Literature DB >> 27297485

Comparative Efficacies of Tedizolid Phosphate, Linezolid, and Vancomycin in a Murine Model of Subcutaneous Catheter-Related Biofilm Infection Due to Methicillin-Susceptible and -Resistant Staphylococcus aureus.

Arnold S Bayer1, Wessam Abdelhady2, Liang Li2, Rachelle Gonzales2, Yan Q Xiong3.   

Abstract

Tedizolid, a novel oxazolidinone, exhibits bacteriostatic activity through inhibition of protein synthesis. The efficacies of tedizolid, linezolid, and vancomycin were compared in a murine catheter-related biofilm infection caused by methicillin-susceptible and -resistant Staphylococcus aureus (MSSA and MRSA, respectively) strains engineered for bioluminescence. We observed significantly improved efficacy in terms of decreased S. aureus densities and bioluminescent signals in the tedizolid-treated group versus the linezolid- and vancomycin-treated groups in the model of infection caused by the MSSA and MRSA strains.
Copyright © 2016, American Society for Microbiology. All Rights Reserved.

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Year:  2016        PMID： 27297485      PMCID： PMC4958216          DOI： 10.1128/AAC.00880-16

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  24 in total

1.  Real-time in vivo bioluminescent imaging for evaluating the efficacy of antibiotics in a rat Staphylococcus aureus endocarditis model.

Authors:  Yan Q Xiong; Julie Willard; Jagath L Kadurugamuwa; Jun Yu; Kevin P Francis; Arnold S Bayer
Journal:  Antimicrob Agents Chemother       Date:  2005-01       Impact factor: 5.191

2.  Combinatorial phenotypic signatures distinguish persistent from resolving methicillin-resistant Staphylococcus aureus bacteremia isolates.

Authors:  Kati Seidl; Arnold S Bayer; Vance G Fowler; James A McKinnell; Wessam Abdel Hady; George Sakoulas; Michael R Yeaman; Yan Q Xiong
Journal:  Antimicrob Agents Chemother       Date:  2010-11-22       Impact factor: 5.191

3.  In vitro activity of tedizolid against staphylococci isolated from prosthetic joint infections.

Authors:  Suzannah M Schmidt-Malan; Kerryl E Greenwood Quaintance; Melissa J Karau; Robin Patel
Journal:  Diagn Microbiol Infect Dis       Date:  2016-01-12       Impact factor: 2.803

Review 4.  Tedizolid: A New Oxazolidinone Antibiotic for Skin and Soft Tissue Infections.

Authors:  Elias B Chahine; Allana J Sucher; Shannon D Knutsen
Journal:  Consult Pharm       Date:  2015-07

Review 5.  Staphylococcus aureus: a well-armed pathogen.

Authors:  G L Archer
Journal:  Clin Infect Dis       Date:  1998-05       Impact factor: 9.079

6.  Telavancin in therapy of experimental aortic valve endocarditis in rabbits due to daptomycin-nonsusceptible methicillin-resistant Staphylococcus aureus.

Authors:  Yan Q Xiong; Wessam Abdel Hady; Arnold S Bayer; Liang Chen; Barry N Kreiswirth; Soo-Jin Yang
Journal:  Antimicrob Agents Chemother       Date:  2012-08-13       Impact factor: 5.191

7.  Emergence of vancomycin resistance in Staphylococcus aureus. Glycopeptide-Intermediate Staphylococcus aureus Working Group.

Authors:  T L Smith; M L Pearson; K R Wilcox; C Cruz; M V Lancaster; B Robinson-Dunn; F C Tenover; M J Zervos; J D Band; E White; W R Jarvis
Journal:  N Engl J Med       Date:  1999-02-18       Impact factor: 91.245

8.  Efficacy of telavancin in a murine model of pneumonia induced by methicillin-susceptible Staphylococcus aureus.

Authors:  Sharath S Hegde; Noe Reyes; Robert Skinner; Stacey Difuntorum
Journal:  J Antimicrob Chemother       Date:  2007-11-09       Impact factor: 5.790

9.  Direct continuous method for monitoring biofilm infection in a mouse model.

Authors:  Jagath L Kadurugamuwa; Lin Sin; Eddie Albert; Jun Yu; Kevin Francis; Monica DeBoer; Michael Rubin; Carole Bellinger-Kawahara; T R Parr; Pamela R Contag
Journal:  Infect Immun       Date:  2003-02       Impact factor: 3.441

10.  Development of real-time in vivo imaging of device-related Staphylococcus epidermidis infection in mice and influence of animal immune status on susceptibility to infection.

