1-lane driveway system was established in a marquee on the grounds of City West hotel in Dublin. Patients, who were given 10-min appointment slots, drove into the marquee and lined up in their cars (Fig. 1). An ophthalmic nurse confirmed the patients identity, and conducted a COVID-19 screening questionnaire. All patients were required to wear face masks, and staff wore protective personal equipment (PPE). IOPs were measured in patients’ cars using a hand held iCare100 tonometer (iCare IC 100), which records the average of six IOP readings for each eye.

Fig. 1

City West drive-through intra-ocular pressure (IOP) clinic

Results were input onto Medisight (RVEEH) or PatientCentre (MMUH), where they could then be reviewed by a consultant ophthalmologist, and a decision about when to organise an outpatient follow-up appointment for each patient was made. At MMUH, subjects were all seen back in a face-to-face doctor-led clinic. At RVEEH, subjects were distributed between face-to-face doctor-led clinics, face-to-face nurse-led clinics, and the virtual glaucoma assessment clinic (GAC) which is in operation since 2019. At the GAC, a nurse collects data including GAT, 3D disc photographs with a Kowa nonmydriatic WX 3D camera (Kowa, Tokyo, Japan), and Humphrey visual field SITA 24–2 (Humphrey Instruments, Dublin, CA, USA). These results are later reviewed by an ophthalmologist.

Patient follow-up

Three hundred one subjects in total (179 from RVEEH and 122 from MMUH) were followed up by an ophthalmologist in a virtual (following nurse review) or face-to-face clinic after their City West IOP check between September 2020 and June 2021. These patients were graded according to their City West IOP, as described in Table 1.

Table 1

Grading system as per City West IOP. Patients were graded per their IOP in one or both eyes

Grade	City West IOP (in one or both eyes)
1	< 21
2	21–25
3	26–29
4	≥ 30

At follow-up face-to-face clinic visits in RVEEH and MMUH, IOP was measured using the gold standard Goldmann applanation tonometer (GAT), and patient outcomes were recorded and grouped accordingly — no change in treatment, change in medication, laser treatment, surgical intervention or discharge.

Early review/follow-up criteria

Criteria for early review/follow-up included IOP > / + 4 mmHg higher versus last clinic GAT IOP or IOP > 21 plus self-reporting of symptoms of ocular discomfort, poor adherence to drops or symptoms of drop intolerance.

Statistical analyses

Comparison of the IOP data between the two sites was carried out with an independent two-sample T test. Comparison of the drive-through IOP with the pre drive-through and post drive-through IOP was done with a one-way ANOVA test, with Bonferroni-corrected post-test paired t-test. Comparison of the drive-through IOP in the subgroups of subjects with ocular hypertension, glaucoma (incorporating the subgroups of POAG, NTG, ACG, and secondary glaucoma) and glaucoma suspects was carried out with a one-way ANOVA test, with Bonferroni-corrected post-test paired t-test. Patient outcomes were analysed across the same three diagnostic groups with a chi-squared test for independence, with Bonferroni adjustment. Patient outcomes between sites were also analysed in this way, as were patient outcomes according to IOP grade. All statistical and graphical analyses were performed using Microsoft® Excel for Mac Version 16.16.27 and GraphPad Prism version 9.2.0.

Results

Between September 2020 and June 2021, 672 subjects attended the drive-through clinic: 138 from MMUH and 534 from RVEEH. At the time the audit was conducted (June 2021), 301 of these (122 from MMUH and 179 from RVEEH) have subsequently attended their designated follow-up appointments. Diagnoses of all subjects from both sites are as depicted in Table 2.

