| Literature DB >> 33275154 |
Sara Scardera1,2, Léa C Perret1, Isabelle Ouellet-Morin3,4, Geneviève Gariépy4,5, Robert-Paul Juster4,6, Michel Boivin7, Gustavo Turecki1, Richard E Tremblay8,9, Sylvana Côté5,9,10, Marie-Claude Geoffroy1,2.
Abstract
Importance: Mental health problems are common during the transition from adolescence to young adulthood. Although perceived social support and mental health problems have been shown to be concurrently associated, longitudinal studies are lacking to document the directionality of this association, especially in emerging adulthood (late teens to late 20s). Objective: To test whether social support in emerging adulthood protects against later depression, anxiety, and suicidal ideation and suicide attempts after adjusting for a range of confounders, including prior mental health problems and family characteristics. Design, Setting, and Participants: This population-based cohort study included 1174 participants from the Quebec Longitudinal Study of Child Development. Participants underwent yearly or biennial assessment (starting from age 5 months to age 20 years). Data were collected from March 16, 1998, through June 1, 2018. Main Outcomes and Measures: Self-reported perceived social support was measured at age 19 years using the 10-item Social Provision Scale. Mental health problems, including depressive and anxiety symptoms as well as suicidal ideation and attempts, were measured at age 20 years. Social support and mental health problem raw scores were converted to z-scores to ease interpretation. Depressive and anxiety symptoms were categorized using validated cutoffs to determine clinical significance.Entities:
Year: 2020 PMID: 33275154 PMCID: PMC7718598 DOI: 10.1001/jamanetworkopen.2020.27491
Source DB: PubMed Journal: JAMA Netw Open ISSN: 2574-3805
Descriptive Statistics for Social Support and Mental Health Problems and Suicide-Related Outcomes at Age 20 Years Based on Weighted Values
| Total (N = 1174) | Males (n = 600) | Females (n = 574) | ||
|---|---|---|---|---|
| Social support, mean (SD) | 26.70 (4.05) | 26.36 (4.27) | 27.06 (3.80) | .003 |
| Depressive symptoms, mean (SD) | 9.10 (6.40) | 8.14 (6.21) | 10.11 (6.44) | <.001 |
| Depression, No. (%) | <.001 | |||
| Moderate symptoms | 289 (24.6) | 110 (18.3) | 179 (31.2) | NA |
| Severe symptoms | 67 (5.7) | 26 (4.3) | 41 (7.1) | NA |
| Anxiety symptoms, mean (SD) | 4.53 (4.64) | 3.52 (4.27) | 5.60 (4.79) | <.001 |
| Anxiety, No. (%) | <.001 | |||
| Moderate symptoms | 100 (8.5) | 23 (3.8) | 77 (13.4) | NA |
| Severe symptoms | 61 (5.2) | 23 (3.8) | 38 (6.6) | NA |
| Suicidal ideation, No. (%) | 121 (10.3) | 61 (10.2) | 60 (10.5) | .87 |
| Suicide attempts, No. (%) | 30 (2.5) | 15 (2.5) | 15 (2.6) | .90 |
Abbreviaton: NA, not applicable.
Data were compiled from the final master file of the Québec Longitudinal Study of Child Development (1998–2018), Québec Government, Québec Statistic Institute.
Based on t tests or χ2 (none, moderate, and severe).
Raw scores with a mean (SD) of 0 (1).
Moderate symptoms were defined by Centre for Epidemiological Studies Depression scale scores of 12 to 20, with a maximum score of 36 and Generalized Anxiety Disorder 7-item scale scores of 10 to 14, with a maximum score of 21.
Severe symptoms were defined by Centre for Epidemiological Studies-Depression scale scores of 21 or higher and Generalized Anxiety Disorder 7-item scale scores of 15 or higher.
Associations Between Social Support at Age 19 Years and Mental Health Problems and Suicide-Related Outcomes at 20 Years (N = 1174), Imputed Values
| Model | Depressive symptoms | Anxiety symptoms | OR (95% CI) | |||
|---|---|---|---|---|---|---|
| β (95% CI) | β (95% CI) | Suicidal ideation | Suicide attempts | |||
| Social support adjusted for sex | −0.32 (−0.37 to −0.26) | <.001 | −0.18 (−0.23 to −0.12) | <.001 | 0.56 (0.48 to 0.66) | 0.56 (0.45 to 0.70) |
| Social support adjusted for all other confounders | −0.23 (−0.26 to −0.18) | <.001 | −0.10 (−0.15 to −0.04) | <.001 | 0.59 (0.50 to 0.70) | 0.60 (0.46 to 0.79) |
Abbreviation: OR, odds ratio.
Data were compiled from the final master file of the Québec Longitudinal Study of Child Development (1998–2018), Québec Government, Québec Statistic Institute.
The fully adjusted model is additionally adjusted for mental health problems in adolescence (ages 15-17 years), including anxiety, depression, suicidal ideation/attempts, attention deficit/hyperactivity-impulsivity, oppositional defiant and conduct symptoms, and for family characteristics in adolescence, including socioeconomic status, family functioning, and family structure (at age 17 years).
Prospective Associations Between Social Support at 19 Years and Clinical Thresholds of Mental Health Problems at 20 Years (N = 1174), Imputed Values
| Model | OR (95% CI) | |||
|---|---|---|---|---|
| Depressive symptoms | Anxiety symptoms | |||
| Moderate | Severe | Moderate | Severe | |
| Social support adjusted for sex | 0.61 (0.53-0.70) | 0.47 (0.39-0.58) | 0.74 (0.62-0.88) | 0.68 (0.56-0.83) |
| Social support adjusted for all other confounders | 0.67 (0.58-0.78) | 0.53 (0.42-0.66) | 0.84 (0.69-1.02) | 0.78 (0.62-0.98) |
Abbreviation: OR, odds ratio.
Data were compiled from the final master file of the Québec Longitudinal Study of Child Development (1998–2018), Québec Government, Québec Statistic Institute.
The fully adjusted model is additionally adjusted for mental health problems during adolescence (ages 15-17 years), including anxiety, depression, suicidal ideation and suicide attempts, attention deficit/hyperactivity-impulsivity, oppositional defiant and conduct symptoms as well as family characteristics in adolescence, including socioeconomic status, family functioning, and family structure (at age 17 years). Reference category: no or minimal symptoms for depressive and anxiety symptoms.