Jordi Alonso1,2,3, Gemma Vilagut1,2,3, Philippe Mortier4, Randy P Auerbach5, Ronny Bruffaerts4, Pim Cuijpers6, Koen Demyttenaere4, David D Ebert7, Edel Ennis8, Raul A Gutiérrez-García9, Jennifer Greif Green10, Penelope Hasking11, Sue Lee12, Jason Bantjes13, Matthew K Nock14, Stephanie Pinder-Amaker15, Nancy A Sampson12, Alan M Zaslavsky12, Ronald C Kessler12. 1. Health Services Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain. 2. Pompeu Fabra University (UPF), Barcelona, Spain. 3. CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, Spain. 4. Universitair Psychiatrisch Centrum-Katholieke Universiteit Leuven (UPC-KUL), Campus Gasthuisberg, Leuven, Belgium. 5. Department of Psychiatry, Columbia University, New York City, New York, USA. 6. Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. 7. Department for Psychology, Clinical Psychology and Psychotherapy, Friedrich-Alexander University Erlangen Nuremberg, Erlangen, Germany. 8. School of Psychology, Ulster University, Londonderry, UK. 9. Universidad De La Salle Bajio, Campus Salamanca, Guanajuato, Mexico. 10. School of Education, Boston University, Boston, Massachusetts, USA. 11. Curtin University, Bentley, Western Australia, Australia. 12. Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA. 13. Psychology Department, Stellenbosch University, Stellenbosch, South Africa. 14. Department of Psychology, Harvard University, Cambridge, Massachusetts, USA. 15. Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
Abstract
OBJECTIVE: The objective of this study is to assess the contribution of mental comorbidity to role impairment among college students. METHODS: Web-based self-report surveys from 14,348 first-year college students (Response Rate [RR] = 45.5%): 19 universities, eight countries of the World Mental Health International College Student Initiative. We assessed impairment (Sheehan Disability Scales and number of days out of role [DOR] in the past 30 days) and seven 12-month DSM-IV disorders. We defined six multivariate mental disorder classes using latent class analysis (LCA). We simulated population attributable risk proportions (PARPs) of impairment. RESULTS: Highest prevalence of role impairment was highest among the 1.9% of students in the LCA class with very high comorbidity and bipolar disorder (C1): 78.3% of them had severe role impairment (vs. 20.8%, total sample). Impairment was lower in two other comorbid classes (C2 and C3) and successively lower in the rest. A similar monotonic pattern was found for DOR. Both LCA classes and some mental disorders (major depression and panic, in particular) were significant predictors of role impairment. PARP analyses suggest that eliminating all mental disorders might reduce severe role impairment by 64.6% and DOR by 44.3%. CONCLUSIONS: Comorbid mental disorders account for a substantial part of role impairment in college students.
OBJECTIVE: The objective of this study is to assess the contribution of mental comorbidity to role impairment among college students. METHODS: Web-based self-report surveys from 14,348 first-year college students (Response Rate [RR] = 45.5%): 19 universities, eight countries of the World Mental Health International College Student Initiative. We assessed impairment (Sheehan Disability Scales and number of days out of role [DOR] in the past 30 days) and seven 12-month DSM-IV disorders. We defined six multivariate mental disorder classes using latent class analysis (LCA). We simulated population attributable risk proportions (PARPs) of impairment. RESULTS: Highest prevalence of role impairment was highest among the 1.9% of students in the LCA class with very high comorbidity and bipolar disorder (C1): 78.3% of them had severe role impairment (vs. 20.8%, total sample). Impairment was lower in two other comorbid classes (C2 and C3) and successively lower in the rest. A similar monotonic pattern was found for DOR. Both LCA classes and some mental disorders (major depression and panic, in particular) were significant predictors of role impairment. PARP analyses suggest that eliminating all mental disorders might reduce severe role impairment by 64.6% and DOR by 44.3%. CONCLUSIONS: Comorbid mental disorders account for a substantial part of role impairment in college students.