Table 2

Diagnosis of all subjects overall, then subdivided by site

	Overall		RVEEH		MMUH
	n = 301	%	n = 179	%	n = 122	%
OHT	87	29%	52	29%	35	29%
NTG	13	4%	2	1%	11	9%
POAG	65	22%	31	17%	34	28%
ACG	25	8%	13	7%	12	10%
Glaucoma suspects	76	25%	64	36%	12	10%
Secondary glaucoma	35	12%	17	9%	18	15%

RVEEH Royal Victoria Eye and Ear Hospital; MMUH Mater Misericordiae University Hospital; OHT ocular hypertension; NTG normal tension glaucoma; POAG primary open angle glaucoma; ACG angle closure glaucoma

Mean drive-through iCare IOP overall was 19.4 mmHg ± 6.0. Mean drive-through IOP in the MMUH group was 19.1 mmHg ± 6.2 compared to 19.6 mmHg ± 6.0 in the RVEEH patient cohort. There was no significant difference found between groups (p = 0.5). Mean drive-through IOP in the OHT subgroup was significantly higher at 21.7 mmHg ± 6.0 than that of the glaucoma and glaucoma suspects groups (18.7 mmHg ± 6.2 and 18.1 ± 5.1 respectively) (p = 0.02) (Fig. 2).

Fig. 2

Drive-through IOP (with iCare) compared between diagnostic subgroups. OHT, ocular hypertension; Suspect, glaucoma suspect; Glaucoma, includes POAG, NTG, ACG and secondary glaucoma subgroups

Mean drive-through iCare IOP in the group overall (19.4 mmHg ± 6.0) was significantly higher than both the mean GAT IOP at the pre-drive through OPD visit (16.3 mmHg ± 3.7) and the mean GAT IOP at the post drive-through follow-up visit (17.2 mmHg ± 4.1) (p = 0.01) (Fig. 3).

Fig. 3

Drive-through IOP (with iCare) compared to the pre drive-through GAT IOP and post drive-through GAT IOP recorded for each subject

The change in treatment outcomes of patients is shown in Table 3.

Table 3

Patient outcomes for all subjects, then subdivided by site

	Overall		RVEEH		MMUH
	n = 301	%	n = 179	%	n = 122	%
No change	226	75	131	73	95	78
Med	53	18	32	18	21	17
Laser	10	3	6	3	4	3
Surgery	4	1	3	2	1	1
Discharged	8	3	7	4	1	1

RVEEH Royal Victoria Eye and Ear Hospital; MMUH Mater Misericordiae University Hospital

The difference in frequency of outcomes between the two sites was found to be non-significant. Where a laser intervention was required in the group overall (n = 10), these included selective laser trabeculoplasty (n = 5), peripheral iridotomy (n = 3), and cyclodiode laser (n = 2). Where a surgical intervention was required (n = 4), these included trabeculectomy (n = 1), cataract surgery (n = 2), and cataract surgery combined with cyclodiode laser (n = 1).

When patient outcomes were analysed according to diagnosis (Table 4), the patients that were glaucoma suspects were significantly more likely to be discharged from the glaucoma service than subjects from the other two groups. There was otherwise no significant difference in frequency of outcomes.

Table 4

Patient outcomes by diagnosis

	OHT		Glaucoma suspects		Glaucoma
	n = 87	%	n = 76	%	n = 138	%
No change	68	78	58	76	100	72
Med	16	18	10	13	27	20
Laser	1	1	2	3	7	5
Surgery	1	1	0	0	3	2
Discharged at follow-up	1	1	6	8	1	1

OHT ocular hypertension. Glaucoma includes subgroups of POAG, NTG, ACG, and secondary glaucoma

In this cohort of 301 patients, 162 patients had iCare IOP < 21 mmHg, 69 patients had iCare IOP between 21 and 25 mmHg, 34 between 26 and 30 mmHg, and 37 patients had iCare readings ≥ 30 mmHg. All notes of patients with iCare readings > 21 mmHg were reviewed shortly after CW by a clinician to determine how urgently they needed hospital review. When patient outcomes were analysed according to iCare IOP measurement assigned at the drive-through clinic (Table 5), those in the group with IOP < 21 were significantly more likely to have no change to treatment. Those in the group with IOP ≥ 30 were significantly more likely to have change in treatment, as well as being more likely to have a laser or surgical intervention. There was otherwise no significant difference in frequency of outcomes across the IOP subgroups.

