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Literature DB >> 33880795

Neutrophils: mediating TelOxidation and senescence.

Maria Sol Jacome Burbano¹, Julien Cherfils-Vicini¹, Eric Gilson^1,2.

Abstract

Cellular senescence is considered to be a major driver of aging, yet the mechanisms explaining the accumulation of senescent cells during life time remain unclear. In this issue, Lagnado et al (2021) show that neutrophils can trigger the senescence of neighboring cells by transmitting reactive oxygen species (ROS), which they normally produce to fight pathogens. The main genomic targets of the neutrophil-mediated ROS damage are telomeres, supporting an intimate interplay between telomere homeostasis and oxidative stress in senescence and consequently aging.

Entities: Chemical

Mesh：

Substances：
Reactive Oxygen Species

Year: 2021 PMID： 33880795 PMCID： PMC8090830 DOI： 10.15252/embj.2021108164

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 11.598

13 in total

Review 1. Review article: ageing and the neutrophil: no appetite for killing?

Authors: S Butcher; H Chahel; J M Lord
Journal: Immunology Date: 2000-08 Impact factor: 7.397

2. Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress.

Authors: Shaheda Ahmed; João F Passos; Matthew J Birket; Tina Beckmann; Sebastian Brings; Heiko Peters; Mark A Birch-Machin; Thomas von Zglinicki; Gabriele Saretzki
Journal: J Cell Sci Date: 2008-03-11 Impact factor: 5.285

3. Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice.

Authors: Jean Albrengues; Mario A Shields; David Ng; Chun Gwon Park; Alexandra Ambrico; Morgan E Poindexter; Priya Upadhyay; Dale L Uyeminami; Arnaud Pommier; Victoria Küttner; Emilis Bružas; Laura Maiorino; Carmelita Bautista; Ellese M Carmona; Phyllis A Gimotty; Douglas T Fearon; Kenneth Chang; Scott K Lyons; Kent E Pinkerton; Lloyd C Trotman; Michael S Goldberg; Johannes T-H Yeh; Mikala Egeblad
Journal: Science Date: 2018-09-28 Impact factor: 47.728

Review 4. Cellular Senescence: Defining a Path Forward.

Authors: Vassilis Gorgoulis; Peter D Adams; Andrea Alimonti; Dorothy C Bennett; Oliver Bischof; Cleo Bishop; Judith Campisi; Manuel Collado; Konstantinos Evangelou; Gerardo Ferbeyre; Jesús Gil; Eiji Hara; Valery Krizhanovsky; Diana Jurk; Andrea B Maier; Masashi Narita; Laura Niedernhofer; João F Passos; Paul D Robbins; Clemens A Schmitt; John Sedivy; Konstantinos Vougas; Thomas von Zglinicki; Daohong Zhou; Manuel Serrano; Marco Demaria
Journal: Cell Date: 2019-10-31 Impact factor: 41.582

5. Telomere dysfunction induces metabolic and mitochondrial compromise.

Authors: Ergün Sahin; Simona Colla; Marc Liesa; Javid Moslehi; Florian L Müller; Mira Guo; Marcus Cooper; Darrell Kotton; Attila J Fabian; Carl Walkey; Richard S Maser; Giovanni Tonon; Friedrich Foerster; Robert Xiong; Y Alan Wang; Sachet A Shukla; Mariela Jaskelioff; Eric S Martin; Timothy P Heffernan; Alexei Protopopov; Elena Ivanova; John E Mahoney; Maria Kost-Alimova; Samuel R Perry; Roderick Bronson; Ronglih Liao; Richard Mulligan; Orian S Shirihai; Lynda Chin; Ronald A DePinho
Journal: Nature Date: 2011-02-09 Impact factor: 49.962

Review 6. The impact of oxidative DNA damage and stress on telomere homeostasis.

Authors: Ryan P Barnes; Elise Fouquerel; Patricia L Opresko
Journal: Mech Ageing Dev Date: 2018-03-28 Impact factor: 5.432

7. MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress.

Authors: Gabriele Saretzki; Michael P Murphy; Thomas von Zglinicki
Journal: Aging Cell Date: 2003-04 Impact factor: 9.304

8. Neutrophils: mediating TelOxidation and senescence.

Authors: Maria Sol Jacome Burbano; Julien Cherfils-Vicini; Eric Gilson
Journal: EMBO J Date: 2021-04-20 Impact factor: 11.598

9. Mitochondrial function in skeletal myofibers is controlled by a TRF2-SIRT3 axis over lifetime.

Authors: Jérôme D Robin; Maria-Sol Jacome Burbano; Han Peng; Olivier Croce; Jean Luc Thomas; Camille Laberthonniere; Valerie Renault; Liudmyla Lototska; Mélanie Pousse; Florent Tessier; Serge Bauwens; Waiian Leong; Sabrina Sacconi; Laurent Schaeffer; Frédérique Magdinier; Jing Ye; Eric Gilson
Journal: Aging Cell Date: 2020-01-28 Impact factor: 9.304

10. Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner.

Authors: Anthony Lagnado; Jack Leslie; Marie-Helene Ruchaud-Sparagano; Stella Victorelli; Petra Hirsova; Mikolaj Ogrodnik; Amy L Collins; Maria Grazia Vizioli; Leena Habiballa; Gabriele Saretzki; Shane A Evans; Hanna Salmonowicz; Adam Hruby; Daniel Geh; Kevin D Pavelko; David Dolan; Helen L Reeves; Sushma Grellscheid; Colin H Wilson; Sanjay Pandanaboyana; Madison Doolittle; Thomas von Zglinicki; Fiona Oakley; Suchira Gallage; Caroline L Wilson; Jodie Birch; Bernadette Carroll; James Chapman; Mathias Heikenwalder; Nicola Neretti; Sundeep Khosla; Claudio Akio Masuda; Tamar Tchkonia; James L Kirkland; Diana Jurk; Derek A Mann; João F Passos
Journal: EMBO J Date: 2021-03-25 Impact factor: 11.598

4 in total