Literature DB >> 3030266

6-beta-Iodopenicillanate as a probe for the classification of beta-lactamases.

F De Meester, J M Frère, S G Waley, S J Cartwright, R Virden, F Lindberg.   

Abstract

An inactivator of serine beta-lactamases, 6 beta-iodopenicillanate, can be utilized as a probe in the classification of beta-lactamases. It is a substrate for class-B Zn2+-containing beta-lactamase II. Although it inactivates enzymes from both classes A and C, it is much more efficient for the former group, with which it sometimes interacts following a branched pathway. On the basis of these observations, predictions are made concerning the class to which several enzymes belong.

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Year:  1986        PMID： 3030266      PMCID： PMC1147325          DOI： 10.1042/bj2390575

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  29 in total

1.  The reversible deactivation of beta-lactamase from Staphylococcus aureus by quinacillin and cephaloridine and its modification by antibodies.

Authors:  E A Carrey; R Virden; R H Pain
Journal:  Biochim Biophys Acta       Date:  1984-03-29

2.  6-beta-bromo- and 6-beta-iodo penicillanic acid, two novel beta-lactamase inhibitors.

Authors:  R Wise; J M Andrews; N Patel
Journal:  J Antimicrob Chemother       Date:  1981-05       Impact factor: 5.790

3.  ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase type.

Authors:  B Jaurin; T Grundström
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

4.  Interaction of clavulanate with the beta-lactamases of Streptomyces albus G and Actinomadura R39.

Authors:  J M Frère; C Dormans; V M Lenzini; C Duyckaerts
Journal:  Biochem J       Date:  1982-12-01       Impact factor: 3.857

5.  Interaction of beta-iodopenicillanate with the beta-lactamases of Streptomyces albus G and Actinomadura R39.

Authors:  J M Frère; C Dormans; C Duyckaerts; J De Graeve
Journal:  Biochem J       Date:  1982-12-01       Impact factor: 3.857

6.  Purification and properties of the exocellular beta-lactamase of Actinomadura strain R39.

Authors:  C Duez; J M Frère; J M Ghuysen; J Van Beeumen; L Delcambe; L Dierickx
Journal:  Biochim Biophys Acta       Date:  1982-01-04

7.  The exocellular beta-lactamase of Streptomyces albus G. Purification, properties and comparison with the exocellular DD-carboxypeptidase.

Authors:  C Duez; J M Frère; D Klein; M Noël; J M Ghuysen; L Delcambe; L Dierickx
Journal:  Biochem J       Date:  1981-01-01       Impact factor: 3.857

8.  Purification of beta-lactamases by affinity chromatography on phenylboronic acid-agarose.

Authors:  S J Cartwright; S G Waley
Journal:  Biochem J       Date:  1984-07-15       Impact factor: 3.857

9.  Kinetics of inactivation of beta-lactamase I by 6 beta-bromopenicillanic acid.

Authors:  V Knott-Hunziker; B S Orlek; P G Sammes; S G Waley
Journal:  Biochem J       Date:  1980-06-01       Impact factor: 3.857

10.  Comparison of the overlapping frd and ampC operons of Escherichia coli with the corresponding DNA sequences in other gram-negative bacteria.

Authors:  S Bergström; F P Lindberg; O Olsson; S Normark
Journal:  J Bacteriol       Date:  1983-09       Impact factor: 3.490
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  27 in total

1.  Biochemical characterization of laboratory mutants of extended-spectrum beta-lactamase TEM-60.

Authors:  Bibiana Caporale; Nicola Franceschini; Mariagrazia Perilli; Bernardetta Segatore; Gian Maria Rossolini; Gianfranco Amicosante
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

Review 2.  Characterization of beta-lactamases.

Authors:  K Bush
Journal:  Antimicrob Agents Chemother       Date:  1989-03       Impact factor: 5.191

3.  The active sites of the beta-lactamases of Streptomyces cacaoi and Streptomyces albus G.

Authors:  F De Meester; B Joris; M V Lenzini; P Dehottay; T Erpicium; J Dusart; D Klein; J M Ghuysen; J M Frère; J Van Beeumen
Journal:  Biochem J       Date:  1987-06-01       Impact factor: 3.857

4.  Inactivation of the thiol RTEM-1 beta-lactamase by 6-beta-bromopenicillanic acid. Identity of the primary active-site nucleophile.

Authors:  A K Knap; R F Pratt
Journal:  Biochem J       Date:  1987-10-01       Impact factor: 3.857

5.  The diversity of the catalytic properties of class A beta-lactamases.

Authors:  A Matagne; A M Misselyn-Bauduin; B Joris; T Erpicum; B Granier; J M Frère
Journal:  Biochem J       Date:  1990-01-01       Impact factor: 3.857

6.  Ragged N-termini and other variants of class A beta-lactamases analysed by chromatofocusing.

Authors:  A Matagne; B Joris; J Van Beeumen; J M Frère
Journal:  Biochem J       Date:  1991-02-01       Impact factor: 3.857

7.  Ceftazidime and aztreonam resistance in Providencia stuartii: characterization of a natural TEM-derived extended-spectrum beta-lactamase, TEM-60.

Authors:  N Franceschini; M Perilli; B Segatore; D Setacci; G Amicosante; A Mazzariol; G Cornaglia
Journal:  Antimicrob Agents Chemother       Date:  1998-06       Impact factor: 5.191

8.  Beta-lactamases as fully efficient enzymes. Determination of all the rate constants in the acyl-enzyme mechanism.

Authors:  H Christensen; M T Martin; S G Waley
Journal:  Biochem J       Date:  1990-03-15       Impact factor: 3.857

9.  A survey of the kinetic parameters of class C beta-lactamases. Cephalosporins and other beta-lactam compounds.

Authors:  M Galleni; G Amicosante; J M Frère
Journal:  Biochem J       Date:  1988-10-01       Impact factor: 3.857

10.  A survey of the kinetic parameters of class C beta-lactamases. Penicillins.

Authors:  M Galleni; J M Frère
Journal:  Biochem J       Date:  1988-10-01       Impact factor: 3.857
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