Table 5

Patient outcomes by IOP grades < 21 mmHg, 21–25 mmHg, 26–29 mmHg, and ≥ 30 mmHg

	IOP < 21		IOP 21–25		IOP 26–29		IOP ≥ 30
	n = 162	%	n = 69	%	n = 34	%	n = 37	%
No change	135	83%	50	72%	23	68%	18	49%
Med	21	13%	17	25%	6	18%	10	27%
Laser	1	1%	0	0%	4	12%	5	14%
Surgery	0	0%	0	0%	0	0%	4	11%
Discharged	5	3%	2	3%	1	3%	0	0%

Discussion

The COVID-19 pandemic has shaped a new landscape by which ophthalmic care in general, and glaucoma care in particular, will be delivered in the future. In March 2020, all elective and non-urgent ophthalmic care was cancelled in Ireland whilst the Health Service Executive (HSE) focused on safeguarding intensive care unit capacities and halting the inexorable spread of COVID-19 in the community and in hospitals nationwide.

As elective and non-urgent hospital care was cancelled in order to prioritise and provide appropriate medical care for those sickest, almost overnight ophthalmologists found themselves in the difficult position of being unable to see and examine those patients deemed to be non-urgent in-person. Initiatives such as telemedicine, phone consultations, and virtual clinics rose to prominence as new, effective methods by which to provide efficient, effective ophthalmic care [22, 23]. However, telemedicine has clear drawbacks in ophthalmic care, and in particular in glaucoma, where measurements and values obtained at real patient visits are a critical part of the treatment decision-making process. Agreed Guidelines were drawn up by RVEEH and MMUH under the auspices of the Ireland East Hospital Group to ensure that those in urgent need of glaucoma-related care would be seen, but the majority of glaucoma patients did not fall into this category. Following a 2–3 months closure to direct consultations, the ability to return to normal capacity was greatly impaired by new infection control guidelines, the continuing high risk of COVID transmission and the need for social distancing and adequate ventilation in busy and previously overcrowded environments, as well as reluctance by patients to enter the hospital environment due to perceived high risk of transmission amongst healthcare workers.

The Royal College of Ophthalmologists (RCOphth) published a set of guidelines pertaining to the delivery of glaucoma care during COVID-19, outlining care pathways for glaucoma patients during the pandemic and providing advice to ophthalmologists regarding the stratification of patients who need urgent care, simultaneously balancing the risk of COVID-19 and its disease sequelae, with the consequences of permanent vision loss due to treatment delays [22, 24].

One large UK eyecare centre increased the provision of technician-led remote monitoring clinics to facilitate a major shift to consultant-led virtual review. This centre also recommended that shared care collaborations between commissioners, primary care settings, and high street optometry providers must be accelerated in order to facilitate the capture of patient data closer to home, away from the hospital environment, but with the capability for all necessary data to be available for consultant-led decision making [14].

Husain et al. whilst giving perspectives on management of glaucoma patients during the pandemic in Singapore describe the increased utilisation of video consultations, both with and without the collection of IOP, visual field and posterior segment photography data in satellite units.[25] During their pilot trials of this model of care, a satisfaction survey on glaucoma patients/glaucoma suspects showed that 94.8% agreed that the care they received was satisfactory.

An enforced reduction in capacity during COVID-19 resulted in the deferral of routine outpatient appointments for glaucoma patients. It was determined that a drive-through IOP clinic using the iCare tonometer would address many of the concerns above. It was decided that a short questionnaire (Appendix 1), in conjunction with an iCare IOP measurement, would provide sufficient information to identify patients at high risk of glaucoma progression, to enable their swift return to the main glaucoma clinic for assessment regarding medication changes or possible intervention. IOP is the main modifiable risk factor for disease progression, and issues relating to drop use, compliance, toxicity, and dryness were identified by the questionnaire. The clinic was located in an off-site location from the main hospitals, and therefore negated problems such as car-parking, and also provided a more attractive option for patients with concerns about entering a hospital environment during COVID-19.