Authors: Jordi Alonso; Gemma Vilagut; Philippe Mortier; Randy P Auerbach; Ronny Bruffaerts; Pim Cuijpers; Koen Demyttenaere; David D Ebert; Edel Ennis; Raul A Gutiérrez-García; Jennifer Greif Green; Penelope Hasking; Sue Lee; Jason Bantjes; Matthew K Nock; Stephanie Pinder-Amaker; Nancy A Sampson; Alan M Zaslavsky; Ronald C Kessler Journal: Int J Methods Psychiatr Res Date: 2018-11-06 Impact factor: 4.035
Authors: R C Kessler; J R Calabrese; P A Farley; M J Gruber; M A Jewell; W Katon; P E Keck; A A Nierenberg; N A Sampson; M K Shear; A C Shillington; M B Stein; M E Thase; H-U Wittchen Journal: Psychol Med Date: 2012-10-18 Impact factor: 7.723
Authors: Ronald C Kessler; G Paul Amminger; Sergio Aguilar-Gaxiola; Jordi Alonso; Sing Lee; T Bedirhan Ustün Journal: Curr Opin Psychiatry Date: 2007-07 Impact factor: 4.741
Authors: David H Barlow; Todd J Farchione; Jacqueline R Bullis; Matthew W Gallagher; Heather Murray-Latin; Shannon Sauer-Zavala; Kate H Bentley; Johanna Thompson-Hollands; Laren R Conklin; James F Boswell; Amantia Ametaj; Jenna R Carl; Hannah T Boettcher; Clair Cassiello-Robbins Journal: JAMA Psychiatry Date: 2017-09-01 Impact factor: 21.596
Authors: Mathias Harrer; Sophia Helen Adam; Rebecca Jessica Fleischmann; Harald Baumeister; Randy Auerbach; Ronny Bruffaerts; Pim Cuijpers; Ronald C Kessler; Matthias Berking; Dirk Lehr; David Daniel Ebert Journal: J Med Internet Res Date: 2018-04-23 Impact factor: 5.428
Authors: Jordi Alonso; Gemma Vilagut; Philippe Mortier; Randy P Auerbach; Ronny Bruffaerts; Pim Cuijpers; Koen Demyttenaere; David D Ebert; Edel Ennis; Raul A Gutiérrez-García; Jennifer Greif Green; Penelope Hasking; Sue Lee; Jason Bantjes; Matthew K Nock; Stephanie Pinder-Amaker; Nancy A Sampson; Alan M Zaslavsky; Ronald C Kessler Journal: Int J Methods Psychiatr Res Date: 2018-11-06 Impact factor: 4.035
Authors: Chelsey R Wilks; Randy P Auerbach; Jordi Alonso; Corina Benjet; Ronny Bruffaerts; Pim Cuijpers; David D Ebert; Jennifer G Green; Claude A Mellins; Philippe Mortier; Ekaterina Sadikova; Nancy A Sampson; Ronald C Kessler Journal: J Psychiatr Res Date: 2020-01-29 Impact factor: 4.791
Authors: Arthur D P Mak; Sue Lee; Nancy A Sampson; Yesica Albor; Jordi Alonso; Randy P Auerbach; Harald Baumeister; Corina Benjet; Ronny Bruffaerts; Pim Cuijpers; David D Ebert; Raúl A Gutierrez-Garcia; Penelope Hasking; Coral Lapsley; Christine Lochner; Ronald C Kessler Journal: J Atten Disord Date: 2021-11-10 Impact factor: 3.196
Authors: Guilherme Borges; Ricardo Orozco; Corina Benjet; Kalina I Mart Inez Mart Inez; Eunice Vargas Contreras; Ana Lucia Jim Enez P Erez; Alvaro Julio Pel Aez Cedr Es; Praxedis Cristina Hern Andez Uribe; Mar Ia Anabell Covarrubias D Iaz Couder; Ra Ul A Gutierrez-Garcia; Guillermo E Quevedo Ch Avez; Yesica Albor; Enrique Mendez; Maria Elena Medina-Mora; Philippe Mortier; Jos E Luis Ayuso-Mateos Journal: Can J Psychiatry Date: 2020-08-18 Impact factor: 4.356
Authors: Ronny Bruffaerts; Philippe Mortier; Randy P Auerbach; Jordi Alonso; Alicia E Hermosillo De la Torre; Pim Cuijpers; Koen Demyttenaere; David D Ebert; Jennifer Greif Green; Penelope Hasking; Dan J Stein; Edel Ennis; Matthew K Nock; Stephanie Pinder-Amaker; Nancy A Sampson; Gemma Vilagut; Alan M Zaslavsky; Ronald C Kessler Journal: Int J Methods Psychiatr Res Date: 2019-01-20 Impact factor: 4.035
Authors: Eirini Karyotaki; Anke M Klein; Heleen Riper; Leonore de Wit; Lisa Krijnen; Eline Bol; Felix Bolinski; Simone Burger; David D Ebert; Randy P Auerbach; Ronald C Kessler; Ronny Bruffaerts; Neeltje Batelaan; Claudia M van der Heijde; Peter Vonk; Annet Kleiboer; Reinout W Wiers; Pim Cuijpers Journal: BMJ Open Date: 2019-05-14 Impact factor: 2.692
Authors: Pim Cuijpers; Randy P Auerbach; Corina Benjet; Ronny Bruffaerts; David Ebert; Eirini Karyotaki; Ronald C Kessler Journal: Int J Methods Psychiatr Res Date: 2019-01-09 Impact factor: 4.035
Authors: Jason Bantjes; Alan E Kazdin; Pim Cuijpers; Elsie Breet; Munita Dunn-Coetzee; Charl Davids; Dan J Stein; Ronald C Kessler Journal: JMIR Ment Health Date: 2021-05-27