J van Loon1,2,3, A M J S Vervest3, H M van der Vis1, I N Sierevelt1,4, D C Baas3, K T M Opdam2, G M M J Kerkhoffs2, D Haverkamp5. 1. Department of Orthopedic Surgery, Xpert Clinics/SCORE (Specialized Center of Orthopedic Research and Education), Laarderhoogtweg 12, 1101EA, Amsterdam, The Netherlands. 2. Department of Orthopaedic Surgery, Amsterdam University Medical Centers, location Academic Medical Center, Meibergdreef 15, 1105, AZ, Amsterdam, The Netherlands. 3. Department of Orthopaedic Surgery, Tergooi, Van Riebeeckweg 212, 1213, XZ, Hilversum, The Netherlands. 4. Department of Orthopaedic Surgery, Spaarne Gasthuis, Spaarnepoort 1, 2134, TM, Hoofddorp, The Netherlands. 5. Department of Orthopedic Surgery, Xpert Clinics/SCORE (Specialized Center of Orthopedic Research and Education), Laarderhoogtweg 12, 1101EA, Amsterdam, The Netherlands. d.haverkamp@xpertorthopedie.nl.
Abstract
PURPOSE: In press-fit total hip arthroplasty (THA), primary stability is needed to avoid micromotion and hereby aseptic loosening, the main reason for early revision. High aseptic loosening revision rates of the seleXys TH+ cup (Mathys Medical) with Ceramys ceramic-on-ceramic (CoC) bearing are seen in literature. Since CoC is presumed to overcome long-term wear-related revisions, the reason for early failure of this cup is important to clarify. The aim is to investigate its ten year outcomes and differentiate between potential causes and identify risk factors for aseptic loosening. METHODS: Retrospective screening of a prospectively documented series of 315 THAs was performed. Primary outcome was cumulative incidence of cup revision due to aseptic loosening. Secondary outcomes were component revision and reoperation. Additionally, potential predictive factors for aseptic loosening were evaluated. RESULTS: At the median follow-up of 9.7 years [IQR 4.4; 10.3], 48 TH+ (15.2%) were revised due to aseptic loosening. Competing risk analysis showed a ten year cumulative incidence of cup revision due to aseptic loosening of 15.6% (95% CI 12.0-20.2). Stabilization of early revision rates was observed, following a high rate of respectively 81.3% (n = 39) and 95.8% (n = 46) within the first two and three years. No significant predictive factors for aseptic loosening were found. CONCLUSION: The ten year results of seleXys TH+ cup with Ceramys CoC bearing showed an unacceptable high aseptic loosening rate, which stabilized over time after a high early failure incidence. This could be attributed to a problem with osseointegration during the transition of primary to definitive stability.
PURPOSE: In press-fit total hip arthroplasty (THA), primary stability is needed to avoid micromotion and hereby aseptic loosening, the main reason for early revision. High aseptic loosening revision rates of the seleXys TH+ cup (Mathys Medical) with Ceramys ceramic-on-ceramic (CoC) bearing are seen in literature. Since CoC is presumed to overcome long-term wear-related revisions, the reason for early failure of this cup is important to clarify. The aim is to investigate its ten year outcomes and differentiate between potential causes and identify risk factors for aseptic loosening. METHODS: Retrospective screening of a prospectively documented series of 315 THAs was performed. Primary outcome was cumulative incidence of cup revision due to aseptic loosening. Secondary outcomes were component revision and reoperation. Additionally, potential predictive factors for aseptic loosening were evaluated. RESULTS: At the median follow-up of 9.7 years [IQR 4.4; 10.3], 48 TH+ (15.2%) were revised due to aseptic loosening. Competing risk analysis showed a ten year cumulative incidence of cup revision due to aseptic loosening of 15.6% (95% CI 12.0-20.2). Stabilization of early revision rates was observed, following a high rate of respectively 81.3% (n = 39) and 95.8% (n = 46) within the first two and three years. No significant predictive factors for aseptic loosening were found. CONCLUSION: The ten year results of seleXys TH+ cup with Ceramys CoC bearing showed an unacceptable high aseptic loosening rate, which stabilized over time after a high early failure incidence. This could be attributed to a problem with osseointegration during the transition of primary to definitive stability.
Entities:
Keywords:
Aseptic loosening; Ceramic-on-ceramic; Early failure; Primary stability; Total hip arthroplasty
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