iCare tonometry

Accurate IOP measurement is an integral component of every routine ophthalmic examination. Glaucoma as a subspecialty, in particular, relies heavily on accurate IOP measurement as a critical parameter in the formulation of management plans and treatment regimens for patients [26]. Whilst GAT remains the gold standard and most reliable IOP measurement used in clinical practice, [27] in recent years several alternative IOP measurement instruments and techniques have been developed and introduced into ophthalmic care in an outpatient setting [28]. Amongst these is the iCare rebound tonometer, a small hand-held machine with a single-use magnetised probe which records the average reading of six IOP measurements per eye. When compared to GAT, iCare tonometry is a quicker, more comfortable IOP measurement for patients, it is anaesthetic and eye drop free, and it requires very little staff training [29, 30]

iCare versus GAT

Several studies have compared the efficacy of the iCare tonometer to the GAT method, with largely reassuring results over a low to moderate IOP range [31]. Chen et al. analysed iCare and GAT IOP measurements in 200 subjects and found that there was no statistical difference between the groups, with > 90% IOP measurements within ± 3 mmHg in low and normal IOP range, and 80% were within ± 3 mmHg in elevated IOP cohort [32]. Similarly, Scuduri et al. compared iCare and GAT IOP measurements in 97 subjects, and their results showed that the iCare method was agreeable and highly consistent with GAT. [33] iCare tonometry has also been shown to be a reliable IOP measuring tool in inexperienced hands. Abraham et al. showed that non-ophthalmologists could accurately measure IOP using iCare tonometry, and therefore deduced it is an accurate and acceptable IOP measurement method, especially in situations where GAT is unavailable, or when patients are not suitable for IOP measurements by GAT [33, 34].

However, some studies have found that iCare accuracy is inconsistent when compared to GAT. Nakamura et al. found that although iCare was agreeable with GAT, the device tended to significantly overestimate IOP more than GAT as patients’ central corneal thickness (CCT) was thicker [35]. Kim et al. analysed iCare PRO versus GAT in 86 glaucoma patients (172 eyes) and found that iCare was a reliable substitute for GAT, although it somewhat overestimated IOP reading especially at lower IOP values when compared to GAT. Contrary to Nakura et al. iCare PRO was unaffected by CCT in this study. Tamaçelik et al. found that iCare was highly agreeable with GAT especially in normal IOP range (10–22 mmHg); however, they found significant discrepancies between the two methods in IOP ranges < 9 and > 22. Similar to Nakura et al. they concluded that CCT had no effect on iCare measurements in this study [36].

In our study, we found that the mean iCare IOP in the overall cohort was significantly higher than both mean GAT IOP at the pre-drive through clinic and outpatient follow-up clinic. This may suggest that in our patient cohort, iCare overestimated the IOP when compared to GAT; however, it is difficult to definitively conclude this. Two methods of IOP measurement were performed at different timepoints (pre-drive through, drive through, and post-drive through follow-up), and at various times throughout the day, thereby making a conclusion difficult to generate. Furthermore, CCT measurement was not collected on all patients; therefore, we cannot draw a conclusion as to whether IOP as measured by iCare was influenced by CCT in our patient group.

Patient diagnoses

Overall, the most common diagnoses between the two groups were OHT, followed by glaucoma suspects and POAG. OHT was the most common diagnosis amongst the MMUH patient cohort (29% versus 29% in RVEEH), whereas glaucoma suspects was the number one diagnosis in the RVEEH group (36%). There is a significantly higher percentage of glaucoma suspects in the RVEEH patient cohort when compared to MMUH (10%), possibly due to the higher number of glaucoma suspect patients in virtual clinics. Furthermore, a much higher percentage of POAG patients were observed in the MMUH patient cohort when compared to RVEEH (28% versus 17%). A significant proportion of the patients came from a pre-existing stable glaucoma nurse-led clinic as all patients booked to attend that clinic were invited to attend the drive-through clinic option.

