Ivo Rausch1, Agustin Ruiz2, Itziar Valverde-Pascual2, Jacobo Cal-González3, Thomas Beyer3, Ignasi Carrio4. 1. QIMP Team, Center of Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria ivo.rausch@meduniwien.ac.at. 2. Department of Medical Physics and Radiation Protection, Hospital Santa Creu i Sant Pau, Barcelona, Catalonia/Spain; and. 3. QIMP Team, Center of Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria. 4. Department of Nuclear Medicine, Hospital Santa Creu i Sant Pau, Barcelona, Catalonia/Spain.
Abstract
The aim of this study was to evaluate the physical performance of the Vereos whole-body PET/CT system according to the National Electrical Manufacturers Association (NEMA) NU2-2012 standard and to compare it with other state-of-the-art PET/CT systems. Methods: Spatial resolution, sensitivity, count-rate performance, count rate accuracy, and image quality were assessed. Specifically, spatial resolution was measured using an 18F point-source. System sensitivity was calculated from acquisitions of an 18F line source inside aluminum tubes of varying thickness. Assessment of count rate performance and count rate accuracy was based on measurements of an 18F line source inside a 20-cm-diameter polyethylene cylinder. PET image quality was assessed using a NEMA IQ phantom. All measurements were performed according to the predefined and implemented NEMA NU2-2012 acquisition protocols at a clinical installation of a Vereos PET/CT system. Evaluation was performed using the software provided by the vendor. Results: The average (radial and tangential) transverse spatial resolution was 4.2, 4.5, and 5.5 mm in full width at half maximum for a 1-, 10-, and 20-cm radial offset, respectively, from the center of the field of view. Axial spatial resolution varied between 4.2 and 4.6 mm in full width at half maximum, depending on the radial source position. The average sensitivity was 5.2 cps/kBq. A peak noise-equivalent count (NEC) rate of 153.4 kcps was measured at an activity concentration of 54.9 kBq/mL. The scatter fraction at peak NEC rate was 33.9%, and the maximum count rate error at and below peak NEC rate was 6.8%. Contrast recovery coefficients varied from 54.3% (10-mm sphere) to 83.9% (22-mm sphere) for the hot spheres, and between 81.4% (28-mm sphere) and 87% (37-mm sphere) for the cold spheres for a given sphere-to-background ratio of 4:1. Conclusion: The overall performance characteristics of the Vereos PET/CT system are comparable to state-of-the-art whole-body PET/CT systems with the exception that the peak NEC rate occurs at a higher activity concentration, thus indicating the ability of the Vereos PET/CT system to cover a wider range of activities.
The aim of this study was to evaluate the physical performance of the Vereos whole-body PET/CT system according to the National Electrical Manufacturers Association (NEMA) NU2-2012 standard and to compare it with other state-of-the-art PET/CT systems. Methods: Spatial resolution, sensitivity, count-rate performance, count rate accuracy, and image quality were assessed. Specifically, spatial resolution was measured using an 18F point-source. System sensitivity was calculated from acquisitions of an 18F line source inside aluminum tubes of varying thickness. Assessment of count rate performance and count rate accuracy was based on measurements of an 18F line source inside a 20-cm-diameter polyethylene cylinder. PET image quality was assessed using a NEMA IQ phantom. All measurements were performed according to the predefined and implemented NEMA NU2-2012 acquisition protocols at a clinical installation of a Vereos PET/CT system. Evaluation was performed using the software provided by the vendor. Results: The average (radial and tangential) transverse spatial resolution was 4.2, 4.5, and 5.5 mm in full width at half maximum for a 1-, 10-, and 20-cm radial offset, respectively, from the center of the field of view. Axial spatial resolution varied between 4.2 and 4.6 mm in full width at half maximum, depending on the radial source position. The average sensitivity was 5.2 cps/kBq. A peak noise-equivalent count (NEC) rate of 153.4 kcps was measured at an activity concentration of 54.9 kBq/mL. The scatter fraction at peak NEC rate was 33.9%, and the maximum count rate error at and below peak NEC rate was 6.8%. Contrast recovery coefficients varied from 54.3% (10-mm sphere) to 83.9% (22-mm sphere) for the hot spheres, and between 81.4% (28-mm sphere) and 87% (37-mm sphere) for the cold spheres for a given sphere-to-background ratio of 4:1. Conclusion: The overall performance characteristics of the Vereos PET/CT system are comparable to state-of-the-art whole-body PET/CT systems with the exception that the peak NEC rate occurs at a higher activity concentration, thus indicating the ability of the Vereos PET/CT system to cover a wider range of activities.
Authors: Diego Alfonso López-Mora; Marina Sizova; Montserrat Estorch; Albert Flotats; Valle Camacho; Alejandro Fernández; Safae Abouzian; Francisco Fuentes-Ocampo; José Ignacio Pérez Garcia; Ana Isabel Chico Ballesteros; Joan Duch; Anna Domènech; Antonio Moral Duarte; Ignasi Carrió Journal: Eur J Nucl Med Mol Imaging Date: 2020-01-09 Impact factor: 9.236
Authors: Varsha Viswanath; Austin R Pantel; Margaret E Daube-Witherspoon; Robert Doot; Mark Muzi; David A Mankoff; Joel S Karp Journal: IEEE Trans Radiat Plasma Med Sci Date: 2020-09-02
Authors: Benjamin A Spencer; Eric Berg; Jeffrey P Schmall; Negar Omidvari; Edwin K Leung; Yasser G Abdelhafez; Songsong Tang; Zilin Deng; Yun Dong; Yang Lv; Jun Bao; Weiping Liu; Hongdi Li; Terry Jones; Ramsey D Badawi; Simon R Cherry Journal: J Nucl Med Date: 2020-10-02 Impact factor: 10.057