| Literature DB >> 2126692 |
C E Chenoweth1, K A Robinson, D R Schaberg.
Abstract
Lethal enterococcal peritonitis in mice was used to compare trimethoprim-sulfamethoxazole (TMP-SMX) therapy with ampicillin therapy. Peritoneal fluid showed a 10(3)-CFU decrease in enterococci with ampicillin compared with TMP-SMX. Mortality of the untreated mice was 100%, compared with 40% for ampicillin and 95% for TMP-SMX, despite adequately measured levels in serum and peritoneal fluid.Entities:
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Year: 1990 PMID: 2126692 PMCID: PMC171930 DOI: 10.1128/AAC.34.9.1800
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191