Patient outcomes

Overall, 45% of all patients who attended the drive-through clinic have attended subsequent follow-up outpatient appointments. Seventy-five percent of these patients (RVEEH: 73%, MMUH 78%) needed no treatment change after their follow-up appointments, and could continue with their current treatment regimen. Eighteen percent (RVEEH: 18%, MMUH: 17) required a change in medication that was due to elevated IOP (Table 4). Overall, the OHT cohort were the most likely group of patients not to need any changes in medication (78%) when compared to glaucoma suspects (76%) and patients diagnosed with glaucoma (72%). As a sub-group, patients with glaucoma were most likely to have their medication changed (20%)versus OHT and glaucoma suspects (18% and 13%, respectively). This is not surprising given that these patients have existing visual field loss and are more at risk of needing further intervention. As expected, patients with IOP < 21 were most likely to need no change in treatment (83%)(Table 5) and subjects with IOP ≥ 30 were most likely to need a change in medication (27%), undergo laser (14%) or surgical intervention (11%). The percentage of NTG sent to the CW clinic was low. NTG is a condition in which treatment change is more likely to be made based on changes in the visual field, optic nerve examination, medical history, or other ancillary tests as opposed to the IOP alone. Fluctuations in the IOP are arguably of less importance in these patients unless additional information is available to correlate with the IOP.

It is not yet known the extent that the impact of the reduction and disruption to the provision of ophthalmic care during COVID-19 will have on glaucoma patients in the future, though it is reasonable to assume that there will unfortunately be considerable adverse downstream consequences for patients. Fortner and Lindsey reported increased rates of glaucoma progression in a group of patients who experienced delayed ophthalmic care during the pandemic at a US centre (37.5% during the pandemic versus 17.0% pre pandemic).[37] Pujari et al. assessed the impact of COVID-19 on glaucoma patients using the patient-reported outcome and experience measure (POEM). They found that patients were more uncertain regarding how their glaucoma was being managed, and more anxious about disease progression [38]. These studies highlight the fundamental importance of the development of innovative measures such as drive-through IOP clinics in order to maintain effective delivery of glaucoma care, but also to lessen patient anxiety and worry surrounding their treatment and prognosis, especially during the uncertainty of COVID-19.

Study limitations

There are a number of limitations of this retrospective audit. Firstly, not all patients had Humphrey visual fields (HVF) performed at follow-up OPD visits; thus, it is difficult to ascertain the rates of glaucoma progression amongst this cohort of patients. Over the next 12 months, we envisage this will be done for the full cohort of 672 patients who attended CW drive-through clinic, and the outcomes reported. Secondly, patients with a wide range of risk factors and varying degrees of disease severity were selected from both centres. In particular, RVEEH patients were selected from either a nurse-led, virtual clinic or from main OPD glaucoma clinic, whereas all of the MMUH patients were selected from main OPD glaucoma clinics. In general, patients attending the virtual/nurse-led clinics are stable patients, and therefore there may be a higher incidence of treatment change or interventions in the main glaucoma clinic cohort.

Conclusion

In summary, the implementation of a drive-through satellite IOP clinic in Dublin was a safe and effective way of stratifying and identifying high-risk glaucoma patients during the COVD-19 pandemic in Ireland whilst simultaneously maintaining patient and staff safety. As health systems and economies across the globe recover from COVID-19, and as we emerge into an uncertain post-COVID future, ophthalmology must seek more efficient methods of stratifying risk and reducing number of in-person visits for patients in the low-risk category to allow us to detect those at highest risk of progression. It is hoped that in this way we can reduce the number progressing due to delayed care. The development of virtual clinics such as this one described, alongside advances in technology, imaging technologies, and artificial intelligence (AI), renders ophthalmology as one of the specialities most poised to pave the way for the transformation of healthcare and to ensure the delivery of high-quality ophthalmic patient care.