Literature DB >> 3137631

Tests of functional equivalence between pimozide pretreatment, extinction and free feeding.

P Willner1, K Chawla, D Sampson, S Sophokleous, R Muscat.   

Abstract

Both pimozide pretreatment and free feeding caused within-session and between-session decrements in variable interval operant performance; response decrements generated under pimozide were maintained on transfer to free feeding, and vice versa. On subsequently testing under extinction conditions (after food deprivation and drug free) large initial increases in responding were seen in all groups, and subsequent response decrements in extinction were steeper than in either pimozide or free feeding conditions. The effects of pimozide pretreatment do not resemble those of extinction, but may in some circumstances be functionally equivalent to a decrease in drive level.

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Year:  1988        PMID： 3137631     DOI： 10.1007/bf00181960

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  29 in total

1.  Pimozide-induced extinction of intracranial self-stimulation: response patterns rule out motor or performance deficits.

Authors:  G Fouriezos; R A Wise
Journal:  Brain Res       Date:  1976-02-20       Impact factor: 3.252

2.  Effects of pre-feeding on food-approach latency and food consumption speed in food deprived rats.

Authors:  R A Wise; L Raptis
Journal:  Physiol Behav       Date:  1985-12

3.  Major attenuation of food reward with performance-sparing doses of pimozide in the rat.

Authors:  R A Wise; J Spindler; L Legault
Journal:  Can J Psychol       Date:  1978-06

4.  Some effects of pimozide on nondeprived rats' lever pressing maintained by a sucrose reward in an anhedonia paradigm.

Authors:  S E Gramling; S C Fowler; J P Tizzano
Journal:  Pharmacol Biochem Behav       Date:  1987-05       Impact factor: 3.533

5.  Pimozide and amphetamine have opposing effects on the reward summation function.

Authors:  C R Gallistel; D Karras
Journal:  Pharmacol Biochem Behav       Date:  1984-01       Impact factor: 3.533

6.  Effects of extinction, pimozide, SCH 23390, and metoclopramide on food-rewarded operant responding of rats.

Authors:  R J Beninger; M Cheng; B L Hahn; D C Hoffman; E J Mazurski; M A Morency; P Ramm; R J Stewart
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

7.  A comparison of the effects of pimozide and nonreinforcement on discriminated operant responding in rats.

Authors:  R J Beninger
Journal:  Pharmacol Biochem Behav       Date:  1982-04       Impact factor: 3.533

Review 8.  The role of dopamine in locomotor activity and learning.

Authors:  R J Beninger
Journal:  Brain Res       Date:  1983-10       Impact factor: 3.252

9.  Neuroleptic-induced "anhedonia" in rats: pimozide blocks reward quality of food.

Authors:  R A Wise; J Spindler; H deWit; G J Gerberg
Journal:  Science       Date:  1978-07-21       Impact factor: 47.728

10.  Effects of haloperidol and d-amphetamine on perceived quantity of food and tones.

Authors:  M T Martin-Iverson; D Wilkie; H C Fibiger
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530
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  9 in total

1.  Behavioural tests of the dopamine depletion hypothesis of neuroleptic-induced response decrement.

Authors:  P Willner; G Phillips; R Muscat; P Hood
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

2.  A matching law analysis of the effects of dopamine receptor antagonists.

Authors:  P Willner; D Sampson; G Phillips; R Muscat
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

Review 3.  The behavioral pharmacology of effort-related choice behavior: dopamine, adenosine and beyond.

Authors:  John D Salamone; Merce Correa; Eric J Nunes; Patrick A Randall; Marta Pardo
Journal:  J Exp Anal Behav       Date:  2012-01       Impact factor: 2.468

4.  Motivational states influence effort-based decision making in rats: the role of dopamine in the nucleus accumbens.

Authors:  Bettina Mai; Susanne Sommer; Wolfgang Hauber
Journal:  Cogn Affect Behav Neurosci       Date:  2012-03       Impact factor: 3.282

5.  Dopamine receptor blockade attenuates the general incentive motivational effects of noncontingently delivered rewards and reward-paired cues without affecting their ability to bias action selection.

Authors:  Sean B Ostlund; Nigel T Maidment
Journal:  Neuropsychopharmacology       Date:  2011-09-14       Impact factor: 7.853

6.  Limited encoding of effort by dopamine neurons in a cost-benefit trade-off task.

Authors:  Benjamin Pasquereau; Robert S Turner
Journal:  J Neurosci       Date:  2013-05-08       Impact factor: 6.167

7.  Extracellular dopamine levels in striatal subregions track shifts in motivation and response cost during instrumental conditioning.

Authors:  Sean B Ostlund; Kate M Wassum; Niall P Murphy; Bernard W Balleine; Nigel T Maidment
Journal:  J Neurosci       Date:  2011-01-05       Impact factor: 6.167

8.  Differential dependence of Pavlovian incentive motivation and instrumental incentive learning processes on dopamine signaling.

Authors:  Kate M Wassum; Sean B Ostlund; Bernard W Balleine; Nigel T Maidment
Journal:  Learn Mem       Date:  2011-06-21       Impact factor: 2.460

9.  Dopamine D1 and D2 antagonists attenuate amphetamine-produced enhancement of responding for conditioned reward in rats.

Authors:  R Ranaldi; R J Beninger
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530
  9 in total

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