Authors:  Cuong Vuong; Stanislava Kocianova; Jun Yu; Jagath L Kadurugamuwa; Michael Otto
Journal:  J Infect Dis       Date:  2008-07-15       Impact factor: 5.226
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  9 in total

1.  A Human Biofilm-Disrupting Monoclonal Antibody Potentiates Antibiotic Efficacy in Rodent Models of both Staphylococcus aureus and Acinetobacter baumannii Infections.

Authors:  Yan Q Xiong; Angeles Estellés; L Li; W Abdelhady; R Gonzales; Arnold S Bayer; Edgar Tenorio; Anton Leighton; Stefan Ryser; Lawrence M Kauvar
Journal:  Antimicrob Agents Chemother       Date:  2017-09-22       Impact factor: 5.191

2.  Efficacy of Tedizolid against Enterococci and Staphylococci, Including cfr + Strains, in a Mouse Peritonitis Model.

Authors:  Kavindra V Singh; Cesar A Arias; Barbara E Murray
Journal:  Antimicrob Agents Chemother       Date:  2019-03-27       Impact factor: 5.191

3.  Activity of Tedizolid in Methicillin-Resistant Staphylococcus epidermidis Experimental Foreign Body-Associated Osteomyelitis.

Authors:  Kyung-Hwa Park; Kerryl E Greenwood-Quaintance; Audrey N Schuetz; Jayawant N Mandrekar; Robin Patel
Journal:  Antimicrob Agents Chemother       Date:  2017-01-24       Impact factor: 5.191

4.  In Vivo Bioluminescent Monitoring of Therapeutic Efficacy and Pharmacodynamic Target Assessment of Antofloxacin against Escherichia coli in a Neutropenic Murine Thigh Infection Model.

Authors:  Yu-Feng Zhou; Meng-Ting Tao; Yu-Zhang He; Jian Sun; Ya-Hong Liu; Xiao-Ping Liao
Journal:  Antimicrob Agents Chemother       Date:  2017-12-21       Impact factor: 5.191

Review 5.  In-vivo monitoring of infectious diseases in living animals using bioluminescence imaging.

Authors:  Pinar Avci; Mahdi Karimi; Magesh Sadasivam; Wanessa C Antunes-Melo; Elisa Carrasco; Michael R Hamblin
Journal:  Virulence       Date:  2017-12-08       Impact factor: 5.882

6.  Comparative Efficacies of Linezolid vs. Tedizolid in an Experimental Murine Model of Vancomycin-Resistant Enterococcal (VRE) Bacteremia.

Authors:  Wessam Abdelhady; Nagendra N Mishra
Journal:  Front Med (Lausanne)       Date:  2019-02-20

7.  Tedizolid phosphate for the treatment of acute bacterial skin and skin-structure infections: an evidence-based review of its place in therapy.

Authors:  Matteo Bassetti; Nadia Castaldo; Alessia Carnelutti; Maddalena Peghin; Daniele Roberto Giacobbe
Journal:  Core Evid       Date:  2019-07-05

Review 8.  Pharmacokinetics and Pharmacodynamics of Tedizolid.

Authors:  Khalid Iqbal; Aliki Milioudi; Sebastian Georg Wicha
Journal:  Clin Pharmacokinet       Date:  2022-02-07       Impact factor: 6.447

9.  A Novel Immunocompetent Mouse Model for Testing Antifungal Drugs Against Invasive Candida albicans Infection.

Authors:  Lisa K Ryan; Amy G Hise; Chowdhury Mobaswar Hossain; William Ruddick; Rezwana Parveen; Katie B Freeman; Damian G Weaver; Hema P Narra; Richard W Scott; Gill Diamond
Journal:  J Fungi (Basel)       Date:  2020-09-30
  9 in total

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