Literature DB >> 35165420

Telomere dysfunction in ageing and age-related diseases.

Francesca Rossiello1, Diana Jurk2,3, João F Passos4,5, Fabrizio d'Adda di Fagagna6,7.   

Abstract

Ageing organisms accumulate senescent cells that are thought to contribute to body dysfunction. Telomere shortening and damage are recognized causes of cellular senescence and ageing. Several human conditions associated with normal ageing are precipitated by accelerated telomere dysfunction. Here, we systematize a large body of evidence and propose a coherent perspective to recognize the broad contribution of telomeric dysfunction to human pathologies.
© 2022. Springer Nature Limited.

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Year:  2022        PMID： 35165420      PMCID： PMC8985209          DOI： 10.1038/s41556-022-00842-x

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.213


  189 in total

1.  A DNA damage checkpoint response in telomere-initiated senescence.

Authors:  Fabrizio d'Adda di Fagagna; Philip M Reaper; Lorena Clay-Farrace; Heike Fiegler; Philippa Carr; Thomas Von Zglinicki; Gabriele Saretzki; Nigel P Carter; Stephen P Jackson
Journal:  Nature       Date:  2003-11-05       Impact factor: 49.962

2.  p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2.

Authors:  J Karlseder; D Broccoli; Y Dai; S Hardy; T de Lange
Journal:  Science       Date:  1999-02-26       Impact factor: 47.728

3.  Autophagic cell death restricts chromosomal instability during replicative crisis.

Authors:  Joe Nassour; Robert Radford; Adriana Correia; Javier Miralles Fusté; Brigitte Schoell; Anna Jauch; Reuben J Shaw; Jan Karlseder
Journal:  Nature       Date:  2019-01-23       Impact factor: 49.962

Review 4.  Senescence in Health and Disease.

Authors:  Shenghui He; Norman E Sharpless
Journal:  Cell       Date:  2017-06-01       Impact factor: 41.582

5.  How telomeres solve the end-protection problem.

Authors:  Titia de Lange
Journal:  Science       Date:  2009-11-13       Impact factor: 47.728

6.  Telomeres shorten during ageing of human fibroblasts.

Authors:  C B Harley; A B Futcher; C W Greider
Journal:  Nature       Date:  1990-05-31       Impact factor: 49.962

7.  Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a).

Authors:  Utz Herbig; Wendy A Jobling; Benjamin P C Chen; David J Chen; John M Sedivy
Journal:  Mol Cell       Date:  2004-05-21       Impact factor: 17.970

Review 8.  Living on a break: cellular senescence as a DNA-damage response.

Authors:  Fabrizio d'Adda di Fagagna
Journal:  Nat Rev Cancer       Date:  2008-07       Impact factor: 60.716

Review 9.  A three-state model of telomere control over human proliferative boundaries.

Authors:  Anthony J Cesare; Jan Karlseder
Journal:  Curr Opin Cell Biol       Date:  2012-09-02       Impact factor: 8.382

Review 10.  The central role of DNA damage in the ageing process.

Authors:  Björn Schumacher; Joris Pothof; Jan Vijg; Jan H J Hoeijmakers
Journal:  Nature       Date:  2021-04-28       Impact factor: 49.962
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  10 in total

Review 1.  Genetics of human telomere biology disorders.

Authors:  Patrick Revy; Caroline Kannengiesser; Alison A Bertuch
Journal:  Nat Rev Genet       Date:  2022-09-23       Impact factor: 59.581

2.  Physical Activity Rewires the Human Brain against Neurodegeneration.

Authors:  Jose A Santiago; James P Quinn; Judith A Potashkin
Journal:  Int J Mol Sci       Date:  2022-06-02       Impact factor: 6.208

Review 3.  Clonal Hematopoiesis and Myeloid Neoplasms in the Context of Telomere Biology Disorders.

Authors:  Alejandro Ferrer; Abhishek A Mangaonkar; Mrinal M Patnaik
Journal:  Curr Hematol Malig Rep       Date:  2022-05-07       Impact factor: 4.213

4.  Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening.

Authors:  Mariarosaria de Rosa; Sanjana A Thosar; Ryan P Barnes; Ariana C Detwiler; Vera Roginskaya; Bennett Van Houten; Marcel P Bruchez; Jacob Stewart-Ornstein; Patricia L Opresko
Journal:  Nat Struct Mol Biol       Date:  2022-06-30       Impact factor: 18.361

5.  Telomere Dysfunction Is Associated with Altered DNA Organization in Trichoplein/Tchp/Mitostatin (TpMs) Depleted Cells.

Authors:  Angela Lauriola; Pierpaola Davalli; Gaetano Marverti; Andrea Caporali; Sabine Mai; Domenico D'Arca
Journal:  Biomedicines       Date:  2022-07-05

6.  The relation between sensory processing sensitivity and telomere length in adolescents.

Authors:  Armin Jentsch; Frances Hoferichter; Diana Raufelder; Geja Hageman; Lou Maas
Journal:  Brain Behav       Date:  2022-08-29       Impact factor: 3.405

7.  The Interplay between Telomeres, Mitochondria, and Chronic Stress Exposure in the Aging Egg.

Authors:  Aksinya Derevyanko; Agnieszka Skowronska; Mariusz T Skowronski; Paweł Kordowitzki
Journal:  Cells       Date:  2022-08-22       Impact factor: 7.666

8.  Physical Activity on Telomere Length as a Biomarker for Aging: A Systematic Review.

Authors:  Marlies Schellnegger; Alvin C Lin; Niels Hammer; Lars-Peter Kamolz
Journal:  Sports Med Open       Date:  2022-09-04

Review 9.  Tea Polyphenols as Prospective Natural Attenuators of Brain Aging.

Authors:  Mengyu Hong; Jing Yu; Xuanpeng Wang; Yanan Liu; Shengnan Zhan; Zufang Wu; Xin Zhang
Journal:  Nutrients       Date:  2022-07-22       Impact factor: 6.706

10.  Genetic association of leukocyte telomere length with Graves' disease in Biobank Japan: A two-sample Mendelian randomization study.

Authors:  Meijie Ye; Yu Wang; Yiqiang Zhan
Journal:  Front Immunol       Date:  2022-09-29       Impact factor: 8.786
  10 in total

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