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Literature DB >> 3353223

Automated sequence reading and analysis.

Abstract

We report on a system developed by Bio-Rad Laboratories, Inc. which combines automated reading of DNA sequencing autoradiograms with comprehensive software for shotgun overlapping of the readings, analysis of the sequences derived and searching of databases. Reading is accomplished using a high speed optical scanner and pattern recognition software operating on a personal computer. Overlapping, analysis and database searching software each incorporate significant advances over prior systems.

Mesh：

Year: 1988 PMID： 3353223 PMCID： PMC338179 DOI： 10.1093/nar/16.5.1847

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

14 in total

1. Automatic reading of DNA sequencing gel autoradiographs using a large format digital scanner.

Authors: J K Elder; D K Green; E M Southern
Journal: Nucleic Acids Res Date: 1986-01-10 Impact factor: 16.971

2. A strategy of DNA sequencing employing computer programs.

Authors: R Staden
Journal: Nucleic Acids Res Date: 1979-06-11 Impact factor: 16.971

3. A general method applicable to the search for similarities in the amino acid sequence of two proteins.

Authors: S B Needleman; C D Wunsch
Journal: J Mol Biol Date: 1970-03 Impact factor: 5.469

4. A computer program to enter DNA gel reading data into a computer.

Authors: R Staden
Journal: Nucleic Acids Res Date: 1984-01-11 Impact factor: 16.971

5. An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences.

Authors: R Staden
Journal: Nucleic Acids Res Date: 1982-05-11 Impact factor: 16.971

6. Further procedures for sequence analysis by computer.

Authors: R Staden
Journal: Nucleic Acids Res Date: 1978-03 Impact factor: 16.971

7. A computer program to search for tRNA genes.

Authors: R Staden
Journal: Nucleic Acids Res Date: 1980-02-25 Impact factor: 16.971

8. A new computer method for the storage and manipulation of DNA gel reading data.

Authors: R Staden
Journal: Nucleic Acids Res Date: 1980-08-25 Impact factor: 16.971

9. Automation of the computer handling of gel reading data produced by the shotgun method of DNA sequencing.

Authors: R Staden
Journal: Nucleic Acids Res Date: 1982-08-11 Impact factor: 16.971

10. Sequence data handling by computer.

Authors: R Staden
Journal: Nucleic Acids Res Date: 1977-11 Impact factor: 16.971

2 in total

1. Finding errors in DNA sequences.

Authors: J Posfai; R J Roberts
Journal: Proc Natl Acad Sci U S A Date: 1992-05-15 Impact factor: 11.205

2. An adaptive, object oriented strategy for base calling in DNA sequence analysis.

Authors: M C Giddings; R L Brumley; M Haker; L M Smith
Journal: Nucleic Acids Res Date: 1993-09-25 Impact factor: 16.971

2 in total