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Literature DB >> 3023884

Structure of the c-Ki-ras gene in a rat fibrosarcoma induced by 1,8-dinitropyrene.

T Tahira, K Hayashi, M Ochiai, N Tsuchida, M Nagao, T Sugimura.

Abstract

Restriction enzyme maps were made of the region around exons 1 and 2 of activated c-Ki-ras of a fibrosarcoma (1,8-DNP2) induced in a rat by 1,8-dinitropyrene. Nucleotide sequence analysis revealed that activated c-Ki-ras shows a G----T transversion in codon 12 and consequently encodes cysteine instead of glycine in normal rat c-Ki-ras.

Entities: Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 1986 PMID： 3023884 PMCID： PMC367651 DOI： 10.1128/mcb.6.4.1349-1351.1986

Source DB: PubMed Journal: Mol Cell Biol ISSN： 0270-7306 Impact factor: 4.272

11 in total

1. The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes.

Authors: R W Ellis; D Defeo; T Y Shih; M A Gonda; H A Young; N Tsuchida; D R Lowy; E M Scolnick
Journal: Nature Date: 1981-08-06 Impact factor: 49.962

2. Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene.

Authors: J P McGrath; D J Capon; D H Smith; E Y Chen; P H Seeburg; D V Goeddel; A D Levinson
Journal: Nature Date: 1983 Aug 11-17 Impact factor: 49.962

Review 3. The molecular genetics of cellular oncogenes.

Authors: H E Varmus
Journal: Annu Rev Genet Date: 1984 Impact factor: 16.830

4. Induction of sarcomas in rats by subcutaneous injection of dinitropyrenes.

Authors: H Ohgaki; C Negishi; K Wakabayashi; K Kusama; S Sato; T Sugimura
Journal: Carcinogenesis Date: 1984-05 Impact factor: 4.944

5. Nucleotide sequence of the oncogene encoding the p21 transforming protein of Kirsten murine sarcoma virus.

Authors: N Tsuchida; T Ryder; E Ohtsubo
Journal: Science Date: 1982-09-03 Impact factor: 47.728

6. DNA sequencing with chain-terminating inhibitors.

Authors: F Sanger; S Nicklen; A R Coulson
Journal: Proc Natl Acad Sci U S A Date: 1977-12 Impact factor: 11.205

7. Three different mutations in codon 61 of the human N-ras gene detected by synthetic oligonucleotide hybridization.

Authors: J L Bos; M Verlaan-de Vries; A M Jansen; G H Veeneman; J H van Boom; A J van der Eb
Journal: Nucleic Acids Res Date: 1984-12-11 Impact factor: 16.971

8. Activation of a c-K-ras oncogene by somatic mutation in mouse lymphomas induced by gamma radiation.

Authors: I Guerrero; A Villasante; V Corces; A Pellicer
Journal: Science Date: 1984-09-14 Impact factor: 47.728

9. Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1.

Authors: K Shimizu; D Birnbaum; M A Ruley; O Fasano; Y Suard; L Edlund; E Taparowsky; M Goldfarb; M Wigler
Journal: Nature Date: 1983 Aug 11-17 Impact factor: 49.962

10. Activation of K-ras and oncogenes other than ras family in rat fibrosarcomas induced by 1,8-dinitropyrene.

Authors: M Ochiai; M Nagao; T Tahira; F Ishikawa; K Hayashi; H Ohgaki; M Terada; N Tsuchida; T Sugimura
Journal: Cancer Lett Date: 1985-11 Impact factor: 8.679

13 in total

1. Identification of an activated c-Ki-ras oncogene in rat liver tumors induced by aflatoxin B1.

Authors: G McMahon; L Hanson; J J Lee; G N Wogan
Journal: Proc Natl Acad Sci U S A Date: 1986-12 Impact factor: 11.205

2. Characterization of c-Ki-ras and N-ras oncogenes in aflatoxin B1-induced rat liver tumors.

Authors: G McMahon; E F Davis; L J Huber; Y Kim; G N Wogan
Journal: Proc Natl Acad Sci U S A Date: 1990-02 Impact factor: 11.205

3. Fast repair of O6-ethylguanine, but not O6-methylguanine, in transcribed genes prevents mutation of H-ras in rat mammary tumorigenesis induced by ethylnitrosourea in place of methylnitrosourea.

Authors: J Engelbergs; J Thomale; A Galhoff; M F Rajewsky
Journal: Proc Natl Acad Sci U S A Date: 1998-02-17 Impact factor: 11.205

Review 4. Human cancer and cellular oncogenes.

Authors: S Nishimura; T Sekiya
Journal: Biochem J Date: 1987-04-15 Impact factor: 3.857