Literature DB >> 30670435

Efficacy of Tedizolid against Enterococci and Staphylococci, Including cfr + Strains, in a Mouse Peritonitis Model.

Kavindra V Singh1,2, Cesar A Arias3,4,5,2,6, Barbara E Murray3,4,2.   

Abstract

In a mouse peritonitis model, tedizolid was comparable to linezolid and daptomycin against an Enterococcus faecium strain (VANr, AMPr), an Enterococcus faecalis strain, and a methicillin-resistant Staphylococcus aureus (MRSA) strain with and without cfr Against a cfr(B)+ E. faecium, tedizolid was inferior in vivo to linezolid and daptomycin, despite an ∼4-fold lower MIC.
Copyright © 2019 American Society for Microbiology.

Entities:  

Keywords:  mouse peritonitis; tedizolid

Mesh：

Substances：

Year:  2019        PMID： 30670435      PMCID： PMC6437489          DOI： 10.1128/AAC.02627-18

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  26 in total

1.  Intra- and extracellular activity of linezolid against Staphylococcus aureus in vivo and in vitro.

Authors:  Anne Sandberg; Klaus Skovbo Jensen; Pierre Baudoux; Françoise Van Bambeke; Paul M Tulkens; Niels Frimodt-Møller
Journal:  J Antimicrob Chemother       Date:  2010-03-07       Impact factor: 5.790

2.  Comparative In Vivo Efficacies of Tedizolid in Neutropenic versus Immunocompetent Murine Streptococcus pneumoniae Lung Infection Models.

Authors:  Kamilia Abdelraouf; David P Nicolau
Journal:  Antimicrob Agents Chemother       Date:  2016-12-27       Impact factor: 5.191

3.  Generation of restriction map of Enterococcus faecalis OG1 and investigation of growth requirements and regions encoding biosynthetic function.

Authors:  B E Murray; K V Singh; R P Ross; J D Heath; G M Dunny; G M Weinstock
Journal:  J Bacteriol       Date:  1993-08       Impact factor: 3.490

4.  Dissecting the mechanisms of linezolid resistance in a Drosophila melanogaster infection model of Staphylococcus aureus.

Authors:  Lorena Diaz; Dimitrios P Kontoyiannis; Diana Panesso; Nathaniel D Albert; Kavindra V Singh; Truc T Tran; Jose M Munita; Barbara E Murray; Cesar A Arias
Journal:  J Infect Dis       Date:  2013-04-01       Impact factor: 5.226

5.  Efficacy of ampicillin versus trimethoprim-sulfamethoxazole in a mouse model of lethal enterococcal peritonitis.

Authors:  C E Chenoweth; K A Robinson; D R Schaberg
Journal:  Antimicrob Agents Chemother       Date:  1990-09       Impact factor: 5.191

6.  Tedizolid phosphate vs linezolid for treatment of acute bacterial skin and skin structure infections: the ESTABLISH-1 randomized trial.

Authors:  Philippe Prokocimer; Carisa De Anda; Edward Fang; Purvi Mehra; Anita Das
Journal:  JAMA       Date:  2013-02-13       Impact factor: 56.272

7.  Comparative Efficacies of Tedizolid Phosphate, Linezolid, and Vancomycin in a Murine Model of Subcutaneous Catheter-Related Biofilm Infection Due to Methicillin-Susceptible and -Resistant Staphylococcus aureus.

Authors:  Arnold S Bayer; Wessam Abdelhady; Liang Li; Rachelle Gonzales; Yan Q Xiong
Journal:  Antimicrob Agents Chemother       Date:  2016-07-22       Impact factor: 5.191

8.  In vitro activity of TR-700, the antibacterial moiety of the prodrug TR-701, against linezolid-resistant strains.

Authors:  K J Shaw; S Poppe; R Schaadt; V Brown-Driver; J Finn; C M Pillar; D Shinabarger; G Zurenko
Journal:  Antimicrob Agents Chemother       Date:  2008-10-06       Impact factor: 5.191

9.  In vitro activity of TR-700, the active ingredient of the antibacterial prodrug TR-701, a novel oxazolidinone antibacterial agent.

Authors:  Ronda Schaadt; Debora Sweeney; Dean Shinabarger; Gary Zurenko
Journal:  Antimicrob Agents Chemother       Date:  2009-06-15       Impact factor: 5.191

10.  Evaluation of ceftobiprole medocaril against Enterococcus faecalis in a mouse peritonitis model.

Authors:  Cesar A Arias; Kavindra V Singh; Diana Panesso; Barbara E Murray
Journal:  J Antimicrob Chemother       Date:  2007-07-02       Impact factor: 5.790
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  6 in total

Review 1.  Resistance in Vancomycin-Resistant Enterococci.

Authors:  William R Miller; Barbara E Murray; Louis B Rice; Cesar A Arias
Journal:  Infect Dis Clin North Am       Date:  2020-12       Impact factor: 5.982

2.  Tedizolid as Step-Down Therapy following Daptomycin versus Continuation of Daptomycin against Enterococci and Methicillin- and Vancomycin-Resistant Staphylococcus aureus in a Rat Endocarditis Model.

Authors:  Kavindra V Singh; Cesar A Arias; Barbara E Murray
Journal:  Antimicrob Agents Chemother       Date:  2020-04-21       Impact factor: 5.191

3.  Efficacy of Omadacycline against Multidrug-Resistant Enterococcus faecium Strains in a Mouse Peritonitis Model.

Authors:  Kavindra V Singh; Cesar A Arias; Barbara E Murray
Journal:  Antimicrob Agents Chemother       Date:  2021-08-17       Impact factor: 5.191

4.  Phenotypic and genotypic characterization of linezolid-resistant Enterococcus faecium from the USA and Pakistan.

Authors:  Kate E Wardenburg; Robert F Potter; Alaric W D'Souza; Tahir Hussain; Meghan A Wallace; Saadia Andleeb; Carey-Ann D Burnham; Gautam Dantas
Journal:  J Antimicrob Chemother       Date:  2019-12-01       Impact factor: 5.790

Review 5.  Staphylococcus aureus Host Tropism and Its Implications for Murine Infection Models.

Authors:  Daniel M Mrochen; Liliane M Fernandes de Oliveira; Dina Raafat; Silva Holtfreter
Journal:  Int J Mol Sci       Date:  2020-09-25       Impact factor: 5.923

6.  Pharmacokinetic/Pharmacodynamic Analysis of Tedizolid Phosphate Compared to Linezolid for the Treatment of Infections Caused by Gram-Positive Bacteria.

Authors:  Alicia Rodríguez-Gascón; Amaia Aguirre-Quiñonero; María Angeles Solinís Aspiazu; Andrés Canut-Blasco
Journal:  Antibiotics (Basel)       Date:  2021-06-22
  6 in total

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