Literature DB >> 9624494

Ceftazidime and aztreonam resistance in Providencia stuartii: characterization of a natural TEM-derived extended-spectrum beta-lactamase, TEM-60.

N Franceschini1, M Perilli, B Segatore, D Setacci, G Amicosante, A Mazzariol, G Cornaglia.   

Abstract

A plasmid-encoded beta-lactamase produced from a clinical strain of Providencia stuartii has been purified and characterized. The gene coding for the beta-lactamase was cloned and sequenced. It appears to be a new natural TEM-derived enzyme, named TEM-60. Point mutations (Q39K, L51P, E104K, and R164S) are present with respect to the TEM-1 enzyme; the mutation L51P has never been previously reported, with the exception of the chromosomally encoded extended-spectrum beta-lactamase PER-1. Kinetic parameters relative to penicillins, cephalosporins, and monobactams other than mechanism-based inactivators were related to the in vitro susceptibility phenotype.

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Year:  1998        PMID： 9624494      PMCID： PMC105622     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

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Journal:  Antimicrob Agents Chemother       Date:  1989-03       Impact factor: 5.191

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Journal:  J Antimicrob Chemother       Date:  1997-08       Impact factor: 5.790

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Journal:  Biochem Pharmacol       Date:  1987-07-15       Impact factor: 5.858

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Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

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Authors:  R P Ambler
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1980-05-16       Impact factor: 6.237

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Journal:  Nature       Date:  1976 Dec 23-30       Impact factor: 49.962

10.  Rapid procedure for detection and isolation of large and small plasmids.

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Journal:  J Bacteriol       Date:  1981-03       Impact factor: 3.490
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  11 in total

1.  New TEM variant (TEM-92) produced by Proteus mirabilis and Providencia stuartii isolates.

Authors:  C de Champs; C Monne; R Bonnet; W Sougakoff; D Sirot; C Chanal; J Sirot
Journal:  Antimicrob Agents Chemother       Date:  2001-04       Impact factor: 5.191

2.  TEM-24 produced by four different species of Enterobacteriaceae, including Providencia rettgeri, in a single patient.

Authors:  H Marchandin; C Carriere; D Sirot; H J Pierre; H Darbas
Journal:  Antimicrob Agents Chemother       Date:  1999-08       Impact factor: 5.191

3.  Occurrence of extended-spectrum beta-lactamases in members of the family Enterobacteriaceae in Italy: implications for resistance to beta-lactams and other antimicrobial drugs.

Authors:  T Spanu; F Luzzaro; M Perilli; G Amicosante; A Toniolo; G Fadda
Journal:  Antimicrob Agents Chemother       Date:  2002-01       Impact factor: 5.191

4.  Molecular characterization of extended-spectrum beta-lactamases produced by nosocomial isolates of Enterobacteriaceae from an Italian nationwide survey.

Authors:  Mariagrazia Perilli; Emanuela Dell'Amico; Bernardetta Segatore; Maria Rosaria de Massis; Ciro Bianchi; Francesco Luzzaro; Gian Maria Rossolini; Antonio Toniolo; Giuseppe Nicoletti; Gianfranco Amicosante
Journal:  J Clin Microbiol       Date:  2002-02       Impact factor: 5.948

5.  Identification of TEM-10 beta-lactamase in a Kluyvera sp. and other Enterobacteriaceae at a Portuguese hospital.

Authors:  A Duarte; N Faria; T Conceição; M Correia; L M Lito; J Melo Cristino; M J Salgado; R Tenreiro
Journal:  Antimicrob Agents Chemother       Date:  2002-12       Impact factor: 5.191

6.  Predicting evolution by in vitro evolution requires determining evolutionary pathways.

Authors:  Barry G Hall
Journal:  Antimicrob Agents Chemother       Date:  2002-09       Impact factor: 5.191

7.  Biochemical characterization of laboratory mutants of extended-spectrum beta-lactamase TEM-60.

Authors:  Bibiana Caporale; Nicola Franceschini; Mariagrazia Perilli; Bernardetta Segatore; Gian Maria Rossolini; Gianfranco Amicosante
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

8.  Novel genetic structure associated with an extended-spectrum beta-lactamase blaVEB gene in a Providencia stuartii clinical isolate from Algeria.

Authors:  Daniel Aubert; Thierry Naas; Marie-Frédérique Lartigue; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2005-08       Impact factor: 5.191

9.  Nosocomial dissemination of extended-spectrum β-lactamase VEB-1a-producing Providencia stuartii isolates in a Tunisian hospital.

Authors:  H Lahlaoui; L Poirel; M B Moussa; M Ferjani; B Omrane; P Nordmann
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-03-27       Impact factor: 3.267

10.  Implication of porins in beta-lactam resistance of Providencia stuartii.

Authors:  Que-Tien Tran; Kozhinjampara R Mahendran; Eric Hajjar; Matteo Ceccarelli; Anne Davin-Regli; Mathias Winterhalter; Helge Weingart; Jean-Marie Pagès
Journal:  J Biol Chem       Date:  2010-07-28       Impact factor: 5.157
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